Recent Publications

2024 (articles in alphabetic order)

1. Bessa-Andres, C., Pinto-Cardoso, R., Tarasova, K., Pereira-Goncalves, A. L., Gaio-Ferreira-Castro, J. M., Carvalho, L. S., Costa, M. A., Ferreirinha, F., Canadas-Sousa, A., Marinhas, J., Freitas, R., Lemos, R., Vilaca, A., Oliveira, A., Correia-de-Sa, P. and Noronha-Matos, J. B. (2024). Mechanical stimulation-induced purinome priming fosters osteogenic differentiation and osteointegration of mesenchymal stem cells from the bone marrow of post-menopausal women. Stem Cell Res Ther, 15 (1): 168. https://doi.org/10.1186/s13287-024-03775-4

2. Bessa-Goncalves, M., Braganca, B., Martins-Dias, E., Vinhas, A., Certal, M., Rodrigues, T., Ferreirinha, F., Costa, M. A., Correia-de-Sa, P. and Fontes-Sousa, A. P. (2024). Blockage of the adenosine A(2B) receptor prevents cardiac fibroblasts overgrowth in rats with pulmonary arterial hypertension. Purinergic Signal, in press https://doi.org/10.1007/s11302-023-09952-z

3. Cardoso, D., Bezerra, S., Soares-Dos-Reis, R., Sa, M. J. and Guimaraes, J. (2024). Optic neuropathy diagnosis in the emergency room - retrospective observational study of the last 18 years. Eur J Ophthalmol, 34 (1): 267-280. https://doi.org/10.1177/11206721231173005

4. Esteves-Guimaraes, J., Matos, J. I., Leal-Sousa, B., Oliveira, P., Lobo, L., Silvestre-Ferreira, A. C., Soares, C. S., Rodriguez-Escolar, I., Carreton, E., Morchon, R., Fontes-Sousa, A. P. and Montoya-Alonso, J. A. (2024). Current State of Canine Heartworm in Portugal. Animals (Basel), 14 (9): https://doi.org/10.3390/ani14091300

5. Godinho, N., Morato, M., Albino-Teixeira, A., Caldas Afonso, A., Sousa, T. and Correia-Costa, L. (2024). Gender-related differences in cardiometabolic risk factors and oxidative stress among prepubertal children with obesity. J Pediatr Endocrinol Metab, 37 (1): 42-51. https://doi.org/10.1515/jpem-2023-0286

6. Goncalves, J. M., Goncalves, J. N. D., Sousa, L. F., Rodrigues, L. R., Correia-de-Sa, P., Coutinho, P. J. G., Castanheira, E. M. S., Oliveira, R. and Dias, A. M. (2024). 2,4,5-Triaminopyrimidines as blue fluorescent probes for cell viability monitoring: synthesis, photophysical properties, and microscopy applications. Org Biomol Chem, in press https://doi.org/10.1039/d4ob00092g

7. Lopes, C., Sousa, C., Fraga, A., Guimaraes, J., Vicente, S. and Sa, M. J. (2024). Cognitive impairment in Neuromyelitis Optica Spectrum Disorder: A retrospective study using the Brief International cognitive Assessment for Multiple Sclerosis (BICAMS). Appl Neuropsychol Adult, in press 1-7. https://doi.org/10.1080/23279095.2023.2210242

8. Mendes, G., Madanelo, M., Vila, F., Versos, R., Teixeira, B. L., Rocha, M. A., Mesquita, S., Marques-Monteiro, M., Principe, P., Ramires, R., Lindoro, J., Fraga, A. and Silva-Ramos, M. (2024). Transperitoneal vs. Retroperitoneal Approach in Laparoscopic Partial Nephrectomy for Posterior Renal Tumors: A Retrospective, Multi-Center, Comparative Study. J Clin Med, 13 (3): https://doi.org/10.3390/jcm13030701

9. Mesquita, S., Marques-Monteiro, M., Madanelo, M., Rocha, M. A., Vinagre, N., Fraga, A., Cavadas, V., Machado, R. and Silva-Ramos, M. (2024). Nephrectomy with Autotransplantation-A Key Treasure. J Clin Med, 13 (6): https://doi.org/10.3390/jcm13061641

10. Oliveira, A., Azevedo, M., Seixas, R., Martinho, R., Serrao, P. and Moreira-Rodrigues, M. (2024). Glucose may Contribute to Retrieval and Reconsolidation of Contextual Fear Memory Through Hippocampal Nr4a3 and Bdnf mRNA Expression and May Act Synergically with Adrenaline. Mol Neurobiol, in press https://doi.org/10.1007/s12035-023-03745-6

11. Pedro, B., Mavropoulou, A., Oyama, M. A., Linney, C., Neves, J., Dukes-McEwan, J., Fontes-Sousa, A. P. and Gelzer, A. R. (2024). Longitudinal analysis of echocardiographic and cardiac biomarker variables in dogs with atrial fibrillation: The optimal rate control in dogs with atrial fibrillation II study. J Vet Intern Med, in press https://doi.org/10.1111/jvim.17120

12. Pinto, M., Silva, T. B., Sardao, V. A., Simoes, R., Albuquerque, B., Oliveira, P. J., Valente, M. J., Remiao, F., Soares-da-Silva, P., Fernandes, C. and Borges, F. (2024). Cellular and Mitochondrial Toxicity of Tolcapone, Entacapone, and New Nitrocatechol Derivatives. ACS Pharmacol Transl Sci, 7 (5): 1637-1649. https://doi.org/10.1021/acsptsci.4c00124

13. Rebouta, J., Doria, L., Coelho, A., Fonseca, M. M., Castilla-Fernandez, G., Pires, N. M., Vieira-Coelho, M. A. and Loureiro, A. I. (2024). HR/MS-based lipidome analysis of rat brain modulated by tolcapone. J Pharm Biomed Anal, 241 115971. https://doi.org/10.1016/j.jpba.2024.115971

14. Teixeira, A., Teixeira, M., Gaio, R., Torres, T., Magina, S., Dinis, M. A. P., Sousa-Lobo, J., Almeida, I., Peixoto, M. and Almeida, V. (2024). Influence of Clinical and Psychosocial Factors on the Adherence to Topical Treatment in Psoriasis. Healthcare (Basel), 12 (8): https://doi.org/10.3390/healthcare12080822

15. Torres, T., Antunes, J., Brasileiro, A., Alves, J., Bernardo, D., Ramos, J., Sousa, D., Castro, C., Gusmao Palmeiro, A., Aparicio Martins, A., Fazendeiro Matos, J., Vieira Granja, B., Ponte, P., Marques Pinto, G., Quirino, P., Menezes Brandao, F., Teixeira, L., Magina, S., Paiva Lopes, M. J., Oliveira, H., Varela, P., Telles Sousa, J., Filipe, P. and Tavares Bello, R. (2024). Clinical course and disease burden of patients with generalized pustular psoriasis in Portugal: a multicenter retrospective cohort study. J Dermatolog Treat, 35 (1): 2345728. https://doi.org/10.1080/09546634.2024.2345728

16. Torres, T., Varela, P., Mendes Bastos, P., Magina, S., Henrique, M. and Ferreira, P. (2024). Tildrakizumab for the treatment of moderate-to-severe psoriasis: a 52-week, real-world Portuguese multicentric study. Drugs Context, 13 https://doi.org/10.7573/dic.2023-12-5

17. Tymko, M. M., Drapeau, A., Vieira-Coelho, M. A., Labrecque, L., Imhoff, S., Coombs, G. B., Langevin, S., Fortin, M., Chateauvert, N., Ainslie, P. N. and Brassard, P. (2024). Acute isometric and dynamic exercise do not alter cerebral sympathetic nerve activity in healthy humans. J Cereb Blood Flow Metab, in press 271678X241248228. https://doi.org/10.1177/0271678X241248228

18. Vieira Granja, B., Amoedo, P., Gomes, N. P., Costa, C., Azevedo, F. and Magina, S. (2024). Pityriasis rubra pilaris after COVID-19 vaccination: successful treatment with Ustekinumab. An Bras Dermatol, in press https://doi.org/10.1016/j.abd.2023.07.009

2023 (articles in alphabetic order)

1. (2023). Corrigendum for Cosme et al., volume 323, 2022, p. G410-G419. Am J Physiol Gastrointest Liver Physiol, 324 (1): G89. https://doi.org/10.1152/ajpgi.00139.2023_COR

2. Amoedo, P., Cerejeira, A., Moreira, F., Coelho, A., Barros, A. M., Moreira, E., Magina, S., Silva-Ramos, M. and Azevedo, F. (2023). Metastatic hidradenocarcinoma: a report of two rare cases. Eur J Dermatol, 33 (3): 241-244. https://doi.org/10.1684/ejd.2023.4478

3. Azevedo, M., Martinho, R., Oliveira, A., Correia-de-Sa, P. and Moreira-Rodrigues, M. (2023). Molecular pathways underlying sympathetic autonomic overshooting leading to fear and traumatic memories: looking for alternative therapeutic options for post-traumatic stress disorder. Front Mol Neurosci, 16 1332348. https://doi.org/10.3389/fnmol.2023.1332348

4. Barrocas, P., Vieira, A. C. F., Almeida, H., Teixeira, J., Gomes, M. J., Chevalier, E., Soares-da-Silva, P. and Vasconcelos, T. (2023). Over-blending effect of lubricants on capsules manufacturing: a simple and fast wettability technique to predict batch dissolution performance. Pharm Dev Technol, 28 (3-4): 363-370. https://doi.org/10.1080/10837450.2023.2196332

5. Bessa, C., Loureiro, J. B., Barros, M., Isca, V. M. S., Sardao, V. A., Oliveira, P. J., Bernardino, R. L., Herman-de-Sousa, C., Costa, M. A., Correia-de-Sa, P., Alves, M. G., Rijo, P. and Saraiva, L. (2023). Counteracting Colon Cancer by Inhibiting Mitochondrial Respiration and Glycolysis with a Selective PKCdelta Activator. Int J Mol Sci, 24 (6): 5710. https://doi.org/10.3390/ijms24065710

6. Correia, G. and Magina, S. (2023). Efficacy of topical vitamin C in melasma and photoaging: A systematic review. J Cosmet Dermatol, 22 (7): 1938-1945. https://doi.org/10.1111/jocd.15748

7. Cosme, D., Soares-da-Silva, P. and Magro, F. (2023). Long-term effect of Toll-like receptor-2, -4, -5, -7 and NOD2 stimulation on Na(+),K(+)-ATPase activity and expression in intestinal epithelial cells. Am J Physiol Cell Physiol, 324 (5): C1028-C1038. https://doi.org/10.1152/ajpcell.00208.2022

8. de Sousa, H. T., Gullo, I. and Magro, F. (2023). Fibromuscular Expansion in Crohn's Disease Ileal Strictures: An Open Issue. Clin Gastroenterol Hepatol, 21 (5): 1378-1380. https://doi.org/10.1016/j.cgh.2022.06.023

9. Fernandes, A. A., Grangeia, A., Dias, L. and Guimaraes, J. (2023). Expanding the genetic spectrum of ALKU syndrome: Compound heterozygosity for two deleterious variants in SMG8 gene. Am J Med Genet A, 191 (8): 2204-2208. https://doi.org/10.1002/ajmg.a.63242

10. Ferreira-Duarte, M., Oliveira, L. C. G., Quintas, C., Esteves-Monteiro, M., Duarte-Araujo, M., Sousa, T., Casarini, D. E. and Morato, M. (2023). ACE and ACE2 catalytic activity in the fecal content along the gut. Neurogastroenterol Motil, 35 (9): e14598. https://doi.org/10.1111/nmo.14598

11. Gaspar, A. R., Andrade, B., Mosca, S., Ferreira-Duarte, M., Teixeira, A., Cosme, D., Albino-Teixeira, A., Ronchi, F. A., Leite, A. P., Casarini, D. E., Areias, J. C., Sousa, T., Afonso, A. C., Morato, M. and Correia-Costa, L. (2023). Association between blood pressure and angiotensin-converting enzymes activity in prepubertal children *. J Hypertens, 41 (4): 545-553. https://doi.org/10.1097/HJH.0000000000003345

12. Giralt, L., Perez-Fernandez, S., Adan, A., Figueira, L., Fonollosa, A. and Group*, I. S. (2023). Clinical Features and Outcomes of Tubulointerstitial Nephritis and Uveitis Syndrome in Spain and Portugal: The IBERTINU Project. Ocul Immunol Inflamm, 31 (2): 286-291. https://doi.org/10.1080/09273948.2022.2026413

13. Gouveia, R., Cruz, V. T., Antao, J. and Almeida, L. (2023). Interpersonal Values of Patients Participating in Phase II-III Clinical Trials: Implications for Clinical Trial Representativeness. Pharmaceut Med, 37 (4): 319-329. https://doi.org/10.1007/s40290-023-00479-7

14. Henriques, S. C., Paixao, P., Almeida, L. and Silva, N. E. (2023). Predictive Potential of C(max) Bioequivalence in Pilot Bioavailability/Bioequivalence Studies, through the Alternative f(2) Similarity Factor Method. Pharmaceutics, 15 (10): https://doi.org/10.3390/pharmaceutics15102498

15. Koepp, M. J., Trinka, E., Mah, Y. H., Bentes, C., Knake, S., Gigli, G. L., Serratosa, J. M., Zelano, J., Magalhaes, L. M., Pereira, A., Moreira, J. and Soares-da-Silva, P. (2023). Antiepileptogenesis after stroke-trials and tribulations: Methodological challenges and recruitment results of a Phase II study with eslicarbazepine acetate. Epilepsia Open, 8 (3): 1190-1201. https://doi.org/10.1002/epi4.12735

16. Mathias, L. S., Herman-de-Sousa, C., Cury, S. S., Nogueira, C. R., Correia-de-Sa, P. and de Oliveira, M. (2023). RNA-seq reveals that anti-obesity irisin and triiodothyronine (T3) hormones differentially affect the purinergic signaling transcriptomics in differentiated human adipocytes. Biochim Biophys Acta Mol Cell Biol Lipids, 1868 (4): 159276. https://doi.org/10.1016/j.bbalip.2022.159276

17. Miranda-Lourenco, C., Rosa, J., Rei, N., Belo, R. F., Lopes, A. L., Silva, D., Vieira, C., Magalhaes-Cardoso, T., Viais, R., Correia-de-Sa, P., Sebastiao, A. M. and Diogenes, M. J. (2023). Adenosinergic System and BDNF Signaling Changes as a Cross-Sectional Feature of RTT: Characterization of Mecp2 Heterozygous Mouse Females. Int J Mol Sci, 24 (22): 16249. https://doi.org/10.3390/ijms242216249

18. Noronha-Matos, J. B., Pinto-Cardoso, R., Bessa-Andres, C., Magalhaes-Cardoso, M. T., Ferreirinha, F., Costa, M. A., Marinhas, J., Freitas, R., Lemos, R., Vilaca, A., Oliveira, A., Pelletier, J., Sevigny, J. and Correia-de-Sa, P. (2023). Silencing NTPDase3 activity rehabilitates the osteogenic commitment of post-menopausal stem cell bone progenitors. Stem Cell Res Ther, 14 (1): 97. https://doi.org/10.1186/s13287-023-03315-6

19. Oliveira, A., Seixas, R., Pereira, F., Azevedo, M., Martinho, R., Serrao, P. and Moreira-Rodrigues, M. (2023). Insulin enhances contextual fear memory independently of its effect in increasing plasma adrenaline. Life Sci, 328 121881. https://doi.org/10.1016/j.lfs.2023.121881

20. Oliveira, K. B. V., Severo, J. S., Silva, A., Santos, B., Mendes, P. H. M., Sabino, J. P. J., Filho, A., Correia-de-Sa, P., Santos, A. A. D. and Silva, M. (2023). P2X7 receptor antagonist improves gastrointestinal disorders in spontaneously hypertensive rats. Braz J Med Biol Res, 56 e12569. https://doi.org/10.1590/1414-431X2023e12569

21. Pedro, B., Mavropoulou, A., Oyama, M. A., Linney, C., Neves, J., Dukes-McEwan, J., Fontes-Sousa, A. P. and Gelzer, A. R. (2023). Optimal rate control in dogs with atrial fibrillation-ORCA study-Multicenter prospective observational study: Prognostic impact and predictors of rate control. J Vet Intern Med, 37 (3): 887-899. https://doi.org/10.1111/jvim.16666

22. Pereira-Silva, R., Serrao, P., Lourenca Neto, F. and Martins, I. (2023). Diffuse noxious inhibitory controls in chronic joint inflammatory Pain: Study of the descending serotonergic modulation mediated through 5HT3 receptors. Neurobiol Pain, 13 100123. https://doi.org/10.1016/j.ynpai.2023.100123

23. Pinto-Cardoso, R., Bessa-Andres, C., Correia-de-Sa, P. and Bernardo Noronha-Matos, J. (2023). Could hypoxia rehabilitate the osteochondral diseased interface? Lessons from the interplay of hypoxia and purinergic signals elsewhere. Biochem Pharmacol, 214 115646. https://doi.org/10.1016/j.bcp.2023.115646

24. Portela Moreira, I., Henriques, T., Vieira-Coelho, M. A. and Guimaraes, J. (2023). Dysfunction of norepinephrine and its metabolites in Alzheimer's dementia - A review with meta-analysis. Ageing Res Rev, 83 101784. https://doi.org/10.1016/j.arr.2022.101784

25. Reina-Couto, M., Roboredo-Madeira, M., Pereira-Terra, P., Silva-Pereira, C., Martins, S., Teixeira-Santos, L., Pinho, D., Dias, A., Cordeiro, G., Dias, C. C., Sarmento, A., Tavares, M., Guimaraes, J. T., Roncon-Albuquerque, R., Paiva, J. A., Albino-Teixeira, A. and Sousa, T. (2023). Evaluation of urinary cysteinyl leukotrienes as biomarkers of severity and putative therapeutic targets in COVID-19 patients. Inflamm Res, 72 (3): 475-491. https://doi.org/10.1007/s00011-022-01682-z

26. Rocha, M. A., Mendes, G., Castro, L. F., Mesquita, S., Teixeira, B. L., Madanelo, M., Vital, J. A., Marques-Monteiro, M., Vinagre, N., Oliveira, B., Magalhaes, M., Principe, P., Ferreira, H. and Silva-Ramos, M. (2023). Outcomes of Urinary Tract Endometriosis-Laparoscopic Treatment: A 10-Year Retrospective Study. J Clin Med, 12 (22): https://doi.org/10.3390/jcm12226996

27. Santos, W. L. L., da Silva Pinheiro, C., de Oliveira Santos, R., da Silva, A. C. A., Severo, J. S., Mendes, P. H. M., de Sousa, L. C., de Sousa, O. M. C., Dos Santos, B. L. B., de Oliveira, K. B. V., Freitas, A. K., Torres-Leal, F. L., Dos Santos, A. A. and da Silva, M. T. B. (2023). Physical exercise alleviates oxidative stress in brown adipose tissue and causes changes in body composition and nutritional behavior in rats with polycystic ovary syndrome. Life Sci, 325 121754. https://doi.org/10.1016/j.lfs.2023.121754

28. Severo, J. S., Barros, V. J. D., Mendes, P. H. M., dos Santos, B. L. B., da Silva, A. C. A., de Oliveira, K. B. V., de Moura, M. S. B., Viola, P. C. D. F., Nogueira, N. D., Parente, J. M. L., Lima, M. M., dos Santos, A. A. and Silva, M. T. B. (2023). Phase angle values and ultra-processed food consumption are associated with changes in oxidative stress in inflammatory bowel disease patients. Clinical Nutrition Espen, 57 10-20. https://doi.org/10.1016/j.clnesp.2023.06.006

29. Sousa, T., Pinho, D., Recchiuti, A., Isopi, E. and Verri, W. A., Jr. (2023). Editorial: Specialized proresolving mediators: Benefits within and beyond inflammation resolution in cardiometabolic, neurological and psychiatric disorders. Front Physiol, 14 1176700. https://doi.org/10.3389/fphys.2023.1176700

30. Sousa-Soares, C., Noronha-Matos, J. B. and Correia-de-Sa, P. (2023). Purinergic Tuning of the Tripartite Neuromuscular Synapse. Mol Neurobiol, 60 (7): 4084-4104. https://doi.org/10.1007/s12035-023-03317-8

31. Teixeira-Santos, L., Martins, S., Sousa, T., Albino-Teixeira, A. and Pinho, D. (2023). The pro-resolving lipid mediator Maresin 1 ameliorates pain responses and neuroinflammation in the spared nerve injury-induced neuropathic pain: A study in male and female mice. PLoS One, 18 (6): e0287392. https://doi.org/10.1371/journal.pone.0287392

32. Teixeira-Santos, L., Verissimo, E., Martins, S., Sousa, T., Albino-Teixeira, A. and Pinho, D. (2023). Effects of NADPH Oxidase Isoform-2 (NOX2) Inhibition on Behavioral Responses and Neuroinflammation in a Mouse Model of Neuropathic Pain. Biomedicines, 11 (2): 416. https://doi.org/10.3390/biomedicines11020416

33. Triguinho, A., Fontes-Sousa, A. P., Pimenta, J. and Cotovio, M. (2023). Electrocardiographic Reference Values in Clinically Healthy Lusitano Horses. Vet Sci, 10 (8): https://doi.org/10.3390/vetsci10080518

34. Vieira-Coelho, M. A. and Martel, F. (2023). Inhibition of kidney potassium channels by fluoxetine: In vivo and in vitro studies. Fundam Clin Pharmacol, 37 (2): 226-234. https://doi.org/10.1111/fcp.12833

35. Wiszpolska, M., Lepiarczyk, E., Mazdziarz, M. A., Paukszto, L., Makowczenko, K. G., Lipka, A., Lopienska-Biernat, E., Makowska, K., Gonkowski, S., Correia-de-Sa, P. and Majewska, M. (2023). The Carcinogenic Potential of Bisphenol A in the Liver Based on Transcriptomic Studies. Cancers (Basel), 15 (20): https://doi.org/10.3390/cancers15205014

36. Wiszpolska, M., Lepiarczyk, E., Paukszto, L., Makowczenko, K. G., Lipka, A., Mazdziarz, M. A., Polak, I., Makowska, K., Gonkowski, S., Correia-de-Sa, P. and Majewska, M. (2023). A comprehensive transcriptomic analysis of the bisphenol A affected kidney in mice. Front Mol Biosci, 10 1260716. https://doi.org/10.3389/fmolb.2023.1260716

2022 (articles in alphabetic order)

Amoedo, P., Matos, P. and Magina, S. (2022). sQuiz your knowledge! Symmetrical palpebral plaques following blepharoplasty. Eur J Dermatol, 32 (6): 820-822. https://doi.org/10.1684/ejd.2022.4389
Andrikakou, P., Reebye, V., Vasconcelos, D., Yoon, S., Voutila, J., George, A. J. T., Swiderski, P., Habib, R., Catley, M., Blakey, D., Habib, N. A., Rossi, J. J. and Huang, K. W. (2022). Enhancing SIRT1 Gene Expression Using Small Activating RNAs: A Novel Approach for Reversing Metabolic Syndrome. Nucleic Acid Ther, 32 (6): 486-496. https://doi.org/10.1089/nat.2021.0115
Antonio, T., Soares-da-Silva, P., Pires, N. M. and Gomes, P. (2022). Salt-inducible kinases: new players in pulmonary arterial hypertension? Trends Pharmacol Sci, 43 (10): 806-819. https://doi.org/10.1016/j.tips.2022.06.008
Bandeira, A., Albino-Teixeira, A. and Magina, S. (2022). Systematic review - alopecia areata and tofacitinib in paediatric patients. Cutan Ocul Toxicol, 41 (2): 194-201. https://doi.org/10.1080/15569527.2022.2084622
Carvalho, C. and Vieira-Coelho, M. A. (2022). Cannabis induced psychosis: A systematic review on the role of genetic polymorphisms. Pharmacol Res, 181 106258. https://doi.org/10.1016/j.phrs.2022.106258
Cerejeira, A., Canelas, G., Vide, J., Duro, R., Azevedo, F. and Magina, S. (2022). Cavitary pulmonary tuberculosis during treatment with guselkumab. J Eur Acad Dermatol Venereol, 36 (6): e488-e490. https://doi.org/10.1111/jdv.17992
Cerqueira, N., Neves, M., Rocha, J., Soares-da Silva, P. and Palma, P. N. (2022). Inactivation Mechanism of the Fatty Acid Amide Hydrolase Inhibitor BIA 10-2474. Chembiochem, 23 (20): e202200166. https://doi.org/10.1002/cbic.202200166
Chaudhuri, K. R., Odin, P., Ferreira, J. J., Antonini, A., Rascol, O., Kurtis, M. M., Storch, A., Bannister, K., Soares-da-Silva, P., Costa, R., Magalhaes, D. and Rocha, J. F. (2022). Opicapone versus placebo in the treatment of Parkinson's disease patients with end-of-dose motor fluctuation-associated pain: rationale and design of the randomised, double-blind OCEAN (OpiCapone Effect on motor fluctuations and pAiN) trial. BMC Neurol, 22 (1): 88. https://doi.org/10.1186/s12883-022-02602-8
Chavarria, D., Benfeito, S., Soares, P., Lima, C., Garrido, J., Serrao, P., Soares-da-Silva, P., Remiao, F., Oliveira, P. J. and Borges, F. (2022). Boosting caffeic acid performance as antioxidant and monoamine oxidase B/catechol-O-methyltransferase inhibitor. Eur J Med Chem, 243 114740. https://doi.org/10.1016/j.ejmech.2022.114740
Correia-Sa, I., Carvalho, C., V, A. M., Carvalho, S., Serrao, P., Marques, M. and Vieira-Coelho, M. A. (2022). Targeting cannabinoid receptor 2 (CB2) limits collagen production-An in vitro study in a primary culture of human fibroblasts. Fundam Clin Pharmacol, 36 (1): 89-99. https://doi.org/10.1111/fcp.12716
Cosme, D., Soares-da-Silva, P. and Magro, F. (2022). Effect of Toll-like receptor-2, -4, -5, -7, and NOD2 stimulation on potassium channel conductance in intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol, 323 (5): G410-G419. https://doi.org/10.1152/ajpgi.00139.2022
Cruz, D., Monteiro, F., Paco, M., Vaz-Silva, M., Lemos, C., Alves-Ferreira, M. and Pinho, T. (2022). Genetic overlap between temporomandibular disorders and primary headaches: A systematic review. Jpn Dent Sci Rev, 58 69-88. https://doi.org/10.1016/j.jdsr.2022.02.002
da Costa Azevedo, J. N., Carvalho, C., Serrao, M. P., Coelho, R., Figueiredo-Braga, M. and Vieira-Coelho, M. A. (2022). Catechol-O-methyltransferase activity in individuals with substance use disorders: a case control study. BMC Psychiatry, 22 (1): 412. https://doi.org/10.1186/s12888-022-04068-x
da Silva, M. T. B. and Dos Santos, A. A. (2022). Proinflammatory Effects of Wheat and Rye in an IBD Model: Give Us Not Our Daily Bread. Dig Dis Sci, 67 (9): 4324-4325. https://doi.org/10.1007/s10620-022-07466-z
Espanhol, J. C. L. and Vieira-Coelho, M. A. (2022). Effects of lithium use on the white matter of patients with bipolar disorder - a systematic review. Nord J Psychiatry, 76 (1): 1-11. https://doi.org/10.1080/08039488.2021.1921264
Farinha-Ferreira, M., Rei, N., Fonseca-Gomes, J., Miranda-Lourenco, C., Serrao, P., Vaz, S. H., Gomes, J. I., Martins, V., de Alves Pereira, B. and Sebastiao, A. M. (2022). Unexpected short- and long-term effects of chronic adolescent HU-210 exposure on emotional behavior. Neuropharmacology, 109155. https://doi.org/10.1016/j.neuropharm.2022.109155
Fernandes, H., Batalha, V., Braksator, E., Hebeisen, S., Bonifacio, M. J., Vieira-Coelho, M. A. and Soares-da-Silva, P. (2022). Voltage-clamp evidence of GABAA receptor subunit-specific effects: pharmacodynamic fingerprint of chlornordiazepam, the major active metabolite of mexazolam, as compared to alprazolam, bromazepam, and zolpidem. Pharmacol Rep, 74 (5): 956-968. https://doi.org/10.1007/s43440-022-00411-x
Ferreira, J. J., Poewe, W., Rascol, O., Stocchi, F., Antonini, A., Moreira, J., Guimaraes, B., Rocha, J. F. and Soares-da-Silva, P. (2022). Effect of Opicapone on Levodopa Pharmacokinetics in Patients with Fluctuating Parkinson's Disease. Mov Disord, 37 (11): 2272-2283. https://doi.org/10.1002/mds.29193
Figueiredo, A., Costa, L., Mauricio, M. J., Figueira, L., Ramos, R. and Martins-da-Silva, C. (2022). Nonmetastatic Castration-Resistant Prostate Cancer: Current Challenges and Trends. Clin Drug Investig, 42 (8): 631-642. https://doi.org/10.1007/s40261-022-01178-y
Gouveia, R., Cruz, V. T. and Almeida, L. (2022). Sociodemographic and psychological characteristics influencing patients' willingness to participate in clinical trials. BMJ Open Qual, 11 (4): https://doi.org/10.1136/bmjoq-2022-002044
Guerra Leal, B., Barros-Barbosa, A., Ferreirinha, F., Chaves, J., Rangel, R., Santos, A., Carvalho, C., Martins-Ferreira, R., Samoes, R., Freitas, J., Lopes, J., Ramalheira, J., Lobo, M. G., Martins da Silva, A., Costa, P. P. and Correia-de-Sa, P. (2022). Mesial Temporal Lobe Epilepsy (MTLE) Drug-Refractoriness Is Associated With P2X7 Receptors Overexpression in the Human Hippocampus and Temporal Neocortex and May Be Predicted by Low Circulating Levels of miR-22. Front Cell Neurosci, 16 910662. https://doi.org/10.3389/fncel.2022.910662
Herman-de-Sousa, C., Costa, M. A., Silva, R. P., Ferreirinha, F., Ribeiro, S. and Correia-de-Sa, P. (2022). A2A receptor-induced overexpression of pannexin-1 channels indirectly mediates adenosine fibrogenic actions by favouring ATP release from human subcutaneous fibroblasts. Life Sci, 310 121080. https://doi.org/10.1016/j.lfs.2022.121080
Jose-Vieira, R., Ferreira, A., Meneres, P., Sousa-Pinto, B. and Figueira, L. (2022). Efficacy and safety of intravitreal and periocular injection of corticosteroids in noninfectious uveitis: a systematic review. Surv Ophthalmol, 67 (4): 991-1013. https://doi.org/10.1016/j.survophthal.2021.12.002
Loureiro, A. I., Fernandes-Lopes, C., Bonifacio, M. J., Sousa, F., Kiss, L. E. and Soares-da-Silva, P. (2022). Metabolism and disposition of opicapone in the rat and metabolic enzymes phenotyping. Pharmacol Res Perspect, 10 (1): e00891. https://doi.org/10.1002/prp2.891
Loureiro, A. I., Rocha, F., Santos, A. T., Singh, N., Bonifacio, M. J., Pinto, R., Kiss, L. E. and Soares-da-Silva, P. (2022). Absorption, metabolism and excretion of opicapone in human healthy volunteers. Br J Clin Pharmacol, 88 (10): 4540-4551. https://doi.org/10.1111/bcp.15383
Martinho, R., Seixas, R., Azevedo, M., Oliveira, A., Serrao, P. and Moreira-Rodrigues, M. (2022). Sotalol Treatment may Interfere With Retrieval, Expression, and/or Reconsolidation Processes Thus Disrupting Traumatic Memories in a Post-Traumatic Stress Disorder Mice Model. Front Pharmacol, 12 809271. https://doi.org/10.3389/fphar.2021.809271
Martins, B., Miranda, J., Pinto, M. J., Costa, A., Silva-Pinto, A., Melo, N., Ceia, F., Costa, J. T. and Guimaraes, J. (2022). Common variable immunodeficiency and its inflammatory neurological manifestations: A case report and literature review. Mult Scler Relat Disord, 67 104086. https://doi.org/10.1016/j.msard.2022.104086
Martins, C., Moura, J., Figueiroa, S., Garrido, C., Martins, J., Samoes, R., Guimaraes, J., Melo, C., Sousa, R., Palavra, F., Ferreira, J., da Silva, A. M., Sa, M. J. and Santos, E. (2022). Pediatric neuromyelitis optica spectrum disorders in Portugal: A multicentre retrospective study. Mult Scler Relat Disord, 59 103531. https://doi.org/10.1016/j.msard.2022.103531
Martins, C. S. A., de Carvalho, J., Vaz da Silva, M. and Martins, L. (2022). The GENICA project - a prospective cohort of heart failure patients with a comprehensive ambulatory approach aiming better outcomes: study protocol. Ther Adv Cardiovasc Dis, 16 17539447221132908. https://doi.org/10.1177/17539447221132908
Monni, L., Kraus, L., Dipper-Wawra, M., Soares-da-Silva, P., Maier, N., Schmitz, D., Holtkamp, M. and Fidzinski, P. (2022). In vitro and in vivo anti-epileptic efficacy of eslicarbazepine acetate in a mouse model of KCNQ2-related self-limited epilepsy. Br J Pharmacol, 179 (1): 84-102. https://doi.org/10.1111/bph.15689
Moreira-Rodrigues, M. and Grubisha, M. J. (2022). Editorial: Molecular mechanisms of neuropsychiatric diseases. Front Mol Neurosci, 15 1102296. https://doi.org/10.3389/fnmol.2022.1102296
Reichmann, H., Eggert, K., Oehlwein, C., Warnecke, T., Lees, A. J., Kemmer, M. and Soares-da-Silva, P. (2022). Opicapone Use in Clinical Practice across Germany: A Sub-Analysis of the OPTIPARK Study in Parkinson's Disease Patients with Motor Fluctuations. Eur Neurol, 85 (5): 389-397. https://doi.org/10.1159/000523771
Reina-Couto, M., Santos-Oliveira, M., Pereira-Terra, P., Silva-Pereira, C., Quelhas-Santos, J., Duarte, A., Martins, S., Serrao, P., Dias, C. C., Morato, M., Guimaraes, J. T., Roncon-Albuquerque, R., Paiva, J. A., Albino-Teixeira, A. and Sousa, T. (2022). Urinary Cysteinyl Leukotrienes as Biomarkers of Endothelial Activation, Inflammation and Oxidative Stress and Their Relationship with Organ Dysfunction in Human Septic Shock. Biomedicines, 10 (11): https://doi.org/10.3390/biomedicines10112845
Reina-Couto, M., Silva-Pereira, C., Pereira-Terra, P., Quelhas-Santos, J., Bessa, J., Serrao, P., Afonso, J., Martins, S., Dias, C. C., Morato, M., Guimaraes, J. T., Roncon-Albuquerque, R., Paiva, J. A., Albino-Teixeira, A. and Sousa, T. (2022). Endothelitis profile in acute heart failure and cardiogenic shock patients: Endocan as a potential novel biomarker and putative therapeutic target. Front Physiol, 13 965611. https://doi.org/10.3389/fphys.2022.965611
Reis-Ferreira, A., Neto-Mendes, J., Bras-Silva, C., Lobo, L. and Fontes-Sousa, A. P. (2022). Emerging Roles of Micrornas in Veterinary Cardiology. Vet Sci, 9 (10): 533. https://doi.org/10.3390/vetsci9100533
Rocha, J. F., Santos, A., Gama, H., Moser, P., Falcao, A., Pressman, P., Wallace Hayes, A. and Soares-da-Silva, P. (2022). Safety, Tolerability, and Pharmacokinetics of FAAH Inhibitor BIA 10-2474: A Double-Blind, Randomized, Placebo-Controlled Study in Healthy Volunteers. Clin Pharmacol Ther, 111 (2): 391-403. https://doi.org/10.1002/cpt.2290
Schofield, C., Chaudhuri, K. R., Carroll, C., Sharma, J. C., Pavese, N., Evans, J., Foltynie, T., Reichmann, H., Zurowska, L., Soares-da-Silva, P. and Lees, A. (2022). Opicapone in UK clinical practice: effectiveness, safety and cost analysis in patients with Parkinson's disease. Neurodegener Dis Manag, 12 (2): 77-91. https://doi.org/10.2217/nmt-2021-0057
Teixeira, A., Ribeiro, C., Gaio, R., Torres, T., Magina, S., Pereira, T., Teixeira, M., Rocha, J. C., Lobo, J. M. S., Almeida, I. F., Vidal, D. G., Pedrosa, E. S. H. F., Dinis, M. A. P. and Almeida, V. (2022). Influence of psoriasis lesions' location and severity on psychosocial disability and psychopathology. Observational study and psychometric validation of the SAPASI Portuguese version. J Psychosom Res, 154 110714. https://doi.org/10.1016/j.jpsychores.2021.110714
Telles, P. V. N., Severo, J. S., de Oliveira, L. C. S., Reis, E. S. J. F., Cavalcante, A. K. M., da Silva, A. C. A., Aguiar Dos Santos, A. and Tolentino, M. (2022). Effect of anaerobic resistance training on gastric emptying of solids, nutritional parameters and food behavior in the rats treated with dexamethasone. Physiol Behav, 245 113674. https://doi.org/10.1016/j.physbeh.2021.113674
Vale, L., Charrua, A., Cavaleiro, H., Ribeiro-Oliveira, R., Avelino, A., Antunes-Lopes, T., Albino-Teixeira, A. and Cruz, F. (2022). DU Is Induced by Low Levels of Urinary ATP in a Rat Model of Partial Bladder Outlet Obstruction: The Incidence of Both Events Decreases after Deobstruction. Adv Urol, 2022 6292457. https://doi.org/10.1155/2022/6292457
Vasconcelos, I., Adao, R., Rademaker, M. T., Leite-Moreira, A. F., Fontes-Sousa, A. P. and Bras-Silva, C. (2022). Urocortins as biomarkers in cardiovascular disease. Clin Sci (Lond), 136 (1): 1-14. https://doi.org/10.1042/CS20210732
Vieira, R., Sousa-Pinto, B. and Figueira, L. (2022). Efficacy and Safety of Corticosteroid Implants in Non-infectious Uveitis: A Systematic Review with Network Meta-analysis. Ocul Immunol Inflamm, 30 (1): 215-222. https://doi.org/10.1080/09273948.2020.1787463

2021 (articles in alphabetic order)

Andermann, E., Rosenfeld, W., Penovich, P., Rogin, J., Cendes, F., Carreno, M., Ramsay, R. E., Ben-Menachem, E., Gama, H., Rocha, F., Soares-da-Silva, P., Tosiello, R., Blum, D. and Grinnell, T. (2021). Comparative analysis of the safety and tolerability of eslicarbazepine acetate in older (>/=60 years) and younger (18-59 years) adults. Epilepsy Res, 169 106478. https://doi.org/10.1016/j.eplepsyres.2020.106478
Antonio, T., Cosme, D., Igreja, B., Fraga, S., Serrao, M. P., Pires, N. M. and Soares-da-Silva, P. (2021). The role of salt-inducible kinases on the modulation of renal and intestinal Na(+),K(+)-ATPase activity during short- and long-term high-salt intake. Eur J Pharmacol, 904 174153. https://doi.org/10.1016/j.ejphar.2021.174153
Bonifacio, M. J., Sousa, F. and Soares-da-Silva, P. (2021). Opicapone enhances the reversal of MPTP-induced Parkinson-like syndrome by levodopa in cynomolgus monkeys. Eur J Pharmacol, 892 173742. https://doi.org/10.1016/j.ejphar.2020.173742
Borrega, R., Araujo, C., Aguiam, N., Magro, F., Fonseca, J. E., Danese, S., Lopes, J. and Goncalves, J. (2021). Systematic Review and Principal Components Analysis of the Immunogenicity of Adalimumab. BioDrugs, 35 (1): 35-45. https://doi.org/10.1007/s40259-020-00458-3
Campos-Martins, A., Braganca, B., Correia-de-Sa, P. and Fontes-Sousa, A. P. (2021). Pharmacological Tuning of Adenosine Signal Nuances Underlying Heart Failure With Preserved Ejection Fraction. Front Pharmacol, 12 724320. https://doi.org/10.3389/fphar.2021.724320
Carrola, G., Lima-Fontes, M., Falcao-Reis, F., Figueira, L. and Carneiro, A. (2021). Inflammatory Choroidal Neovascular Membranes: Clinical Profile, Treatment Effectiveness, and Visual Prognosis. J Ophthalmol, 2021 9982883. https://doi.org/10.1155/2021/9982883
Charbit-Henrion, F., Parlato, M., Hanein, S., Duclaux-Loras, R., Nowak, J., Begue, B., Rakotobe, S., Bruneau, J., Fourrage, C., Alibeu, O., Rieux-Laucat, F., Levy, E., Stolzenberg, M. C., Mazerolles, F., Latour, S., Lenoir, C., Fischer, A., Picard, C., Aloi, M., Dias, J. A., Hariz, M. B., Bourrier, A., Breuer, C., Breton, A., Bronsky, J., Buderus, S., Cananzi, M., Coopman, S., Cremilleux, C., Dabadie, A., Dumant-Forest, C., Gurkan, O. E., Fabre, A., Fischer, A., Diaz, M. G., Gonzalez-Lama, Y., Goulet, O., Guariso, G., Gurcan, N., Homan, M., Hugot, J. P., Jeziorski, E., Karanika, E., Lachaux, A., Lewindon, P., Lima, R., Magro, F., Major, J., Malamut, G., Mas, E., Mattyus, I., Mearin, L. M., Melek, J., Navas-Lopez, V. M., Paerregaard, A., Pelatan, C., Pigneur, B., Pais, I. P., Rebeuh, J., Romano, C., Siala, N., Strisciuglio, C., Tempia-Caliera, M., Tounian, P., Turner, D., Urbonas, V., Willot, S., Ruemmele, F. M. and Cerf-Bensussan, N. (2021). Corrigendum to: Diagnostic Yield of Next-Generation Sequencing in Very Early-Onset Inflammatory Bowel Diseases: A Multicenter Study. J Crohns Colitis, 15 (3): 517-518. https://doi.org/10.1093/ecco-jcc/jjaa164
Correia-Sa, I. B., Carvalho, C. M., Serrao, P. V., Machado, V. A., Carvalho, S. O., Marques, M. and Vieira-Coelho, M. A. (2021). AM251, a cannabinoid receptor 1 antagonist, prevents human fibroblasts differentiation and collagen deposition induced by TGF-beta - An in vitro study. Eur J Pharmacol, 892 173738. https://doi.org/10.1016/j.ejphar.2020.173738
Cosme, D., Estevinho, M. M., Rieder, F. and Magro, F. (2021). Potassium channels in intestinal epithelial cells and their pharmacological modulation: a systematic review. Am J Physiol Cell Physiol, 320 (4): C520-C546. https://doi.org/10.1152/ajpcell.00393.2020
Costa, R., Martins, A., Guimaraes, J. and Costa, A. (2021). Sneddon syndrome: a rare cause of stroke hidden in plain sight. Acta Neurol Belg, in press https://doi.org/10.1007/s13760-021-01839-3
Cunha, A. M., Silva, M., Pedrosa, A. C., Falcao-Reis, F. and Figueira, L. (2021). Nocardia Subretinal Abscess: A Rare and Challenging Case Report. Case Rep Ophthalmol Med, 2021 8876864. https://doi.org/10.1155/2021/8876864
Cunha-Reis, D., Caulino-Rocha, A. and Correia-de-Sa, P. (2021). VIPergic neuroprotection in epileptogenesis: challenges and opportunities. Pharmacol Res, 164 105356. https://doi.org/10.1016/j.phrs.2020.105356
D'Amico, F., Solitano, V., Aletaha, D., Hart, A., Magro, F., Selmi, C., Ng, S. C., Al Awadhi, S., Choy, E., Schulze-Koops, H., Bossuyt, P., Olivera, P. A., Kotze, P. G., Ghosh, S., Peyrin-Biroulet, L. and Danese, S. (2021). Biobetters in patients with immune-mediated inflammatory disorders: An international Delphi consensus. Autoimmun Rev, 20 (7): 102849. https://doi.org/10.1016/j.autrev.2021.102849
Fernandes, S., Sosa-Napolskij, M., Lobo, G. and Silva, I. (2021). Impact of the COVID-19 pandemic in the Portuguese population: Consumption of alcohol, stimulant drinks, illegal substances, and pharmaceuticals. PLoS One, 16 (11): e0260322. https://doi.org/10.1371/journal.pone.0260322
Ferreira-Duarte, M., Rodrigues-Pinto, T., Menezes-Pinto, D., Esteves-Monteiro, M., Goncalves-Monteiro, S., Capas-Peneda, S., Magro, F., Dias-Pereira, P., Morato, M. and Duarte-Araujo, M. (2021). 2,4,6-trinitrobenzenesulfonic acid-induced colitis in Rattus norgevicus: a categorization proposal. Exp Anim, 70 (2): 245-256. https://doi.org/10.1538/expanim.20-0113
Ferreira-Duarte, M., Rodrigues-Pinto, T., Sousa, T., Faria, M. A., Rocha, M. S., Menezes-Pinto, D., Esteves-Monteiro, M., Magro, F., Dias-Pereira, P., Duarte-Araujo, M. and Morato, M. (2021). Interaction between the Renin-Angiotensin System and Enteric Neurotransmission Contributes to Colonic Dysmotility in the TNBS-Induced Model of Colitis. Int J Mol Sci, 22 (9): https://doi.org/10.3390/ijms22094836
Fiorino, G., Estevinho, M. M., Lopes, D. J. M., Chersi, F., Allocca, M., Souto, M. T., Danese, S. and Magro, F. (2021). Inflammatory Bowel Disease in Migrant Populations: Should we Look Even Further Back? Curr Drug Targets, 22 (15): 1706-1715. https://doi.org/10.2174/1389450122666210203193817
Gomez Rivas, J., Somani, B., Rodriguez Socarras, M., Marra, G., Pearce, I., Henningsohn, L., Zondervan, P., van der Poel, H., Van Poppel, H., N'Dow, J., Liatsikos, E., Palou, J. and a European School of Urology collaborative, g. (2021). Essentials for Standardising the Undergraduate Urology Curriculum in Europe: Outcomes of a Delphi Consensus from the European School of Urology. Eur Urol Open Sci, 33 72-80. https://doi.org/10.1016/j.euros.2021.09.003
Goncalo, A. M. G. and Vieira-Coelho, M. A. (2021). The effects of trazodone on human cognition: a systematic review. Eur J Clin Pharmacol, 77 (11): 1623-1637. https://doi.org/10.1007/s00228-021-03161-6
Hayes, A. W., Weber, K., Moser, P. and Soares-da-Silva, P. (2021). Non-clinical toxicology evaluation of BIA 10-2474. Crit Rev Toxicol, 51 (1): 65-75. https://doi.org/10.1080/10408444.2020.1867821
Hermann, L., Falcao-Reis, F. and Figueira, L. (2021). Epidemiology of Uveitis in a tertiary care centre in Portugal. Semin Ophthalmol, 36 (1-2): 51-57. https://doi.org/10.1080/08820538.2021.1885721
Jenner, P., Rocha, J. F., Ferreira, J. J., Rascol, O. and Soares-da-Silva, P. (2021). Redefining the strategy for the use of COMT inhibitors in Parkinson's disease: the role of opicapone. Expert Rev Neurother, 21 (9): 1019-1033. https://doi.org/10.1080/14737175.2021.1968298
Kucharzik, T., Ellul, P., Greuter, T., Rahier, J. F., Verstockt, B., Abreu, C., Albuquerque, A., Allocca, M., Esteve, M., Farraye, F. A., Gordon, H., Karmiris, K., Kopylov, U., Kirchgesner, J., MacMahon, E., Magro, F., Maaser, C., de Ridder, L., Taxonera, C., Toruner, M., Tremblay, L., Scharl, M., Viget, N., Zabana, Y. and Vavricka, S. (2021). ECCO Guidelines on the Prevention, Diagnosis, and Management of Infections in Inflammatory Bowel Disease. J Crohns Colitis, 15 (6): 879-913. https://doi.org/10.1093/ecco-jcc/jjab052
Leite-Almeida, L., Morato, M., Cosme, D., Afonso, J., Areias, J. C., Guerra, A., Caldas Afonso, A., Albino-Teixeira, A., Sousa, T. and Correia-Costa, L. (2021). Impact of physical activity on redox status and nitric oxide bioavailability in nonoverweight and overweight/obese prepubertal children. Free Radic Biol Med, 163 116-124. https://doi.org/10.1016/j.freeradbiomed.2020.12.005
Leuzinger-Dias, M., Godinho, G., Lima-Fontes, M., Oliveira-Ferreira, C., Camisa, E., Falcao-Reis, F., Silva, M. and Figueira, L. (2021). A painful red eye in an intravenous drug abuser: When not everything is what it seems. Eur J Ophthalmol, 11206721211060151. https://doi.org/10.1177/11206721211060151
Lobo, L., Esteves-Guimaraes, J., Oliveira, P., Salazar, L., Pereira, A. and Fontes-Sousa, A. P. (2021). Maternal Left Ventricular Diastolic and Systolic Function during Normal Pregnancy in Saint Bernard Dogs. Vet Sci, 8 (12): https://doi.org/10.3390/vetsci8120306
Magalhaes, L. M., Costa, R., Vieira, M., Moreira, J., Gama, H. and Soares-da-Silva, P. (2021). Safety of Eslicarbazepine Acetate in Elderly Versus Non-Elderly Patients with Focal Seizures: From Pooled Data of Clinical Studies to 8 Years of Post-Marketing Experience. Drug Saf, 44 (10): 1099-1107. https://doi.org/10.1007/s40264-021-01097-5
Magina, S. and Filipe, P. (2021). Pathophysiology of moderate to severe plaque psoriasis: anti-IL-17 towards disease modification. Drugs Today (Barc), 57 (5): 347-357. https://doi.org/10.1358/dot.2021.57.5.3266244
Magro, F., Dias, C. C. and Morato, M. (2021). Aminosalicylates and COVID-19: Facts or Coincidences? Gastroenterology, 160 (5): 1884-1885. https://doi.org/10.1053/j.gastro.2020.05.092
Magro, F., Estevinho, M. M., Dias, C. C., Correia, L., Lago, P., Ministro, P., Portela, F., Feakins, R., Danese, S. and Peyrin-Biroulet, L. (2021). Clinical, Endoscopic and Histological Outcomes in Induction of Moderate-to-Severe Ulcerative Colitis: A Systematic Review with Meta-Analysis. J Crohns Colitis, 15 (4): 551-566. https://doi.org/10.1093/ecco-jcc/jjaa176
Magro, F., Nuzzo, A., Abreu, C., Libanio, D., Rodriguez-Lago, I., Pawlak, K., Hollenbach, M., Brouwer, W. P. and Siau, K. (2021). COVID-19 in gastroenterology: Where are we now? Current evidence on the impact of COVID-19 in gastroenterology. United European Gastroenterol J, 9 (7): 750-765. https://doi.org/10.1002/ueg2.12115
Malheiro, L. F., Gaio, R., Vaz da Silva, M., Martins, S., Sarmento, A. and Santos, L. (2021). Peripheral arterial tonometry as a method of measuring reactive hyperaemia correlates with organ dysfunction and prognosis in the critically ill patient: a prospective observational study. J Clin Monit Comput, 35 (5): 1169-1181. https://doi.org/10.1007/s10877-020-00586-9
Martinho, R., Correia, G., Seixas, R., Oliveira, A., Silva, S., Serrao, P., Fernandes-Lopes, C., Costa, C. and Moreira-Rodrigues, M. (2021). Treatment With Nepicastat Decreases Contextual Traumatic Memories Persistence in Post-traumatic Stress Disorder. Front Mol Neurosci, 14 745219. https://doi.org/10.3389/fnmol.2021.745219
Martins, C., Machado da Silva, J., Guimaraes, D., Martins, L. and Vaz Da Silva, M. (2021). MONITORIA: The start of a new era of ambulatory heart failure monitoring? Part II - Design. Rev Port Cardiol (Engl Ed), 40 (5): 343-351. https://doi.org/10.1016/j.repce.2020.07.019
Martins, C., Machado da Silva, J., Guimaraes, D., Martins, L. and Vaz da Silva, M. (2021). MONITORIA: The start of a new era of ambulatory heart failure monitoring? Part I - Theoretical Rationale. Rev Port Cardiol (Engl Ed), 40 (5): 329-337. https://doi.org/10.1016/j.repce.2020.07.018
Melo, F. J., Pinto-Lopes, P., Estevinho, M. M. and Magro, F. (2021). The Role of Dipeptidyl Peptidase 4 as a Therapeutic Target and Serum Biomarker in Inflammatory Bowel Disease: A Systematic Review. Inflamm Bowel Dis, 27 (7): 1153-1165. https://doi.org/10.1093/ibd/izaa324
Mendes-Bastos, P., Nero, P., Ferreira, P., Bernardo, A., Barcelos, A., Pimentel Dos Santos, F. M., Sousa, J., Loureiro, M. M., Magina, S., Alpalhao, M., Antunes, J. and Vieira-Sousa, E. (2021). A multidisciplinary approach in psoriatic disease: the different models of dermatology-rheumatology collaborations in Portugal. Acta Reumatol Port, 46 (4): 333-341.
Miehlke, S., Guagnozzi, D., Zabana, Y., Tontini, G. E., Kanstrup Fiehn, A. M., Wildt, S., Bohr, J., Bonderup, O., Bouma, G., D'Amato, M., Heiberg Engel, P. J., Fernandez-Banares, F., Macaigne, G., Hjortswang, H., Hultgren-Hornquist, E., Koulaouzidis, A., Kupcinskas, J., Landolfi, S., Latella, G., Lucendo, A., Lyutakov, I., Madisch, A., Magro, F., Marlicz, W., Mihaly, E., Munck, L. K., Ostvik, A. E., Patai, A. V., Penchev, P., Skonieczna-Zydecka, K., Verhaegh, B. and Munch, A. (2021). European guidelines on microscopic colitis: United European Gastroenterology and European Microscopic Colitis Group statements and recommendations. United European Gastroenterol J, 9 (1): 13-37. https://doi.org/10.1177/2050640620951905
Ministro, P., Dias, C. C., Portela, F., Fernandes, S., Bernardo, S., Pires, F., Lago, P., Rosa, I., Trindade, E., Alves, C., Correia, L. and Magro, F. (2021). Age at Diagnosis Is Determinant for the Outcome of Inflammatory Bowel Disease: Is It a Myth?Clin Transl Gastroenterol, 12 (2): e00309. https://doi.org/10.14309/ctg.0000000000000309
Moleiro, A. F., Aires, A. F., Alves, H., Viana Pinto, J., Carneiro, A., Falcao-Reis, F., Figueira, L. and Pinheiro-Costa, J. (2021). The Role of Atopy in the Choroidal Profile of Keratoconus Patients. Clin Ophthalmol, 15 1799-1807. https://doi.org/10.2147/OPTH.S301330
Pinho, S., Rocha, V. and Vieira-Coelho, M. A. (2021). Effectiveness of multimodal interventions focused on smoking cessation in patients with schizophrenia: A systematic review. Schizophr Res, 231 145-153. https://doi.org/10.1016/j.schres.2021.03.012
Pinto-Lopes, P., Melo, F., Afonso, J., Pinto-Lopes, R., Rocha, C., Melo, D., Macedo, G., Dias, C. C., Carneiro, F., Magro, F. and Portuguese, I. B. D. S. G. (2021). Fecal Dipeptidyl Peptidase-4: An Emergent Biomarker in Inflammatory Bowel Disease. Clin Transl Gastroenterol, 12 (3): e00320. https://doi.org/10.14309/ctg.0000000000000320
Pires, N. M., Igreja, B. and Soares-da-Silva, P. (2021). Antagonistic modulation of SIK1 and SIK2 isoforms in high blood pressure and cardiac hypertrophy triggered by high-salt intake. Clin Exp Hypertens, 43 (5): 428-435. https://doi.org/10.1080/10641963.2021.1896728
Reina-Couto, M., Afonso, J., Carvalho, J., Morgado, L., Ronchi, F. A., de Oliveira Leite, A. P., Dias, C. C., Casarini, D. E., Bettencourt, P., Albino-Teixeira, A., Morato, M. and Sousa, T. (2021). Interrelationship between renin-angiotensin-aldosterone system and oxidative stress in chronic heart failure patients with or without renal impairment. Biomed Pharmacother, 133 110938. https://doi.org/10.1016/j.biopha.2020.110938
Reina-Couto, M., Pereira-Terra, P., Quelhas-Santos, J., Silva-Pereira, C., Albino-Teixeira, A. and Sousa, T. (2021). Inflammation in Human Heart Failure: Major Mediators and Therapeutic Targets. Front Physiol, 12 746494. https://doi.org/10.3389/fphys.2021.746494
Rocha, J. F., Ebersbach, G., Lees, A., Tolosa, E., Ferreira, J. J., Poewe, W., Rascol, O., Stocchi, F., Antonini, A., Magalhaes, D., Gama, H. and Soares-da-Silva, P. (2021). The Added Benefit of Opicapone When Used Early in Parkinson's Disease Patients With Levodopa-Induced Motor Fluctuations: A Post-hoc Analysis of BIPARK-I and -II. Front Neurol, 12 754016. https://doi.org/10.3389/fneur.2021.754016
Roseira, J., Sousa, H. T., Marreiros, A., Contente, L. F. and Magro, F. (2021). Short Inflammatory Bowel Disease Questionnaire: translation and validation to the Portuguese language. Health Qual Life Outcomes, 19 (1): 59. https://doi.org/10.1186/s12955-021-01698-9
Schmidt, S., Pothmann, L., Muller-Komorowska, D., Opitz, T., Soares da Silva, P. and Beck, H. (2021). Complex effects of eslicarbazepine on inhibitory micro networks in chronic experimental epilepsy. Epilepsia, 62 (2): 542-556. https://doi.org/10.1111/epi.16808
Sousa, P., Ministro, P., Armuzzi, A., Dignass, A., Hoivik, M. L., Barreiro-de Acosta, M., Vavricka, S., Saad-Hossne, R., Kotze, P. G., Peyrin-Biroulet, L. and Magro, F. (2021). Thiopurines: Use them or lose them? International survey on current and future use of thiopurines in inflammatory bowel disease. Dig Liver Dis, 53 (12): 1571-1579. https://doi.org/10.1016/j.dld.2021.05.038
Tavares de Sousa, H., Gullo, I., Castelli, C., Dias, C. C., Rieder, F., Carneiro, F. and Magro, F. (2021). Ileal Crohn's Disease Exhibits Similar Transmural Fibrosis Irrespective of Phenotype. Clin Transl Gastroenterol, 12 (4): e00330. https://doi.org/10.14309/ctg.0000000000000330
Tavares, M., Farraia, M., Silva, S., Ribeiro, A. M., Severo, M., Paciencia, I., Ribeiro, R., Hespanhol, V., Guimaraes, T., Almeida, J., Magro, F., Sarmento, A., Oliveira, A. M. and Moreira, A. (2021). Impact of montelukast as add on treatment to the novel coronavirus pneumonia (COVID-19): protocol for an investigator-initiated open labeled randomized controlled pragmatic trial. Porto Biomed J, 6 (2): e134. https://doi.org/10.1097/j.pbj.0000000000000134
Teixeira, A., Teixeira, M., Almeida, V., Gaio, R., Torres, T., Magina, S., Cunha, C., Sousa Lobo, J. M. and Almeida, I. F. (2021). Does the Vehicle Matter? Real-World Evidence on Adherence to Topical Treatment in Psoriasis. Pharmaceutics, 13 (10): https://doi.org/10.3390/pharmaceutics13101539
Teixeira-Santos, L., Albino-Teixeira, A. and Pinho, D. (2021). An alternative method for oral drug administration by voluntary intake in male and female mice. Lab Anim, 55 (1): 76-80. https://doi.org/10.1177/0023677220950782
Ungar, B., Malickova, K., Hanzel, J., Abu Arisha, M., Paul, S., Rocha, C., Ben Shatach, Z., Abitbol, C. M., Haj Natour, O., Selinger, L., Yavzori, M., Fudim, E., Picard, O., Shoval, I., Eliakim, R., Kopylov, U., Magro, F., Roblin, X., Chowers, Y., Drobne, D., Lukas, M. and Ben Horin, S. (2021). Dose optimisation for Loss of Response to Vedolizumab- Pharmacokinetics and Immune Mechanisms. J Crohns Colitis, 15 (10): 1707-1719. https://doi.org/10.1093/ecco-jcc/jjab067
Vieira, R., Sousa-Pinto, B. and Figueira, L. (2021). Beware of word truncation in PubMed: unexpected problems and potential solutions. BMJ Evid Based Med, 26 (1): 34-36. https://doi.org/10.1136/bmjebm-2019-111286

2020 (articles in alphabetic order)

Alves, J. M., Seabra, M., Braz, L. and Guimaraes, J. (2020). Optic neuropathy: A 15-year retrospective observational study. Mult Scler Relat Disord, 44 102337. https://doi.org/10.1016/j.msard.2020.102337
Azevedo, J., Vieira-Coelho, M., Castelo-Branco, M., Coelho, R. and Figueiredo-Braga, M. (2020). Impulsive and premeditated aggression in male offenders with antisocial personality disorder. PLoS One, 15 (3): e0229876. https://doi.org/10.1371/journal.pone.0229876
Barbosa, R. S. D. and Vieira-Coelho, M. A. (2020). Probiotics and prebiotics: focus on psychiatric disorders - a systematic review. Nutr Rev, 78 (6): 437-450. https://doi.org/10.1093/nutrit/nuz080
Bessa, J., Albino-Teixeira, A., Reina-Couto, M. and Sousa, T. (2020). Endocan: A novel biomarker for risk stratification, prognosis and therapeutic monitoring in human cardiovascular and renal diseases. Clin Chim Acta, 509 310-335. https://doi.org/10.1016/j.cca.2020.07.041
Bonifacio, M. J., Sousa, F., Aires, C., Loureiro, A. I., Fernandes-Lopes, C., Pires, N. M., Palma, P. N., Moser, P. and Soares-da-Silva, P. (2020). Preclinical pharmacological evaluation of the fatty acid amide hydrolase inhibitor BIA 10-2474. Br J Pharmacol, 177 (9): 2123-2142. https://doi.org/10.1111/bph.14973
Braganca, B. and Correia-de-Sa, P. (2020). Resolving the Ionotropic P2X4 Receptor Mystery Points Towards a New Therapeutic Target for Cardiovascular Diseases. Int J Mol Sci, 21 (14): https://doi.org/10.3390/ijms21145005
Catelas, D. N., Serrao, M. P. and Soares-Da-Silva, P. (2020). Effects of nepicastat upon dopamine-beta-hydroxylase activity and dopamine and norepinephrine levels in the rat left ventricle, kidney, and adrenal gland. Clin Exp Hypertens, 42 (2): 118-125. https://doi.org/10.1080/10641963.2019.1583245
Chaves, C. B. and Vieira-Coelho, M. A. (2020). Clinical trials with monoclonal antibodies in schizophrenia. Schizophr Res, 222 511-513. https://doi.org/10.1016/j.schres.2020.05.026
Correia-Sa, I., Paiva, A., Carvalho, C. M. and Vieira-Coelho, M. A. (2020). Cutaneous endocannabinoid system: Does it have a role on skin wound healing bearing fibrosis?Pharmacol Res, 159 104862. https://doi.org/10.1016/j.phrs.2020.104862
Correia-Sa, I. B., Carvalho, C. M., Serrao, P. V., Loureiro, A. I., Fernandes-Lopes, C., Marques, M. and Vieira-Coelho, M. A. (2020). A new role for anandamide: defective link between the systemic and skin endocannabinoid systems in hypertrophic human wound healing. Sci Rep, 10 (1): 11134. https://doi.org/10.1038/s41598-020-68058-3
Costa-Pereira, J. T., Serrao, P., Martins, I. and Tavares, I. (2020). Serotoninergic pain modulation from the rostral ventromedial medulla (RVM) in chemotherapy-induced neuropathy: The role of spinal 5-HT3 receptors. Eur J Neurosci, 51 (8): 1756-1769. https://doi.org/10.1111/ejn.14614
D'Amico, F., Pouillon, L., Argollo, M., Hart, A., Fiorino, G., Vegni, E., Radice, S., Gilardi, D., Fazio, M., Leone, S., Bonovas, S., Magro, F., Danese, S. and Peyrin-Biroulet, L. (2020). Multidisciplinary management of the nocebo effect in biosimilar-treated IBD patients: Results of a workshop from the NOCE-BIO consensus group. Dig Liver Dis, 52 (2): 138-142. https://doi.org/10.1016/j.dld.2019.11.004
de Oliveira, M., Mathias, L. S., de Sibio, M. T., Noronha-Matos, J. B., Costa, M. A., Nogueira, C. R. and Correia-de-Sa, P. (2020). Pitfalls and challenges of the purinergic signaling cascade in obesity. Biochem Pharmacol, 182 114214. https://doi.org/10.1016/j.bcp.2020.114214
Dias, A. M., Cordeiro, G., Estevinho, M. M., Veiga, R., Figueira, L., Reina-Couto, M., Magro, F. and the Clinical Pharmacology Unit, S. J. H. U. C. (2020). Gut bacterial microbiome composition and statin intake-A systematic review. Pharmacol Res Perspect, 8 (3): e00601. https://doi.org/10.1002/prp2.601
Estevinho, M. M., Rocha, C., Correia, L., Lago, P., Ministro, P., Portela, F., Trindade, E., Afonso, J., Peyrin-Biroulet, L., Magro, F. and Gedii (2020). Features of Fecal and Colon Microbiomes Associate With Responses to Biologic Therapies for Inflammatory Bowel Diseases: A Systematic Review. Clin Gastroenterol Hepatol, 18 (5): 1054-1069. https://doi.org/10.1016/j.cgh.2019.08.063
Ferreira-Duarte, M., Sousa, J. B., Diniz, C., Sousa, T., Duarte-Araujo, M. and Morato, M. (2020). Experimental and Clinical Evidence of Endothelial Dysfunction in Inflammatory Bowel Disease. Curr Pharm Des, 26 (30): 3733-3747. https://doi.org/10.2174/1381612826666200701212414
Gomes, N., Sibaud, V., Azevedo, F. and Magina, S. (2020). [Cutaneous Toxicity of Immune Checkpoint Inhibitors: A Narrative Review]. Acta Med Port, 33 (5): 335-343. https://doi.org/10.20344/amp.12424
Guiomar, N., Vaz-da-Silva, M., Mbala, D., Sousa-Pinto, B., Monteiro, J. P., Ponce, P., Carneiro, F., Guerra, M., Neves, F., Ferraz, R., Rijo, D., Teixeira, M., Vouga, L. and Braga, P. (2020). Cardiac surgery in infective endocarditis and predictors of in-hospital mortality. Rev Port Cardiol (Engl Ed), 39 (3): 137-149. https://doi.org/10.1016/j.repc.2019.08.009
Hayes, A. W., Pressman, P., Moser, P. and Soares-da-Silva, P. (2020). Regulatory safety pharmacology evaluation of BIA 10-2474. J Pharmacol Toxicol Methods, 102 106677. https://doi.org/10.1016/j.vascn.2020.106677
Herman-de-Sousa, C., Pinheiro, A. R., Paramos-de-Carvalho, D., Costa, M. A., Ferreirinha, F., Magalhaes-Cardoso, T., Ribeiro, S., Pelletier, J., Sevigny, J. and Correia-de-Sa, P. (2020). Opposing Effects of Adenosine and Inosine in Human Subcutaneous Fibroblasts May Be Regulated by Third Party ADA Cell Providers. Cells, 9 (3): https://doi.org/10.3390/cells9030651
Kirkham, F., Auvin, S., Moreira, J., Gama, H., Falcao, A. C., Rocha, J. F. and Soares-da-Silva, P. (2020). Efficacy and safety of eslicarbazepine acetate as adjunctive therapy for refractory focal-onset seizures in children: A double-blind, randomized, placebo-controlled, parallel-group, multicenter, phase-III clinical trial. Epilepsy Behav, 105 106962. https://doi.org/10.1016/j.yebeh.2020.106962
Magro, F., Lopes, J., Borralho, P., Lopes, S., Coelho, R., Cotter, J., Dias de Castro, F., Tavares de Sousa, H., Salgado, M., Andrade, P., Vieira, A. I., Figueiredo, P., Caldeira, P., Sousa, A., Duarte, M. A., Avila, F., Silva, J., Moleiro, J., Mendes, S., Giestas, S., Ministro, P., Sousa, P., Goncalves, R., Goncalves, B., Oliveira, A., Chagas, C., Cravo, M., Dias, C. C., Afonso, J., Portela, F., Santiago, M., Geboes, K. and Carneiro, F. (2020). Comparing the Continuous Geboes Score With the Robarts Histopathology Index: Definitions of Histological Remission and Response and their Relation to Faecal Calprotectin Levels. J Crohns Colitis, 14 (2): 169-175. https://doi.org/10.1093/ecco-jcc/jjz123
Martinho, R., Oliveira, A., Correia, G., Marques, M., Seixas, R., Serrao, P. and Moreira-Rodrigues, M. (2020). Epinephrine May Contribute to the Persistence of Traumatic Memories in a Post-traumatic Stress Disorder Animal Model. Front Mol Neurosci, 13 588802. https://doi.org/10.3389/fnmol.2020.588802
Miranda-Lourenco, C., Duarte, S. T., Palminha, C., Gaspar, C., Rodrigues, T. M., Magalhaes-Cardoso, T., Rei, N., Colino-Oliveira, M., Gomes, R., Ferreira, S., Rosa, J., Xapelli, S., Armstrong, J., Garcia-Cazorla, A., Correia-de-Sa, P., Sebastiao, A. M. and Diogenes, M. J. (2020). Impairment of adenosinergic system in Rett syndrome: Novel therapeutic target to boost BDNF signalling. Neurobiol Dis, 145 105043. https://doi.org/10.1016/j.nbd.2020.105043
Neiva, R., Caulino-Rocha, A., Ferreirinha, F., Lobo, M. G. and Correia-de-Sa, P. (2020). Non-genomic Actions of Methylprednisolone Differentially Influence GABA and Glutamate Release From Isolated Nerve Terminals of the Rat Hippocampus. Front Mol Neurosci, 13 146. https://doi.org/10.3389/fnmol.2020.00146
Noronha-Matos, J. B., Oliveira, L., Peixoto, A. R., Almeida, L., Castellao-Santana, L. M., Ambiel, C. R., Alves-do Prado, W. and Correia-de-Sa, P. (2020). Nicotinic alpha7 receptor-induced adenosine release from perisynaptic Schwann cells controls acetylcholine spillover from motor endplates. J Neurochem, 154 (3): 263-283. https://doi.org/10.1111/jnc.14975
Nunes-Carneiro, D., Madanelo, M., Silva, F., Pestana, N., Ribeiro, C., Gil-Sousa, D., Martins, S., Almeida, M., Dias, L., Malheiro, J., Cavadas, V., Castro-Henriques, A., Fraga, A. and Silva-Ramos, M. (2020). Remaining kidney volume indexed to weight as a strong predictor of estimated glomerular filtration rate at 1 year and mid-term renal function after living-donor nephrectomy - a retrospective observational study. Transpl Int, 33 (10): 1262-1273. https://doi.org/10.1111/tri.13683
Patinha, D., Abreu, C., Carvalho, C., Cunha, O. M., Mota, M., Afonso, J., Sousa, T., Albino-Teixeira, A., Diniz, C. and Morato, M. (2020). Adenosine A2A and A3 Receptors as Targets for the Treatment of Hypertensive-Diabetic Nephropathy. Biomedicines, 8 (11): https://doi.org/10.3390/biomedicines8110529
Pinto-Cardoso, R., Pereira-Costa, F., Pedro Faria, J., Bandarrinha, P., Bessa-Andres, C., Correia-de-Sa, P. and Bernardo Noronha-Matos, J. (2020). Adenosinergic signalling in chondrogenesis and cartilage homeostasis: Friend or foe?Biochem Pharmacol, 174 113784. https://doi.org/10.1016/j.bcp.2019.113784
Portela, F., Ministro, P., de Deus, J., Cravo, M., Cotter, J., Duque, G., Ferreira, F., Rosa, B., Ferreira, P. L., Dias, C. C., Magro, F. and Portuguese, I. B. D. S. G. (2020). Health-Related Quality of Life in Patients with Moderate to Severe Ulcerative Colitis: Surgical Intervention versus Immunomodulatory Therapy. Digestion, 101 (5): 631-637. https://doi.org/10.1159/000501823
Reichmann, H., Lees, A., Rocha, J. F., Magalhaes, D., Soares-da-Silva, P. and investigators, O. (2020). Correction to: Effectiveness and safety of opicapone in Parkinson's disease patients with motor fluctuations: the OPTIPARK open-label study. Transl Neurodegener, 9 (1): 14. https://doi.org/10.1186/s40035-020-00193-3
Reichmann, H., Lees, A., Rocha, J. F., Magalhaes, D., Soares-da-Silva, P. and investigators, O. (2020). Effectiveness and safety of opicapone in Parkinson's disease patients with motor fluctuations: the OPTIPARK open-label study. Transl Neurodegener, 9 9. https://doi.org/10.1186/s40035-020-00187-1
Rogin, J., Resnick, T., Strom, L., Ben-Menachem, E., Kochen, S., Blum, D., Gama, H., Soares-da-Silva, P., Li, Y. and Grinnell, T. (2020). Analysis of cutaneous allergic reactions in clinical trials of eslicarbazepine acetate. Acta Neurol Scand, 141 (5): 397-404. https://doi.org/10.1111/ane.13218
Salmanton-Garcia, J., Koehler, P., Kindo, A., Falces-Romero, I., Garcia-Rodriguez, J., Racil, Z., Chen, S. C., Klimko, N., Desoubeaux, G., Thompson Gr, III, Benitez-Penuela, M. A., Rodriguez, J. Y., Sheppard, D. C., Hoenigl, M., Le Govic, Y., Badali, H., Baddley, J. W., Chander, J., Ingram, P. R., Pakstis, D. L., Mellinghoff, S. C., Atici, S., Cesaro, S., Chakrabarti, A., Dupont, D., Gonzalez, G. M., Hatvani, L., Herbrecht, R., Klyasova, G., Lass-Florl, C., Mares, M., Mullane, K., Vinh, D. C., Wisplinghoff, H., Lackner, M., Cornely, O. A., Seidel, D. and group, E. I. w. (2020). Needles in a haystack: Extremely rare invasive fungal infections reported in FungiScope(Ⓡ)-Global Registry for Emerging Fungal Infections. J Infect, 81 (5): 802-815. https://doi.org/10.1016/j.jinf.2020.08.015
Silva, F., Malheiro, J., Pestana, N., Ribeiro, C., Nunes-Carneiro, D., Mandanelo, M., Tavares, J., Pedroso, S., Almeida, M., Silva-Ramos, M., Dias, L., Martins, S. and Castro Henriques, A. (2020). Lower donated kidney volume is associated with increased risk of lower graft function and acute rejection at 1 year after living donor kidney-a retrospective study. Transpl Int, 33 (12): 1711-1722. https://doi.org/10.1111/tri.13740
Silva, I., Magalhaes-Cardoso, M. T., Ferreirinha, F., Moreira, S., Costa, A. F., Silva, D., Vieira, C., Silva-Ramos, M. and Correia-de-Sa, P. (2020). beta3 Adrenoceptor-induced cholinergic inhibition in human and rat urinary bladders involves the exchange protein directly activated by cyclic AMP 1 favoring adenosine release. Br J Pharmacol, 177 (7): 1589-1608. https://doi.org/10.1111/bph.14921
Silva, T. B., Borges, F., Serrao, M. P. and Soares-da-Silva, P. (2020). Liver says no: the ongoing search for safe catechol O-methyltransferase inhibitors to replace tolcapone. Drug Discov Today, 25 (10): 1846-54. https://doi.org/10.1016/j.drudis.2020.07.015
Silva-Ramos, M., Silva, I., Faria, M., Ferreirinha, F. and Correia-de-Sa, P. (2020). Activation of Prejunctional P2x2/3 Heterotrimers by ATP Enhances the Cholinergic Tone in Obstructed Human Urinary Bladders. J Pharmacol Exp Ther, 372 (1): 63-72. https://doi.org/10.1124/jpet.119.261610
Teixeira-Santos, L., Albino-Teixeira, A. and Pinho, D. (2020). Neuroinflammation, oxidative stress and their interplay in neuropathic pain: Focus on specialized pro-resolving mediators and NADPH oxidase inhibitors as potential therapeutic strategies. Pharmacol Res, 162 105280. https://doi.org/10.1016/j.phrs.2020.105280
Torres-Costa, S., Penas, S., Carneiro, A., Santos-Silva, R., Moura, R., Brandao, E., Falcao-Reis, F. and Figueira, L. (2020). Idiopathic Acute Exudative Polymorphous Vitelliform Maculopathy: Insight into Imaging Features and Outcomes. Case Rep Ophthalmol Med, 2020 7254038. https://doi.org/10.1155/2020/7254038
Trinka, E., Rocamora, R., Chaves, J., Moreira, J., Ikedo, F., Soares-da-Silva, P. and Group, B.-E. I. S. (2020). Long-term efficacy and safety of eslicarbazepine acetate monotherapy for adults with newly diagnosed focal epilepsy: An open-label extension study. Epilepsia, 61 (10): 2129-2141. https://doi.org/10.1111/epi.16666

2019 (articles in alphabetic order)

1. AFONSO, J., ROCHA, C., LAGO, P., ARROJA, B., VIEIRA, A. I., DIAS, C. C. and MAGRO, F., (2019). Accuracy of a new rapid test assay for monitoring adalimumab levels. Journal of Crohns & Colitis, 13 S144-S144. <Go to ISI>://WOS:000460544500236

2. ARAUJO, A. M., MACHADO, H. S., FALCAO, A. C. and SOARES-DA-SILVA, P., (2019). Bioelectrical impedance analysis of body composition for the anesthetic induction dose of propofol in older patients. BMC Anesthesiol, 19 (1), 180. https://www.ncbi.nlm.nih.gov/pubmed/31604419

3. BANTLEON, F., SCHNEIDER, M., RICKEN, B., VELAYUTHAM, S., TRAPANI, D., AFONSO, J., MAGRO, F. and ABEL, A., (2019). Quantum blue anti-infliximab: development and evaluation of a point of care rapid test for measuring anti-infliximab antibodies in human serum. Journal of Crohns & Colitis, 13 S194-S195. <Go to ISI>://WOS:000460544501053

4. BARONE, V., BERTOLDO, G., MAGRO, F., BROCCANELLO, C., PUGLISI, I., BAGLIERI, A., CAGNIN, M., CONCHERI, G., SQUARTINI, A., PIZZEGHELLO, D., NARDI, S. and STEVANATO, P., (2019). Molecular and Morphological Changes Induced by Leonardite-based Biostimulant in Beta vulgaris L. Plants (Basel), 8 (6), https://www.ncbi.nlm.nih.gov/pubmed/31216763

5. BRAGANCA, B., NOGUEIRA-MARQUES, S., FERREIRINHA, F., FONTES-SOUSA, A. P. and CORREIA-DE-SA, P., (2019). The Ionotropic P2X4 Receptor has Unique Properties in the Heart by Mediating the Negative Chronotropic Effect of ATP While Increasing the Ventricular Inotropy. Front Pharmacol, 10 1103. https://www.ncbi.nlm.nih.gov/pubmed/31611793

6. BURISCH, J., KATSANOS, K. H., CHRISTODOULOU, D. K., BARROS, L., MAGRO, F., PEDERSEN, N., KJELDSEN, J., VEGH, Z., LAKATOS, P. L., ERIKSSON, C., HALFVARSON, J., FUMERY, M., GOWER-ROUSSEAU, C., BRINAR, M., CUKOVIC-CAVKA, S., NIKULINA, I., BELOUSOVA, E., MYERS, S., SEBASTIAN, S., KIUDELIS, G., KUPCINSKAS, L., SCHWARTZ, D., ODES, S., KAIMAKLIOTIS, I. P., VALPIANI, D., D'INCA, R., SALUPERE, R., ZAMMIT, S. C., ELLUL, P., DURICOVA, D., BORTLIK, M., GOLDIS, A., KIEVIT, H. A. L., TOCA, A., TURCAN, S., MIDJORD, J., NIELSEN, K. R., ANDERSEN, K. W., ANDERSEN, V., MISRA, R., AREBI, N., OKSANEN, P., COLLIN, P., DE CASTRO, L., HERNANDEZ, V., LANGHOLZ, E., MUNKHOLM, P. and GRP, E.-I., (2019). Natural Disease Course of Ulcerative Colitis During the First Five Years of Follow-up in a European Population-based Inception Cohort-An Epi-IBD Study. Journal of Crohns & Colitis, 13 (2), 198-208. <Go to ISI>://WOS:000459356300008

7. BURISCH, J., VARDI, H., SCHWARTZ, D., KRZNARIC, Z., LAKATOS, P. L., FUMERY, M., KUPCINSKAS, L., MAGRO, F., BELOUSOVA, E., OKSANEN, P., AREBI, N., LANGHOLZ, E., TURCAN, S., D'INCA, R., HERNANDEZ, V., VALPIANI, D., VEGH, Z., GIANNOTTA, M., KATSANOS, K. H., DURICOVA, D., NIELSEN, K. R., KIEVIT, H. A. L., ELLUL, P., SALUPERE, R., GOLDIS, A., KAIMAKLIOTIS, I., PEDERSEN, N., ANDERSEN, V., HALFVARSON, J., SEBASTIAN, S., DAHLERUP, J. F., MUNKHOLM, P., ODES, S. and EPI-IBD, (2019). Cost analysis in a prospective European population-based inception cohort: is there a cost-saving effect of biological therapy? Journal of Crohns & Colitis, 13 S9-S10. <Go to ISI>://WOS:000460544500016

8. BURISCH, J., ZAMMIT, S. C., ELLUL, P., TURCAN, S., DURICOVA, D., BORTLIK, M., ANDERSEN, K. W., ANDERSEN, V., KAIMAKLIOTIS, I. P., FUMERY, M., GOWER-ROUSSEAU, C., GIRARDIN, G., VALPIANI, D., GOLDIS, A., BRINAR, M., CUKOVIC-CAVKA, S., OKSANEN, P., COLLIN, P., BARROS, L., MAGRO, F., MISRA, R., AREBI, N., ERIKSSON, C., HALFVARSON, J., KIEVIT, H. A. L., PEDERSEN, N., KJELDSEN, J., MYERS, S., SEBASTIAN, S., KATSANOS, K. H., CHRISTODOULOU, D. K., MIDJORD, J., NIELSEN, K. R., KIUDELIS, G., KUPCINSKAS, L., NIKULINA, I., BELOUSOVA, E., SCHWARTZ, D., ODES, S., SALUPERE, R., CARMONA, A., PINEDA, J. R., VEGH, Z., LAKATOS, P. L., LANGHOLZ, E., MUNKHOLM, P. and EPI, I. B. D. g., (2019). Disease course of inflammatory bowel disease unclassified in a European population-based inception cohort: An Epi-IBD study. J Gastroenterol Hepatol, 34 (6), 996-1003. https://www.ncbi.nlm.nih.gov/pubmed/30562421

9. CABRAL, L., AFREIXO, V., MEIRELES, R., VAZ, M., FRADE, J. G., CHAVES, C., CAETANO, M., ALMEIDA, L. and PAIVA, J. A., (2019). Evaluation of Procalcitonin Accuracy for the Distinction Between Gram-Negative and Gram-Positive Bacterial Sepsis in Burn Patients. J Burn Care Res, 40 (1), 112-119. https://www.ncbi.nlm.nih.gov/pubmed/30481299

10. CABREIRA, V., SOARES-DA-SILVA, P. and MASSANO, J., (2019). Contemporary Options for the Management of Motor Complications in Parkinson's Disease: Updated Clinical Review. Drugs, 79 (6), 593-608. https://www.ncbi.nlm.nih.gov/pubmed/30905034

11. CASTELLAO-SANTANA, L. M., YUMI ABIKO, P., AMBIEL, C. R., PEIXOTO, A. R., NORONHA-MATOS, J. B., CORREIA-DE-SA, P. and ALVES-DO-PRADO, W., (2019). Tetanic Facilitation of Neuromuscular Transmission by Adenosine A2A and Muscarinic M1 Receptors is Dependent on the Uptake of Choline via High-Affinity Transporters. Pharmacology, 103 (1-2), 38-49. https://www.ncbi.nlm.nih.gov/pubmed/30380560

12. DANESE, S., ALLEZ, M., VAN BODEGRAVEN, A. A., DOTAN, I., GISBERT, J. P., HART, A., LAKATOS, P. L., MAGRO, F., PEYRIN-BIROULET, L., SCHREIBER, S., TARABAR, D., VAVRICKA, S., HALFVARSON, J. and VERMEIRE, S., (2019). Unmet Medical Needs in Ulcerative Colitis: An Expert Group Consensus. Digestive Diseases, 37 (4), 266-283. <Go to ISI>://WOS:000464379500002

13. DIAS, C. C., SANTIAGO, M., CORREIA, L., PORTELA, F., MINISTRO, P., LAGO, P., TRINDADE, E., FREITAS, A., MAGRO, F. and GEDII, (2019). Hospitalization trends of the Inflammatory Bowel Disease landscape: A nationwide overview of 16 years. Dig Liver Dis, 51 (7), 952-960. https://www.ncbi.nlm.nih.gov/pubmed/30826276

14. DOMENECH, E., PANES, J., HINOJOSA, J., ANNESE, V., MAGRO, F., STURNIOLO, G. C., BOSSA, F., FERNANDEZ, F., GONZALEZ-CONDE, B., GARCIA-SANCHEZ, V., DIGNASS, A., HERRERA, J. M., CABRIADA, J. L., GUARDIOLA, J., VECCHI, M., PORTELA, F., GINARD, D. and ULCEROSA, A. S. G. b. t. G. E. d. T. e. E. d. C. y. C., (2019). Corrigendum: Addition of Granulocyte/Monocyte Apheresis to Oral Prednisone for Steroid-dependent Ulcerative Colitis: A Randomized Multicentre Clinical Trial. J Crohns Colitis, 13 (6), 814. https://www.ncbi.nlm.nih.gov/pubmed/30951596

15. FERREIRA, J. J., LEES, A., ROCHA, J. F., POEWE, W., RASCOL, O. and SOARES-DA-SILVA, P., (2019). Long-term efficacy of opicapone in fluctuating Parkinson's disease patients: a pooled analysis of data from two phase 3 clinical trials and their open-label extensions. Eur J Neurol, 26 (7), 953-960. https://www.ncbi.nlm.nih.gov/pubmed/30681754

16. FONTES-SOUSA, A. P., SILVESTRE-FERREIRA, A. C., CARRETON, E., ESTEVES-GUIMARAES, J., MAIA-ROCHA, C., OLIVEIRA, P., LOBO, L., MORCHON, R., ARAUJO, F., SIMON, F. and MONTOYA-ALONSO, J. A., (2019). Exposure of humans to the zoonotic nematode Dirofilaria immitis in Northern Portugal. Epidemiol Infect, 147 e282. https://www.ncbi.nlm.nih.gov/pubmed/31793429

17. HAJIZADEH, H. S., HEIDARI, B., BERTOLDO, G., DELLA LUCIA, M. C., MAGRO, F., BROCCANELLO, C., BAGLIERI, A., PUGLISI, I., SQUARTINI, A., CAMPAGNA, G., CONCHERI, G., NARDI, S. and STEVANATO, P., (2019). Expression Profiling of Candidate Genes in Sugar Beet Leaves Treated with Leonardite-Based Biostimulant. High Throughput, 8 (4), https://www.ncbi.nlm.nih.gov/pubmed/31614507

18. HERNANDEZ, V., MARTINEZ-CADILLA, J., LANGHOLZ, E., CHRISTODOULOU, D., TURCAN, S., VALPIANI, D., LAKATOS, P. L., VEGH, Z., GOLDIS, A., BELOUSOVA, E., LADEFOGED, K., KIUDELIS, G., MCNAMARA, D., SHONOVA, O., KRZNARIC, Z., MAGRO, F., BJORNSSON, E. S., ALMER, S., FUMERY, M., DURICOVA, D., KIEVIT, A., KAIMAKLIOTIS, I., ELLUL, P., NIEWIADOMSKI, O., GIANNOTTA, M., ODES, S., PEDERSEN, N., DAHLERUP, J. F., SALUPERE, R., D'INCA, R., HALFVARSON, J., OKSANEN, P., AREBI, N., NIELSEN, K. R., ANDERSEN, V., SHAJI, S., MUNKHOLM, P., BURISCH, J. and EPI-IBD-GRP, (2019). Medical treatment and surgery in patients with elderly-onset inflammatory bowel disease: 3-year follow-up of Epi-IBD 2010-2011 cohorts. Journal of Crohns & Colitis, 13 S510-S511. <Go to ISI>://WOS:000460544503024

19. IGREJA, B., PIRES, N. M., WRIGHT, L. C. and SOARES-DA-SILVA, P., (2019). Effects of zamicastat treatment in a genetic model of salt-sensitive hypertension and heart failure. Eur J Pharmacol, 842 125-132. https://www.ncbi.nlm.nih.gov/pubmed/30401628

20. IGREJA, B., PIRES, N., LOUREIRO, A., WRIGHT, L. and SOARES-DA-SILVA, P., (2019). Cardiometabolic and Inflammatory Benefits of Sympathetic Down-Regulation with Zamicastat in Aged Spontaneously Hypertensive Rats. ACS Pharmacol Transl Sci, 2 (5), 353-360. https://www.ncbi.nlm.nih.gov/pubmed/32259069

21. LEAL, J., TEIXEIRA-SANTOS, L., PINHO, D., AFONSO, J., CARVALHO, J., DE LOURDES BASTOS, M., ALBINO-TEIXEIRA, A., FRAGA, S. and SOUSA, T., (2019). l-proline supplementation improves nitric oxide bioavailability and counteracts the blood pressure rise induced by angiotensin II in rats. Nitric Oxide, 82 1-11. https://www.ncbi.nlm.nih.gov/pubmed/30423454

22. LEES, A., FERREIRA, J. J., ROCHA, J. F., RASCOL, O., POEWE, W., GAMA, H. and SOARES-DA-SILVA, P., (2019). Safety Profile of Opicapone in the Management of Parkinson's Disease. J Parkinsons Dis, 9 (4), 733-740. https://www.ncbi.nlm.nih.gov/pubmed/31498127

23. LOPES, S., COSTA-SILVA, M., MAGINA, S., SILVA, M., MAGRO, F., AZEVEDO, F. and LISBOA, C., (2019). Concurrent Lip Chancre and Maculopapular Syphilides in a Patient under Anti-TNFalpha Therapy. Skinmed, 17 (5), 343-345. https://www.ncbi.nlm.nih.gov/pubmed/31782712

24. LOPES, S., GOMES, N., TRINDADE, E., AZEVEDO, F. and MAGINA, S., (2019). Hidradenitis suppurativa in a prepubertal girl. Acta Dermatovenerol Alp Pannonica Adriat, 28 (3), 139-141. https://www.ncbi.nlm.nih.gov/pubmed/31545394

25. LOPES, S., VIDE, J., COSTA-SILVA, M., AZEVEDO, F. and MAGINA, S., (2019). Awareness, knowledge, and practice patterns of general practitioner residents and specialists toward hidradenitis suppurativa: a survey study. Acta Dermatovenerol Alp Pannonica Adriat, 28 (2), 61-63. https://www.ncbi.nlm.nih.gov/pubmed/31233168

26. MAGRO, F. and ESTEVINHO, M. M., (2019). Moving from efficacy to effectiveness: budesonide multimatrix in ulcerative colitis. United European Gastroenterol J, 7 (9), 1153-1155. https://www.ncbi.nlm.nih.gov/pubmed/31700627

27. MAGRO, F., (2019). Anti-TNF treatment failure: drug levels, immunogenicity, or both? Lancet Gastroenterology & Hepatology, 4 (5), 326-327. <Go to ISI>://WOS:000463786300003

28. MAGRO, F., COELHO, R. and PEIXOTO, A., (2019). Can We Extrapolate Data from One Immune-Mediated Inflammatory Disease to Another One? Current Medicinal Chemistry, 26 (2), 248-258. <Go to ISI>://WOS:000461143200002

29. MAGRO, F., DIAS, C. C., PORTELA, F., MIRANDA, M., FERNANDES, S., BERNARDO, S., MINISTRO, P., LAGO, P., ROSA, I., PITA, I., CORREIA, L., RODRIGUES, P. P. and GEDII, (2019). Development and Validation of Risk Matrices Concerning Ulcerative Colitis Outcomes-Bayesian Network Analysis. J Crohns Colitis, 13 (4), 401-409. https://www.ncbi.nlm.nih.gov/pubmed/30329032

30. MAGRO, F., LOPES, J., BORRALHO, P., LOPES, S., COELHO, R., COTTER, J., CASTRO, F. D., SOUSA, H. T., SALGADO, M., ANDRADE, P., VIEIRA, A. I., FIGUEIREDO, P., CALDEIRA, P., SOUSA, A., DUARTE, M. A., AVILA, F., SILVA, J., MOLEIRO, J., MENDES, S., GIESTAS, S., MINISTRO, P., SOUSA, P., GONCALVES, R., GONCALVES, B., OLIVEIRA, A., ROSA, I., RODRIGUES, M., CHAGAS, C., DIAS, C. C., AFONSO, J., GEBOES, K., CARNEIRO, F. and PORTUGUESE, I. B. D. S. G., (2019). Comparison of different histological indexes in the assessment of UC activity and their accuracy regarding endoscopic outcomes and faecal calprotectin levels. Gut, 68 (4), 594-603. https://www.ncbi.nlm.nih.gov/pubmed/29437913

31. MAGRO, F., LOPES, S., SILVA, M., COELHO, R., PORTELA, F., BRANQUINHO, D., CORREIA, L., FERNANDES, S., CRAVO, M., CALDEIRA, P., TAVARES DE SOUSA, H., PATITA, M., LAGO, P., RAMOS, J., AFONSO, J., REDONDO, I., MACHADO, P., PHILIP, G., LOPES, J. and CARNEIRO, F., (2019). Soluble human Suppression of Tumorigenicity 2 is associated with endoscopic activity in patients with moderate-to-severe ulcerative colitis treated with golimumab. Therap Adv Gastroenterol, 12 1756284819869141. https://www.ncbi.nlm.nih.gov/pubmed/31516554

32. MAGRO, F., LOPES, S., SILVA, M., COELHO, R., PORTELA, F., BRANQUINHO, D., CORREIA, L., FERNANDES, S., CRAVO, M., CALDEIRA, P., SOUSA, H. T., PATITA, M., LAGO, P., RAMOS, J., AFONSO, J., REDONDO, I., MACHADO, P., CORNILLIE, F., LOPES, J., CARNEIRO, F. and PORTUGUESE, I. B. D. G., (2019). Low Golimumab Trough Levels at Week 6 Are Associated With Poor Clinical, Endoscopic and Histological Outcomes in Ulcerative Colitis Patients: Pharmacokinetic and Pharmacodynamic Sub-analysis of the Evolution Study. J Crohns Colitis, 13 (11), 1387-1393. https://www.ncbi.nlm.nih.gov/pubmed/30989180

33. MAGRO, F., LOPES, S., SILVA, M., COELHO, R., PORTELA, F., BRANQUINHO, D., CORREIA, L., FERNANDES, S., CRAVO, M., CALDEIRA, P., SOUSA, H., PATITA, M., LAGO, P., RAMOS, J., AFONSO, J., REDONDO, I., MACHADO, P., PHILIP, G., LOPES, J. and CARNEIRO, F., (2019). Correlation between soluble suppression of tumorigenicity 2 (sST2) and endoscopic activity in patients with moderate to severe ulcerative colitis under golimumab treatment: results of the EVOLUTION study. Journal of Crohns & Colitis, 13 S363-S363. <Go to ISI>://WOS:000460544502059

34. MOCUMBI, A. O., STOTHARD, J. R., CORREIA-DE-SA, P. and YACOUB, M., (2019). Endomyocardial Fibrosis: an Update After 70 Years. Curr Cardiol Rep, 21 (11), 148. https://www.ncbi.nlm.nih.gov/pubmed/31758352

35. NORONHA-MATOS, J. B., CARDOSO, R., CALEJO, I., MAGALHÃES-CARDOSO, M. T., I., S., COSTA, M. A., FERREIRINHA, F., FREITAS, R., PELLETIER, J., SÉVIGNY, J. and CORREIA-DE-SÁ, P., (2019). NTPDase3 enzyme inhibition or gene silencing rescues the osteogenic potential of post-menopausal mesenchymal stem cells (MSCs) derived from bone marrow. Purinergic Signal, 14 (Suppl 1), S14-S15. https://link.springer.com/journal/11302/14/1/suppl

36. NUNES-CARNEIRO, D., MARQUES-PINTO, A., BRAGA, I., CABRAL, J. F., ALMEIDA, M., CAVADAS, V., DE ALMEIDA, R., CASTRO-HENRIQUES, A., FRAGA, A. and SILVA-RAMOS, M., (2019). Mini-incision Living Donor Nephrectomy and Trans-peritoneal Laparoscopic Nephrectomy: Will There Be a Place for New Evidence? Transplant Proc, 51 (5), 1555-1558. https://www.ncbi.nlm.nih.gov/pubmed/31155191

37. NUNES-CARNEIRO, D., MARQUES-PINTO, A., VEIGA, C., BRAGA, I., CABRAL, J. F., ALMEIDA, M., CAVADAS, V., CASTRO-HENRIQUES, A., ALMEIDA, R., FRAGA, A. and SILVA-RAMOS, M., (2019). Which One Is the Best for Living Donation: A Multiple-Artery Left Kidney Nephrectomy or a Right Kidney Nephrectomy? Transplant Proc, 51 (5), 1559-1562. https://www.ncbi.nlm.nih.gov/pubmed/31155192

38. PATINHA, D., CARVALHO, C., ABREU, C., CUNHA, O. M., MOTA, M. C., AFONSO, J., ALBINO-TEIXEIRA, A., DINIZ, C. and MORATO, M., (2019). Diabetes downregulates renal adenosine A2A receptors in an experimental model of hypertension. PLoS One, 14 (5), e0217552. https://www.ncbi.nlm.nih.gov/pubmed/31150459

39. PEREIRA-CASTRO, J., BRAS-SILVA, C. and FONTES-SOUSA, A. P., (2019). Novel insights into the role of urotensin II in cardiovascular disease. Drug Discov Today, 24 (11), 2170-2180. https://www.ncbi.nlm.nih.gov/pubmed/31430542

40. PINHEIRO, S. D., SERRAO, M. P., SILVA, T., BORGES, F. and SOARES-DA-SILVA, P., (2019). Pharmacodynamic evaluation of novel Catechol-O-methyltransferase inhibitors. Eur J Pharmacol, 847 53-60. https://www.ncbi.nlm.nih.gov/pubmed/30685433

41. PIRES, N. M., IGREJA, B., SERRAO, M. P., MATIAS, E. F., MOURA, E., ANTONIO, T., CAMPOS, F. L., BRION, L., BERTORELLO, A. and SOARES-DA-SILVA, P., (2019). Acute salt loading induces sympathetic nervous system overdrive in mice lacking salt-inducible kinase 1 (SIK1). Hypertens Res, 42 (8), 1114-1124. https://www.ncbi.nlm.nih.gov/pubmed/30894696

42. POUILLON, L., DANESE, S., HART, A., FIORINO, G., ARGOLLO, M., SELMI, C., CARLO-STELLA, C., LOEUILLE, D., COSTANZO, A., LOPEZ, A., VEGNI, E., RADICE, S., GILARDI, D., SOCHA, M., FAZIO, M., GONZALEZ-LORENZO, M., BONOVAS, S., MAGRO, F. and PEYRIN-BIROULET, L., (2019). Consensus report: clinical recommendations for the prevention and management of the nocebo effect in biosimilar-treated IBD patients. Aliment Pharmacol Ther, 49 (9), 1181-1187. https://www.ncbi.nlm.nih.gov/pubmed/30932219

43. REIS, A., SANTOS, M., FURTADO, I., CRUZ, C., SA-COUTO, P., QUEIROS, A., ALMEIDA, L. and ROCHA, N., (2019). Disability and its clinical correlates in pulmonary hypertension measured through the World Health Organization Disability Assessment Schedule 2.0: a prospective, observational study. J Bras Pneumol, 45 (4), e20170355. https://www.ncbi.nlm.nih.gov/pubmed/31166372

44. RICKEN, B., SCHNEIDER, M., BANTLEON, F., VELAYUTHAM, S., TRAPANI, D., AFONSO, J., MAGRO, F. and ABEL, A., (2019). Quantum blue anti-adalimumab: development and evaluation of a point of care rapid test for measuring anti-adalimumab antibodies in human serum. Journal of Crohns & Colitis, 13 S166-S166. <Go to ISI>://WOS:000460544501005

45. ROCHA, C., AFONSO, J., LAGO, P., ARROJA, B., VIEIRA, A. I., DIAS, C. C. and MAGRO, F., (2019). Accuracy of the new rapid test for monitoring adalimumab levels. Therap Adv Gastroenterol, 12 1756284819828238. https://www.ncbi.nlm.nih.gov/pubmed/30833984

46. RODRIGUES, A. V., ALMEIDA, F. J. and VIEIRA-COELHO, M. A., (2019). Dimethyltryptamine: Endogenous Role and Therapeutic Potential. J Psychoactive Drugs, 51 (4), 299-310. https://www.ncbi.nlm.nih.gov/pubmed/31018803

47. ROSEIRA, J., MAGRO, F., FERNANDES, S., SIMOES, C., PORTELA, F., ISABEL, V. A., PATITA, M., LEAL, C., LAGO, P., CALDEIRA, P., GAGO, T., CURRAIS, P., SAMPAIO, A., DIAS, C., DE SOUSA, H. T. and GEDII, (2019). Sexual quality of life in inflammatory bowel disease: a multi-centre, national-level study. Journal of Crohns & Colitis, 13 S491-S492. <Go to ISI>://WOS:000460544502296

48. SANTIAGO, M., MAGRO, F., CORREIA, L., PORTELA, F., MINISTRO, P., LAGO, P. and DIAS, C. C., (2019). What forecasting the prevalence of inflammatory bowel disease may tell us about its evolution on a national scale. Therap Adv Gastroenterol, 12 1756284819860044. https://www.ncbi.nlm.nih.gov/pubmed/31467592

49. SILVA, T., MOHAMED, T., SHAKERI, A., RAO, P. P. N., SOARES DA SILVA, P., REMIAO, F. and BORGES, F., (2019). Repurposing nitrocatechols: 5-Nitro-alpha-cyanocarboxamide derivatives of caffeic acid and caffeic acid phenethyl ester effectively inhibit aggregation of tau-derived hexapeptide AcPHF6. Eur J Med Chem, 167 146-152. https://www.ncbi.nlm.nih.gov/pubmed/30771602

2018 (articles in alphabetical order)

1. ABREU, C. M., SOARES-DOS-REIS, R., MELO, P. N., RELVAS, J. B., GUIMARAES, J., SA, M. J., CRUZ, A. P. & MENDES PINTO, I. (2018). Emerging Biosensing Technologies for Neuroinflammatory and Neurodegenerative Disease Diagnostics. Front Mol Neurosci, 11 164. https://www.ncbi.nlm.nih.gov/pubmed/29867354

2. ADLBRECHT, C., BLANCO-VEREA, A., BOUZAS-MOSQUERA, M. C., BRION, M., BURTSCHER, M., CARBONE, F., CHANG, T. T., CHARMANDARI, E., CHEN, J. W., CORREIA-COSTA, L., DULLAART, R. P. F., ELEFTHERIADES, M., FERNANDEZ-FERNANDEZ, B., GOLIASCH, G., GREMMEL, T., GROENEVELD, M. E., HENRIQUE, A., HUELSMANN, M., JUNG, C., LICHTENAUER, M., MONTECUCCO, F., NICOLAIDES, N. C., NIESSNER, A., PALMEIRA, C., PIRKLBAUER, M., SANCHEZ-NINO, M. D., SOTIRIADIS, A., SOUSA, T., SULZGRUBER, P., VAN BEEK, A. P., VERONESE, N., WINTER, M. P., YEUNG, K. K. & BOUZAS-MOSQUERA, A. (2018). Research update for articles published in EJCI in 2016. Eur J Clin Invest, 48 (10), e13016. https://www.ncbi.nlm.nih.gov/pubmed/30099749

3. ARAUJO, A. M., MACHADO, H. S., FALCAO, A. C. & SOARES-DA-SILVA, P. (2018). Reliability of body-weight scalars on the assessment of propofol induction dose in obese patients. Acta Anaesthesiol Scand, 62 (4), 464-473. https://www.ncbi.nlm.nih.gov/pubmed/29159892

4. ARMANDO, I., ASICO, L. D., WANG, X., JONES, J. E., SERRAO, M. P., CUEVAS, S., GRANDY, D. K., SOARES-DA-SILVA, P. & JOSE, P. A. (2018). Antihypertensive effect of etamicastat in dopamine D2 receptor-deficient mice. Hypertens Res, 41 (7), 489-498. https://www.ncbi.nlm.nih.gov/pubmed/29654295

5. BARROS-BARBOSA, A. R., OLIVEIRA, A., LOBO, M. G., CORDEIRO, J. M. & CORREIA-DE-SA, P. (2018). Under stressful conditions activation of the ionotropic P2X7 receptor differentially regulates GABA and glutamate release from nerve terminals of the rat cerebral cortex. Neurochem Int, 112 81-95. https://www.ncbi.nlm.nih.gov/pubmed/29154812

6. BECKONERT, N. M., OPITZ, T., PITSCH, J., SOARES DA SILVA, P. & BECK, H. (2018). Polyamine Modulation of Anticonvulsant Drug Response: A Potential Mechanism Contributing to Pharmacoresistance in Chronic Epilepsy. J Neurosci, 38 (24), 5596-5605. https://www.ncbi.nlm.nih.gov/pubmed/29789377

7. BESSA-GONCALVES, M., BRAGANCA, B., MARTINS-DIAS, E., CORREIA-DE-SA, P. & FONTES-SOUSA, A. P. (2018). Is the adenosine A2B 'biased' receptor a valuable target for the treatment of pulmonary arterial hypertension? Drug Discov Today, 23 (6), 1285-1292. https://www.ncbi.nlm.nih.gov/pubmed/29747005

8. BICKER, J., ALVES, G., FORTUNA, A., SOARES-DA-SILVA, P. & FALCAO, A. (2018). In vitro assessment of the interactions of dopamine beta-hydroxylase inhibitors with human P-glycoprotein and Breast Cancer Resistance Protein. Eur J Pharm Sci, 117 35-40. https://www.ncbi.nlm.nih.gov/pubmed/29428540

9. BURISCH, J., KIUDELIS, G., KUPCINSKAS, L., KIEVIT, H. A. L., ANDERSEN, K. W., ANDERSEN, V., SALUPERE, R., PEDERSEN, N., KJELDSEN, J., D'INCA, R., VALPIANI, D., SCHWARTZ, D., ODES, S., OLSEN, J., NIELSEN, K. R., VEGH, Z., LAKATOS, P. L., TOCA, A., TURCAN, S., KATSANOS, K. H., CHRISTODOULOU, D. K., FUMERY, M., GOWER-ROUSSEAU, C., ZAMMIT, S. C., ELLUL, P., ERIKSSON, C., HALFVARSON, J., MAGRO, F. J., DURICOVA, D., BORTLIK, M., FERNANDEZ, A., HERNANDEZ, V., MYERS, S., SEBASTIAN, S., OKSANEN, P., COLLIN, P., GOLDIS, A., MISRA, R., AREBI, N., KAIMAKLIOTIS, I. P., NIKUINA, I., BELOUSOVA, E., BRINAR, M., CUKOVIC-CAVKA, S., LANGHOLZ, E., MUNKHOLM, P. & EPI, I. B. D. G. (2018). Natural disease course of Crohn's disease during the first 5 years after diagnosis in a European population-based inception cohort: an Epi-IBD study. Gut, in press https://www.ncbi.nlm.nih.gov/pubmed/29363534

10. BURISCH, J., ZAMMIT, S. C., ELLUL, P., TURCAN, S., DURICOVA, D., BORTLIK, M., ANDERSEN, K. W., ANDERSEN, V., KAIMAKLIOTIS, I. P., FUMERY, M., GOWER-ROUSSEAU, C., GIRARDIN, G., VALPIANI, D., GOLDIS, A., BRINAR, M., CUKOVIC-CAVKA, S., OKSANEN, P., COLLIN, P., BARROS, L., MAGRO, F., MISRA, R., AREBI, N., ERIKSSON, C., HALFVARSON, J., KIEVIT, H. A. L., PEDERSEN, N., KJELDSEN, J., MYERS, S., SEBASTIAN, S., KATSANOS, K. H., CHRISTODOULOU, D. K., MIDJORD, J., NIELSEN, K. R., KIUDELIS, G., KUPCINSKAS, L., NIKULINA, I., BELOUSOVA, E., SCHWARTZ, D., ODES, S., SALUPERE, R., CARMONA, A., PINEDA, J. R., VEGH, Z., LAKATOS, P. L., LANGHOLZ, E., MUNKHOLM, P. & EPI, I. B. D. G. (2018). Disease course of inflammatory bowel disease unclassified in a European population-based inception cohort: An Epi-IBD study. J Gastroenterol Hepatol, in press https://www.ncbi.nlm.nih.gov/pubmed/30562421

11. CABRAL, L., AFREIXO, V., MEIRELES, R., VAZ, M., CHAVES, C., CAETANO, M., ALMEIDA, L. & PAIVA, J. A. (2018). Checking procalcitonin suitability for prognosis and antimicrobial therapy monitoring in burn patients. Burns Trauma, 6 10. https://www.ncbi.nlm.nih.gov/pubmed/29610766

12. CABRAL, L., AFREIXO, V., MEIRELES, R., VAZ, M., MARQUES, M., TOURAIS, I., CHAVES, C., ALMEIDA, L. & PAIVA, J. A. (2018). Procalcitonin kinetics after burn injury and burn surgery in septic and non-septic patients - a retrospective observational study. BMC Anesthesiol, 18 (1), 122. https://www.ncbi.nlm.nih.gov/pubmed/30185148

13. CHAPARRO, M., VERRETH, A., LOBATON, T., GRAVITO-SOARES, E., JULSGAARD, M., SAVARINO, E., MAGRO, F., AVNI BIRON, I., LOPEZ-SERRANO, P., CASANOVA, M. J., GOMPERTZ, M., VITOR, S., ARROYO, M., PUGLIESE, D., ZABANA, Y., VICENTE, R., AGUAS, M., BAR-GIL SHITRIT, A., GUTIERREZ, A., DOHERTY, G. A., FERNANDEZ-SALAZAR, L., MARTINEZ CADILLA, J., HUGUET, J. M., O'TOOLE, A., STASI, E., MANCENIDO MARCOS, N., VILLORIA, A., KARMIRIS, K., RAHIER, J. F., RODRIGUEZ, C., DIZ-LOIS PALOMARES, M., FIORINO, G., BENITEZ, J. M., PRINCIPI, M., NAFTALI, T., TAXONERA, C., MANTZARIS, G., SEBKOVA, L., IADE, B., LISSNER, D., FERRER BRADLEY, I., LOPEZ-SAN ROMAN, A., MARIN-JIMENEZ, I., MERINO, O., SIERRA, M., VAN DOMSELAAR, M., CAPRIOLI, F., GUERRA, I., PEIXE, P., PIQUERAS, M., RODRIGUEZ-LAGO, I., BER, Y., VAN HOEVE, K., TORRES, P., GRAVITO-SOARES, M., RUDBECK-RESDAL, D., BARTOLO, O., PEIXOTO, A., MARTIN, G., ARMUZZI, A., GARRE, A., DONDAY, M. G., MARTIN DE CARPI, F. J. & GISBERT, J. P. (2018). Long-Term Safety of In Utero Exposure to Anti-TNFalpha Drugs for the Treatment of Inflammatory Bowel Disease: Results from the Multicenter European TEDDY Study. Am J Gastroenterol, 113 (3), 396-403. https://www.ncbi.nlm.nih.gov/pubmed/29460920

14. CHARBIT-HENRION, F., PARLATO, M., HANEIN, S., DUCLAUX-LORAS, R., NOWAK, J., BEGUE, B., RAKOTOBE, S., BRUNEAU, J., FOURRAGE, C., ALIBEU, O., RIEUX-LAUCAT, F., LEVY, E., STOLZENBERG, M. C., MAZEROLLES, F., LATOUR, S., LENOIR, C., FISCHER, A., PICARD, C., ALOI, M., AMIL DIAS, J., BEN HARIZ, M., BOURRIER, A., BREUER, C., BRETON, A., BRONSKI, J., BUDERUS, S., CANANZI, M., COOPMAN, S., CREMILLEUX, C., DABADIE, A., DUMANT-FOREST, C., EGRITAS GURKAN, O., FABRE, A., FISCHER, A., GERMAN DIAZ, M., GONZALEZ-LAMA, Y., GOULET, O., GUARISO, G., GURCAN, N., HOMAN, M., HUGOT, J. P., JEZIORSKI, E., KARANIKA, E., LACHAUX, A., LEWINDON, P., LIMA, R., MAGRO, F., MAJOR, J., MALAMUT, G., MAS, E., MATTYUS, I., MEARIN, L. M., MELEK, J., NAVAS-LOPEZ, V. M., PAERREGAARD, A., PELATAN, C., PIGNEUR, B., PINTO PAIS, I., REBEUH, J., ROMANO, C., SIALA, N., STRISCIUGLIO, C., TEMPIA-CALIERA, M., TOUNIAN, P., TURNER, D., URBONAS, V., WILLOT, S., RUEMMELE, F. M. & CERF-BENSUSSAN, N. (2018). Diagnostic Yield of Next-Generation Sequencing in Very Early-Onset Inflammatory Bowel Diseases: A Multicenter Study. J Crohns Colitis, in press https://www.ncbi.nlm.nih.gov/pubmed/29788237

15. CHETCUTI ZAMMIT, S., ELLUL, P., GIRARDIN, G., VALPIANI, D., NIELSEN, K. R., OLSEN, J., GOLDIS, A., LAZAR, D., SHONOVA, O., NOVAKOVA, M., SEBASTIAN, S., WHITEHEAD, E., CARMONA, A., MARTINEZ-CADILLA, J., DAHLERUP, J. F., KIEVIT, A. L. H., THORSGAARD, N., KATSANOS, K. H., CHRISTODOULOU, D. K., MAGRO, F., SALUPERE, R., PEDERSEN, N., KJELDSEN, J., CARLSEN, K., IOANNIS, K., BERGEMALM, D., HALFVARSON, J., DURICOVA, D., BORTLIK, M., COLLIN, P., OKSANEN, P., KIUDELIS, G., KUPCINSKAS, L., KUDSK, K., ANDERSEN, V., O'MORAIN, C., BAILEY, Y., DORON, S., SHMUEL, O., ALMER, S., AREBI, N., MISRA, R., CUKOVIC-CAVKA, S., BRINAR, M., MUNKHOLM, P., VEGH, Z. & BURISCH, J. (2018). Vitamin D deficiency in a European inflammatory bowel disease inception cohort: an Epi-IBD study. Eur J Gastroenterol Hepatol, 30 (11), 1297-1303. https://www.ncbi.nlm.nih.gov/pubmed/30134383

16. COSTA, R., MAGALHAES, L. M., GRACA, J., VIEIRA, M., GAMA, H., MOREIRA, J., ROCHA, J. F. & SOARES-DA-SILVA, P. (2018). Eslicarbazepine acetate exposure in pregnant women with epilepsy. Seizure, 58 72-74. https://www.ncbi.nlm.nih.gov/pubmed/29674237

17. COSTA, R., STEINHOFF, B., GAMA, H., IKEDO, F., ROCHA, J. F. & SOARES-DA-SILVA, P. (2018). Safety, Tolerability and Efficacy of Eslicarbazepine Acetate as Adjunctive Therapy in Patients Aged >/= 65 Years with Focal Seizures. Drugs Aging, 35 (12), 1109-1117. https://www.ncbi.nlm.nih.gov/pubmed/30387043

18. COSTA-SILVA, M., VIDE, J., LOPES, S., AZEVEDO, F. & MAGINA, S. (2018). Psoriasis and comorbidities: general practitioners’ awareness. Acta Dermatovenerologica Alpina, Pannonica et Adriatica, 27 5-7.

19. DIAS, C. C., PORTELA, F., FERNANDES, S., MINISTRO, P., LAGO, P., ROSA, I., CORREIA, L., MAGRO, F. & ON BEHALF, G. (2018). The timing of early therapeutic strategies has a significant impact on Crohn's disease prognosis. Dig Liver Dis, 50 (5), 462-468. https://www.ncbi.nlm.nih.gov/pubmed/29456097

20. DOMENECH, E., PANES, J., HINOJOSA, J., ANNESE, V., MAGRO, F., STURNIOLO, G. C., BOSSA, F., FERNANDEZ, F., GONZALEZ-CONDE, B., GARCIA-SANCHEZ, V., DIGNASS, A., HERRERA, J. M., CABRIADA, J. L., GUARDIOLA, J., VECCHI, M., PORTELA, F., GINARD, D. & ULCEROSA, A. S. G. B. T. G. E. D. T. E. E. D. C. Y. C. (2018). Addition of Granulocyte/Monocyte Apheresis to Oral Prednisone for Steroid-dependent Ulcerative Colitis: A Randomized Multicentre Clinical Trial. J Crohns Colitis, 12 (6), 687-694. https://www.ncbi.nlm.nih.gov/pubmed/29490024

21. ESTEVINHO, M. M., AFONSO, J., ROSA, I., LAGO, P., TRINDADE, E., CORREIA, L., DIAS, C. C., MAGRO, F. & GEDII (2018). Placebo Effect on the Health-related Quality of Life of Inflammatory Bowel Disease Patients: A Systematic Review With Meta-analysis. J Crohns Colitis, 12 (10), 1232-1244. https://www.ncbi.nlm.nih.gov/pubmed/30010736

22. FERREIRA, J. J., LEES, A. J., POEWE, W., RASCOL, O., ROCHA, J. F., KELLER, B. & SOARES-DA-SILVA, P. (2018). Effectiveness of opicapone and switching from entacapone in fluctuating Parkinson disease. Neurology, 90 (21), e1849-e1857. https://www.ncbi.nlm.nih.gov/pubmed/29695590

23. FERREIRO-IGLESIAS, R. & MAGRO, F. (2018). Young GI angle: Tips and tricks for an academic career. United European Gastroenterol J, 6 (6), 952-954. https://www.ncbi.nlm.nih.gov/pubmed/30023074

24. FIGUEIRA, L., FERREIRA, C., JANEIRO, C., SERRAO, P., FALCAO-REIS, F. & MOURA, D. (2018). Concentration gradient of noradrenaline from the periphery to the centre of the cornea - A clue to its origin. Exp Eye Res, 168 107-114. https://www.ncbi.nlm.nih.gov/pubmed/29339089

25. FIGUEIRA, L., JANEIRO, C., FERREIRINHA, F., SERRAO, P., PERESTRELO, S., FALCAO-REIS, F., CORREIA-DE-SA, P. & MOURA, D. (2018). Regulation of corneal noradrenaline release and topography of sympathetic innervation: Functional implications for adrenergic mechanisms in the human cornea. Exp Eye Res, 174 121-132. https://www.ncbi.nlm.nih.gov/pubmed/29803557

26. FONSECA, D. J. & VAZ DA SILVA, M. J. (2018). Cardiac channelopathies: The role of sodium channel mutations. Rev Port Cardiol, 37 (2), 179-199. https://www.ncbi.nlm.nih.gov/pubmed/29525288

27. GIDAL, B. E., JACOBSON, M. P., BEN-MENACHEM, E., CARRENO, M., BLUM, D., SOARES-DA-SILVA, P., FALCAO, A., ROCHA, F., MOREIRA, J., GRINNELL, T., LUDWIG, E., FIEDLER-KELLY, J., PASSARELL, J. & SUNKARANENI, S. (2018). Exposure-safety and efficacy response relationships and population pharmacokinetics of eslicarbazepine acetate. Acta Neurol Scand, 138 (3), 203-211. https://www.ncbi.nlm.nih.gov/pubmed/29732549

28. GONCALVES, J., MAGRO, F., DANESE, S., LAKATOS, P. L. & BEN-HORIN, S. (2018). Editorial: antigenic response to CT-P13 and infliximab originator in IBD shows similar epitope recognition-evidence from basic science supports safe switching to biosimilars. Authors' reply. Aliment Pharmacol Ther, 48 (5), 575-576. https://www.ncbi.nlm.nih.gov/pubmed/30156326

29. GONCALVES, J., SANTOS, M., ACURCIO, R., IRIA, I., GOUVEIA, L., MATOS BRITO, P., CATARINA CUNHA-SANTOS, A., BARBAS, A., GALVAO, J., BARBOSA, I., AIRES DA SILVA, F., ALCOBIA, A., CAVACO, M., CARDOSO, M., DELGADO ALVES, J., CAREY, J. J., DORNER, T., EURICO FONSECA, J., PALMELA, C., TORRES, J., LIMA VIEIRA, C., TRABUCO, D., FIORINO, G., STRIK, A., YAVZORI, M., ROSA, I., CORREIA, L., MAGRO, F., D'HAENS, G., BEN-HORIN, S., LAKATOS, P. L. & DANESE, S. (2018). Antigenic response to CT-P13 and infliximab originator in inflammatory bowel disease patients shows similar epitope recognition. Aliment Pharmacol Ther, 48 (5), 507-522. https://www.ncbi.nlm.nih.gov/pubmed/29873091

30. HOLTKAMP, D., OPITZ, T., HEBEISEN, S., SOARES-DA-SILVA, P. & BECK, H. (2018). Effects of eslicarbazepine on slow inactivation processes of sodium channels in dentate gyrus granule cells. Epilepsia, 59 (8), 1492-1506. https://www.ncbi.nlm.nih.gov/pubmed/29953587

31. IGREJA, B., PIRES, N. M., WRIGHT, L. C. & SOARES-DA-SILVA, P. (2018). Effects of zamicastat treatment in a genetic model of salt-sensitive hypertension and heart failure. Eur J Pharmacol, 842 125-132. https://www.ncbi.nlm.nih.gov/pubmed/30401628

32. JOZWIAK, S., VEGGIOTTI, P., MOREIRA, J., GAMA, H., ROCHA, F. & SOARES-DA-SILVA, P. (2018). Effects of adjunctive eslicarbazepine acetate on neurocognitive functioning in children with refractory focal-onset seizures. Epilepsy Behav, 81 1-11. https://www.ncbi.nlm.nih.gov/pubmed/29454255

33. KISS, L. E., BELIAEV, A., FERREIRA, H. S., ROSA, C. P., BONIFACIO, M. J., LOUREIRO, A. I., PIRES, N. M., PALMA, P. N. & SOARES-DA-SILVA, P. (2018). Discovery of a Potent, Long-Acting, and CNS-Active Inhibitor (BIA 10-2474) of Fatty Acid Amide Hydrolase. ChemMedChem, 13 (20), 2177-2188. https://www.ncbi.nlm.nih.gov/pubmed/30113139

34. KITAJIMA, T., MIZOTE, S., BONIFACIO, M. J., UMEMURA, T., YONEDA, K., MOSER, P., SOARES-DA-SILVA, P. & TANAKA, M. (2018). Inhibition of catechol-O-methyltransferase in the cynomolgus monkey by opicapone after acute and repeated administration. Neuropharmacology, 143 282-288. https://www.ncbi.nlm.nih.gov/pubmed/30290160

35. KRAUSS, G., BITON, V., HARVEY, J. H., ELGER, C., TRINKA, E., SOARES DA SILVA, P., GAMA, H., CHENG, H., GRINNELL, T. & BLUM, D. (2018). Influence of titration schedule and maintenance dose on the tolerability of adjunctive eslicarbazepine acetate: An integrated analysis of three randomized placebo-controlled trials. Epilepsy Res, 139 1-8. https://www.ncbi.nlm.nih.gov/pubmed/29127848

36. LEAL, J., TEIXEIRA-SANTOS, L., PINHO, D., AFONSO, J., CARVALHO, J., DE LOURDES BASTOS, M., ALBINO-TEIXEIRA, A., FRAGA, S. & SOUSA, T. (2018). l-proline supplementation improves nitric oxide bioavailability and counteracts the blood pressure rise induced by angiotensin II in rats. Nitric Oxide, 82 1-11. https://www.ncbi.nlm.nih.gov/pubmed/30423454

37. LOPES, S., ANDRADE, P., AFONSO, J., CUNHA, R., RODRIGUES-PINTO, E., RAMOS, I., MACEDO, G. & MAGRO, F. (2018). Monitoring Crohn's disease activity: endoscopy, fecal markers and computed tomography enterography. Therap Adv Gastroenterol, 11 1756284818769075. https://www.ncbi.nlm.nih.gov/pubmed/29760785

38. LOPES, S., ANDRADE, P., CUNHA, R. & MAGRO, F. (2018). Transmural healing in Crohn's disease: Beyond mural findings. Dig Liver Dis, 50 (1), 103-104. https://www.ncbi.nlm.nih.gov/pubmed/29089271

39. MAGRO, F. & ANTONIO, T. (2018) Fibrosis in ulcerative colitis. In R. F. (eds) Fibrostenotic Inflammatory Bowel Disease, Springer, Cham, 10 147-57

40. MAGRO, F. & SOUSA, H. T. (2018). Editorial: ulcerative colitis submucosal fibrosis and inflammation: more than just strictures. Aliment Pharmacol Ther, 47 (7), 1033-1034. https://www.ncbi.nlm.nih.gov/pubmed/29512912

41. MAGRO, F., ROCHA, C., VIEIRA, A. I., SOUSA, H. T., ROSA, I., LOPES, S., CARVALHO, J., DIAS, C. C. & AFONSO, J. (2018). The performance of Remicade(R)-optimized quantification assays in the assessment of Flixabi(R) levels. Therap Adv Gastroenterol, 11 1756284818796956. https://www.ncbi.nlm.nih.gov/pubmed/30263065

42. MCNULTY, P., PILCHER, R., RAMESH, R., NECUINIATE, R., HUGHES, A., FAREWELL, D., HOLMANS, P., JONES, L. & NETWORK, R. I. O. T. E. H. S. D. (2018). Reduced Cancer Incidence in Huntington's Disease: Analysis in the Registry Study. J Huntingtons Dis, 7 (3), 209-222. https://www.ncbi.nlm.nih.gov/pubmed/30103338

43. MELO, F. J. & MAGINA, S. (2018). Clinical management of Anti-TNF-alpha-induced psoriasis or psoriasiform lesions in inflammatory bowel disease patients: a systematic review. Int J Dermatol, 57 (12), 1521-1532. https://www.ncbi.nlm.nih.gov/pubmed/30028008

44. MENDES, P., MARTINHO, R., LEITE, S., MAIA-MOCO, L., LEITE-MOREIRA, A. F., LOURENCO, A. P. & MOREIRA-RODRIGUES, M. (2018). Chronic exercise induces pathological left ventricular hypertrophy in adrenaline-deficient mice. Int J Cardiol, 253 113-119. https://www.ncbi.nlm.nih.gov/pubmed/29306449

45. MIEHLKE, S., ACOSTA, M. B., BOUMA, G., CARPIO, D., MAGRO, F., MOREELS, T. & PROBERT, C. (2018). Oral budesonide in gastrointestinal and liver disease: A practical guide for the clinician. J Gastroenterol Hepatol, https://www.ncbi.nlm.nih.gov/pubmed/29603368

46. OLIVEIRA, A., MARTINHO, R., SERRAO, P. & MOREIRA-RODRIGUES, M. (2018). Epinephrine Released During Traumatic Events May Strengthen Contextual Fear Memory Through Increased Hippocampus mRNA Expression of Nr4a Transcription Factors. Front Mol Neurosci, 11 334. https://www.ncbi.nlm.nih.gov/pubmed/30319349

47. PEYRIN-BIROULET, L., BAUMGART, D. C., ARMUZZI, A., GIONCHETTI, P., SEBASTIAN, S., DANESE, S., MAGRO, F., HIGGINS, S., YAWORKSY, A., BANDERAS, B. & KACHROO, S. (2018). Quality of Care in Ulcerative Colitis: A Modified Delphi Panel Approach. Dig Dis, 36 (5), 346-353. https://www.ncbi.nlm.nih.gov/pubmed/29969780

48. PITA, I. & MAGRO, F. (2018). Advanced imaging techniques for small bowel Crohn's disease: what does the future hold? Therap Adv Gastroenterol, 11 1756283X18757185. https://www.ncbi.nlm.nih.gov/pubmed/29467827

49. REIS, A., SANTOS, M., FURTADO, I., CRUZ, C., SA-COUTO, P., QUEIRÓS, A., ALMEIDA, L. & ROCHA, N. (2018). Disability and its clinical correlates in pulmonary hypertension measured through the World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0): a prospective, observational study. J Bras Pneumol., 44 (6), 1-10.

50. REIS, A., SANTOS, M., VICENTE, M., FURTADO, I., CRUZ, C., MELO, A., CARVALHO, L., GONÇALVES, F., SA-COUTO, P. & ALMEIDA, L. (2018). Health-Related Quality of Life in Pulmonary Hypertension and Its Clinical Correlates: A Cross-Sectional Study. BioMed Research International, Article ID 3924517 https://www.hindawi.com/journals/bmri/2018/3924517/

51. SOUSA, H. T., BRITO, J. & MAGRO, F. (2018). New cross-sectional imaging in IBD. Curr Opin Gastroenterol, 34 (4), 194-207. https://www.ncbi.nlm.nih.gov/pubmed/29846256

52. TRINKA, E., BEN-MENACHEM, E., KOWACS, P. A., ELGER, C., KELLER, B., LOFFLER, K., ROCHA, J. F. & SOARES-DA-SILVA, P. (2018). Efficacy and safety of eslicarbazepine acetate versus controlled-release carbamazepine monotherapy in newly diagnosed epilepsy: A phase III double-blind, randomized, parallel-group, multicenter study. Epilepsia, 59 (2), 479-491. https://www.ncbi.nlm.nih.gov/pubmed/29369348

53. TRINKA, E., ROCHA, J. F. & SOARES-DA-SILVA, P. (2018). Response: Comparing the dosages of lacosamide, eslicarbazepine acetate, and controlled-release carbamazepine in noninferiority epilepsy monotherapy trials: How much "fair" is "fair". Epilepsia, 59 (4), 900-901. https://www.ncbi.nlm.nih.gov/pubmed/29604066

54. VAZ, R. P., CARDOSO, A., SERRAO, P., PEREIRA, P. A. & MADEIRA, M. D. (2018). Chronic stress leads to long-lasting deficits in olfactory-guided behaviors, and to neuroplastic changes in the nucleus of the lateral olfactory tract. Horm Behav, 98 130-144. https://www.ncbi.nlm.nih.gov/pubmed/29277699

55. VIDE, J., OSORIO, F., COSTA-SILVA, M., LOPES, S., AZEVEDO, F., CAMILA DIAS, C., MAGINA, S. & MAGRO, F. (2018). Cutaneous Morbidity Among Inflammatory Bowel Disease Patients: A Cohort Study. J Crohns Colitis, 12 (4), 442-451. https://www.ncbi.nlm.nih.gov/pubmed/29300856

2017 (articles in alphabetical order)

1. ABREU, C., AFONSO, J., CAMILA DIAS, C., RUAS, R., SARMENTO, A. & MAGRO, F. (2017). Serial Tuberculosis Screening in Inflammatory Bowel Disease Patients Receiving Anti-TNFalpha Therapy. J Crohns Colitis, 11 (10), 1223-1229. https://www.ncbi.nlm.nih.gov/pubmed/28605520

2. ABREU, C., SARMENTO, A. & MAGRO, F. (2017). Screening, prophylaxis and counselling before the start of biological therapies: A practical approach focused on IBD patients. Dig Liver Dis, 49 (12), 1289-1297. https://www.ncbi.nlm.nih.gov/pubmed/28986117

3. AFONSO, J., DE SOUSA, H. T., ROSA, I., CARVALHO, J., DIAS, C. C. & MAGRO, F. (2017). Therapeutic drug monitoring of CT-P13: a comparison of four different immunoassays. Therap Adv Gastroenterol, 10 (9), 661-671. https://www.ncbi.nlm.nih.gov/pubmed/28932268

4. ARAUJO, A. M., MACHADO, H. S., FALCAO, A. C. & SOARES-DA-SILVA, P. (2017). Reliability of body-weight scalars on the assessment of propofol induction dose in obese patients. Acta Anaesthesiol Scand, in press https://www.ncbi.nlm.nih.gov/pubmed/29159892

5. BICKER, J., FORTUNA, A., ALVES, G., SOARES-DA-SILVA, P. & FALCAO, A. (2017). Elucidation of the Impact of P-glycoprotein and Breast Cancer Resistance Protein on the Brain Distribution of Catechol-O-Methyltransferase Inhibitors. Drug Metab Dispos, 45 (12), 1282-1291. https://www.ncbi.nlm.nih.gov/pubmed/28916530

6. BURISCH, J., VEGH, Z., KATSANOS, K. H., CHRISTODOULOU, D. K., LAZAR, D., GOLDIS, A., O'MORAIN, C., FERNANDEZ, A., PEREIRA, S., MYERS, S., SEBASTIAN, S., PEDERSEN, N., OLSE, J., RUBEK NIELSEN, K., SCHWARTZ, D., ODES, S., ALMER, S., HALFVARSON, J., TURK, N., CUKOVIC-CAVKA, S., NIKULINA, I., BELOUSOVA, E., DURICOVA, D., BORTLIK, M., SHONOVA, O., SALUPERE, R., BARROS, L., MAGRO, F., JONAITIS, L., KUPCINSKAS, L., TURCAN, S., KAIMAKLIOTIS, I., LADEFOGED, K., KUDSK, K., ANDERSEN, V., VIND, I., THORSGAARD, N., OKSANEN, P., COLLIN, P., DAL PIAZ, G., SANTINI, A., NIEWIADOMSKI, O., BELL, S., MOUM, B., AREBI, N., KJELDSEN, J., CARLSEN, K., LANGHOLZ, E., LAKATOS, P. L., MUNKHOLM, P., GERDES, L. U., DAHLERUP, J. F. & EPICOM STUDY, G. (2017). Occurrence of Anaemia in the First Year of Inflammatory Bowel Disease in a European Population-based Inception Cohort-An ECCO-EpiCom Study. J Crohns Colitis, 11 (10), 1213-1222. https://www.ncbi.nlm.nih.gov/pubmed/28575481

7. CAVALCANTE, W. L. G., NORONHA-MATOS, J. B., TIMOTEO, M. A., FONTES, M. R. M., GALLACCI, M. & CORREIA-DE-SA, P. (2017). Neuromuscular paralysis by the basic phospholipase A2 subunit of crotoxin from Crotalus durissus terrificus snake venom needs its acid chaperone to concurrently inhibit acetylcholine release and produce muscle blockage. Toxicol Appl Pharmacol, 334 8-17. https://www.ncbi.nlm.nih.gov/pubmed/28867438

8. CERTAL, M., VINHAS, A., BARROS-BARBOSA, A., FERREIRINHA, F., COSTA, M. A. & CORREIA-DE-SA, P. (2017). ADP-Induced Ca(2+) Signaling and Proliferation of Rat Ventricular Myofibroblasts Depend on Phospholipase C-Linked TRP Channels Activation Within Lipid Rafts. J Cell Physiol, 232 (6), 1511-1526. https://www.ncbi.nlm.nih.gov/pubmed/27755650

9. CORREIA-SA, I., SERRAO, P., MARQUES, M. & VIEIRA-COELHO, M. A. (2017). Hypertrophic Scars: Are Vitamins and Inflammatory Biomarkers Related with the Pathophysiology of Wound Healing? Obes Surg, 27 (12), 3170-3178. https://www.ncbi.nlm.nih.gov/pubmed/28569361

10.COSTA PEREIRA, C., DURAES, C., COELHO, R., GRACIO, D., SILVA, M., PEIXOTO, A., LAGO, P., PEREIRA, M., CATARINO, T., PINHO, S., TEIXEIRA, J. P., MACEDO, G., ANNESE, V. & MAGRO, F. (2017). Association between Polymorphisms in Antioxidant Genes and Inflammatory Bowel Disease. PLoS One, 12 (1), e0169102. http://www.ncbi.nlm.nih.gov/pubmed/28052094

11.COSTA, S., CORREIA-DE-SA, P., PORTO, M. J. & CAINE, L. (2017). The Use of Laser Microdissection in Forensic Sexual Assault Casework: Pros and Cons Compared to Standard Methods. J Forensic Sci, 62 (4), 998-1006. https://www.ncbi.nlm.nih.gov/pubmed/28133731

12.DE VARGAS, L. D. S., GONCALVES, R., LARA, M. V. S., COSTA-FERRO, Z. S. M., SALAMONI, S. D., DOMINGUES, M. F., PIOVESAN, A. R., DE ASSIS, D. R., VINADE, L., CORRADO, A. P., ALVES-DO-PRADO, W., CORREIA-DE-SA, P., DA COSTA, J. C., IZQUIERDO, I., DAL BELO, C. A. & MELLO-CARPES, P. B. (2017). Methylprednisolone as a memory enhancer in rats: Effects on aversive memory, long-term potentiation and calcium influx. Brain Res, 1670 44-51. https://www.ncbi.nlm.nih.gov/pubmed/28606783

13.DIAS, C. C., PEREIRA RODRIGUES, P., FERNANDES, S., PORTELA, F., MINISTRO, P., MARTINS, D., SOUSA, P., LAGO, P., ROSA, I., CORREIA, L., MOURA SANTOS, P. & MAGRO, F. (2017). The risk of disabling, surgery and reoperation in Crohn's disease - A decision tree-based approach to prognosis. PLoS One, 12 (2), e0172165. https://www.ncbi.nlm.nih.gov/pubmed/28225800

14.DIAS, C. C., RODRIGUES, P. P., COELHO, R., SANTOS, P. M., FERNANDES, S., LAGO, P., CAETANO, C., RODRIGUES, A., PORTELA, F., OLIVEIRA, A., MINISTRO, P., CANCELA, E., VIEIRA, A. I., BAROSA, R., COTTER, J., CARVALHO, P., CREMERS, I., TRABULO, D., CALDEIRA, P., ANTUNES, A., ROSA, I., MOLEIRO, J., PEIXE, P., HERCULANO, R., GONCALVES, R., GONCALVES, B., SOUSA, H. T., CONTENTE, L., MORNA, H., LOPES, S., MAGRO, F. & ON BEHALF, G. (2017). Erratum: Development and Validation of Risk Matrices for Crohn's Disease Outcomes in Patients Who Underwent Early Therapeutic Interventions. J Crohns Colitis, 11 (4), 515. https://www.ncbi.nlm.nih.gov/pubmed/27927719

15.DIAS, C. C., RODRIGUES, P. P., COELHO, R., SANTOS, P. M., FERNANDES, S., LAGO, P., CAETANO, C., RODRIGUES, A., PORTELA, F., OLIVEIRA, A., MINISTRO, P., CANCELA, E., VIEIRA, A. I., BAROSA, R., COTTER, J., CARVALHO, P., CREMERS, I., TRABULO, D., CALDEIRA, P., ANTUNES, A., ROSA, I., MOLEIRO, J., PEIXE, P., HERCULANO, R., GONCALVES, R., GONCALVES, B., SOUSA, H. T., CONTENTE, L., MORNA, H., LOPES, S., MAGRO, F. & ON BEHALF, G. (2017). Development and Validation of Risk Matrices for Crohn's Disease Outcomes in Patients Who Underwent Early Therapeutic Interventions. J Crohns Colitis, 11 (4), 445-453. https://www.ncbi.nlm.nih.gov/pubmed/27683799

16.ELGER, C., KOEPP, M., TRINKA, E., VILLANUEVA, V., CHAVES, J., BEN-MENACHEN, E., KOWACS, P. A., GIL-NAGEL, A., MOREIRA, J., GAMA, H., ROCHA, J. F. & SOARES-DA-SILVA, P. (2017). Pooled efficacy and safety of eslicarbazepine acetate as add-on treatment in patients with focal-onset seizures: Data from four double-blind placebo-controlled pivotal phase III clinical studies. CNS Neurosci Ther, 23 (12), 961-972. https://www.ncbi.nlm.nih.gov/pubmed/29030894

17.ESTEVINHO, M. M., AFONSO, J., ROSA, I., LAGO, P., TRINDADE, E., CORREIA, L., DIAS, C. C., MAGRO, F. & GEDII (2017). A Systematic Review and Meta-Analysis of 6-Thioguanine Nucleotide Levels and Clinical Remission in Inflammatory Bowel Disease. J Crohns Colitis, 11 (11), 1381-1392. https://www.ncbi.nlm.nih.gov/pubmed/28981590

18.FERREIRA DE OLIVEIRA, J. M. P., PACHECO, A. R., COUTINHO, L., OLIVEIRA, H., PINHO, S., ALMEIDA, L., FERNANDES, E. & SANTOS, C. (2017). Combination of etoposide and fisetin results in anti-cancer efficiency against osteosarcoma cell models. Arch Toxicol, in press https://www.ncbi.nlm.nih.gov/pubmed/29270805

19.GAMA, H., VIEIRA, M., COSTA, R., GRACA, J., MAGALHAES, L. M. & SOARES-DA-SILVA, P. (2017). Safety Profile of Eslicarbazepine Acetate as Add-On Therapy in Adults with Refractory Focal-Onset Seizures: From Clinical Studies to 6 Years of Post-Marketing Experience. Drug Saf, 40 (12), 1231-1240. https://www.ncbi.nlm.nih.gov/pubmed/28752473

20.GOMES, T., GUIMARÃES, J., LEÃO, M., MOURA, C., GARRETT, C., AZEVEDO, E., MASSANO, J., OLIVEIRA, J. P. & CASTRO, P. (2017). Investigation of Genetic Aetiology in Neurodegenerative Ataxias: Recommendations from the Group of Neurogenetics of Centro Hospitalar São João, Portugal. Acta Med Port, 30 (6), 502-12.

21.GONCALVES, D., ALVES, G., FORTUNA, A., BONIFACIO, M. J., SOARES-DA-SILVA, P. & FALCAO, A. (2017). A single- and multiple-dose study to investigate the pharmacokinetics and pharmacodynamics of opicapone, a novel COMT inhibitor, in rat. Neuropharmacology, 125 146-155. https://www.ncbi.nlm.nih.gov/pubmed/28734868

22.GONCALVES, D., ALVES, G., FORTUNA, A., SOARES-DA-SILVA, P. & FALCAO, A. (2017). Pharmacokinetics of opicapone, a third-generation COMT inhibitor, after single and multiple oral administration: A comparative study in the rat. Toxicol Appl Pharmacol, 323 9-15. https://www.ncbi.nlm.nih.gov/pubmed/28322896

23.IVERSEN, L., DAUDEN, E., SEGAERT, S., FREEMAN, K., MAGINA, S., RIGOPOULOS, D. & THACI, D. (2017). Reformulations of well-known active ingredients in the topical treatment of psoriasis vulgaris can improve clinical outcomes for patients. J Eur Acad Dermatol Venereol, 31 (8), 1271-1284. https://www.ncbi.nlm.nih.gov/pubmed/28419600

24.KOPYLOV, U., PAPAMICHAEL, K., KATSANOS, K., WATERMAN, M., BAR-GIL SHITRIT, A., BOYSEN, T., PORTELA, F., PEIXOTO, A., SZILAGYI, A., SILVA, M., MACONI, G., HAR-NOY, O., BOSSUYT, P., MANTZARIS, G., BARREIRO DE ACOSTA, M., CHAPARRO, M., CHRISTODOULOU, D. K., ELIAKIM, R., RAHIER, J. F., MAGRO, F., DROBNE, D., FERRANTE, M., SONNENBERG, E., SIEGMUND, B., MULS, V., THURM, T., YANAI, H., DOTAN, I., RAINE, T., LEVIN, A., ISRAELI, E., GHALIM, F., CARBONNEL, F., VERMEIRE, S., BEN-HORIN, S. & ROBLIN, X. (2017). Impact of Infliximab and Cyclosporine on the Risk of Colectomy in Hospitalized Patients with Ulcerative Colitis Complicated by Cytomegalovirus-A Multicenter Retrospective Study. Inflamm Bowel Dis, 23 (9), 1605-1613. https://www.ncbi.nlm.nih.gov/pubmed/28590343

25.KRAUSS, G., BITON, V., HARVEY, J. H., ELGER, C., TRINKA, E., SOARES DA SILVA, P., GAMA, H., CHENG, H., GRINNELL, T. & BLUM, D. (2017). Influence of titration schedule and maintenance dose on the tolerability of adjunctive eslicarbazepine acetate: An integrated analysis of three randomized placebo-controlled trials. Epilepsy Res, 139 1-8. https://www.ncbi.nlm.nih.gov/pubmed/29127848

26.LEES, A. J., FERREIRA, J., RASCOL, O., POEWE, W., ROCHA, J. F., MCCRORY, M., SOARES-DA-SILVA, P. & INVESTIGATORS, B.-S. (2017). Opicapone as Adjunct to Levodopa Therapy in Patients With Parkinson Disease and Motor Fluctuations: A Randomized Clinical Trial. JAMA Neurol, 74 (2), 197-206. https://www.ncbi.nlm.nih.gov/pubmed/28027332

27.LEES, A. J., ROCHA, J. F. & SOARES-DA-SILVA, P. (2017). Concerns Regarding Opicapone as Adjunct to Levodopa Therapy-Reply. JAMA Neurol, 74 (7), 873. https://www.ncbi.nlm.nih.gov/pubmed/28531266

28.LEMOS, V., DE OLIVEIRA, R. M., NAIA, L., SZEGO, E., RAMOS, E., PINHO, S., MAGRO, F., CAVADAS, C., REGO, A. C., COSTA, V., OUTEIRO, T. F. & GOMES, P. (2017). The NAD+-dependent deacetylase SIRT2 attenuates oxidative stress and mitochondrial dysfunction and improves insulin sensitivity in hepatocytes. Hum Mol Genet, 26 (21), 4105-4117. https://www.ncbi.nlm.nih.gov/pubmed/28973648

29.LOPES, S., ANDRADE, P., CONDE, S., LIBERAL, R., DIAS, C. C., FERNANDES, S., PINHEIRO, J., SIMOES, J. S., CARNEIRO, F., MAGRO, F. & MACEDO, G. (2017). Looking into Enteric Virome in Patients with IBD: Defining Guilty or Innocence? Inflamm Bowel Dis, 23 (8), 1278-1284. https://www.ncbi.nlm.nih.gov/pubmed/28617757

30.LOPES, S., ANDRADE, P., CUNHA, R. & MAGRO, F. (2017). Transmural healing in Crohn's disease: Beyond mural findings. Dig Liver Dis, https://www.ncbi.nlm.nih.gov/pubmed/29089271

31.LOPES, S., ANDRADE, P., RODRIGUES-PINTO, E., AFONSO, J., MACEDO, G. & MAGRO, F. (2017). Fecal marker levels as predictors of need for endoscopic balloon dilation in Crohn's disease patients with anastomotic strictures. World J Gastroenterol, 23 (35), 6482-6490. https://www.ncbi.nlm.nih.gov/pubmed/29085198

32.LOPES, S., RODRIGUES-PINTO, E., ANDRADE, P., AFONSO, J., BARON, T. H., MAGRO, F. & MACEDO, G. (2017). Endoscopic balloon dilation of Crohn's disease strictures-safety, efficacy and clinical impact. World J Gastroenterol, 23 (41), 7397-7406. https://www.ncbi.nlm.nih.gov/pubmed/29151693

33.MAGALHAES, D., SOARES-DA-SILVA, P. & MAGRO, F. (2017). The effect of PRR ligands on the membrane potential of intestinal epithelial cells. Pharmacol Rep, 69 (5), 978-984. https://www.ncbi.nlm.nih.gov/pubmed/28837901

34.MAGRO, F., AFONSO, J., LOPES, S., COELHO, R., GONCALVES, R., CALDEIRA, P., LAGO, P., DE SOUSA, H. T., RAMOS, J., GONCALVES, A. R., MINISTRO, P., ROSA, I., MEIRA, T., ANDRADE, P., SOARES, J. B., CARVALHO, D., SOUSA, P., VIEIRA, A. I., LOPES, J., DIAS, C. C., GEBOES, K. & CARNEIRO, F. (2017). Clinical performance of an infliximab rapid quantification assay. Therap Adv Gastroenterol, 10 (9), 651-660. https://www.ncbi.nlm.nih.gov/pubmed/28932267

35.MAGRO, F., AFONSO, J., LOPES, S., COELHO, R., GONCALVES, R., CALDEIRA, P., LAGO, P., DE SOUSA, H. T., RAMOS, J., GONCALVES, A. R., MINISTRO, P., ROSA, I., VIEIRA, A. I., ANDRADE, P., SOARES, J. B., CARVALHO, D., SOUSA, P., MEIRA, T., LOPES, J., MOLEIRO, J., DIAS, C. C., FALCAO, A., GEBOES, K., CARNEIRO, F. & PORTUGUESE, I. B. D. S. G. (2017). Calprotectin and the Magnitude of Antibodies to Infliximab in Clinically-stable Ulcerative Colitis Patients are More Relevant Than Infliximab Trough Levels and Pharmacokinetics for Therapeutic Escalation. EBioMedicine, 21 123-130. https://www.ncbi.nlm.nih.gov/pubmed/28629912

36.MAGRO, F., DIAS, C. C., COELHO, R., SANTOS, P. M., FERNANDES, S., CAETANO, C., RODRIGUES, A., PORTELA, F., OLIVEIRA, A., MINISTRO, P., CANCELA, E., VIEIRA, A. I., BAROSA, R., COTTER, J., CARVALHO, P., CREMERS, I., TRABULO, D., CALDEIRA, P., ANTUNES, A., ROSA, I., MOLEIRO, J., PEIXE, P., HERCULANO, R., GONCALVES, R., GONCALVES, B., TAVARES SOUSA, H., CONTENTE, L., MORNA, H. & LOPES, S. (2017). Impact of Early Surgery and Immunosuppression on Crohn's Disease Disabling Outcomes. Inflamm Bowel Dis, 23 (2), 289-297. https://www.ncbi.nlm.nih.gov/pubmed/28107278

37.MAGRO, F., GIONCHETTI, P., ELIAKIM, R., ARDIZZONE, S., ARMUZZI, A., BARREIRO-DE ACOSTA, M., BURISCH, J., GECSE, K. B., HART, A. L., HINDRYCKX, P., LANGNER, C., LIMDI, J. K., PELLINO, G., ZAGOROWICZ, E., RAINE, T., HARBORD, M., RIEDER, F., EUROPEAN, C. S. & COLITIS, O. (2017). Third European Evidence-based Consensus on Diagnosis and Management of Ulcerative Colitis. Part 1: Definitions, Diagnosis, Extra-intestinal Manifestations, Pregnancy, Cancer Surveillance, Surgery, and Ileo-anal Pouch Disorders. J Crohns Colitis, 11 (6), 649-670. https://www.ncbi.nlm.nih.gov/pubmed/28158501

38.MAGRO, F., LOPES, S., COELHO, R., COTTER, J., DIAS DE CASTRO, F., TAVARES DE SOUSA, H., SALGADO, M., ANDRADE, P., VIEIRA, A. I., FIGUEIREDO, P., CALDEIRA, P., SOUSA, A., DUARTE, M. A., AVILA, F., SILVA, J., MOLEIRO, J., MENDES, S., GIESTAS, S., MINISTRO, P., SOUSA, P., GONCALVES, R., GONCALVES, B., OLIVEIRA, A., CHAGAS, C., TORRES, J., DIAS, C. C., LOPES, J., BORRALHO, P., AFONSO, J., GEBOES, K., CARNEIRO, F. & PORTUGUESE, I. B. D. S. G. (2017). Accuracy of Faecal Calprotectin and Neutrophil Gelatinase B-associated Lipocalin in Evaluating Subclinical Inflammation in UlceRaTIVE Colitis-the ACERTIVE study. J Crohns Colitis, 11 (4), 435-444. https://www.ncbi.nlm.nih.gov/pubmed/27664275

39.MONTEIRO, A., MASSANO, J., LEAO, M., GARRETT, C. & GRUPO DE NEUROGENETICA DO CENTRO HOSPITALAR SAO, J. (2017). [Genetic Study of Primary Dystonias: Recommendations from the Centro Hospitalar Sao Joao Neurogenetics Group]. Acta Med Port, 30 (4), 340-346. https://www.ncbi.nlm.nih.gov/pubmed/28555563

40.MORATO, M., CORREIA-COSTA, L., SOUSA, T., COSME, D., SCHAEFER, F., AREIAS, J. C., GUERRA, A., AFONSO, A. C., BARROS, H., AZEVEDO, A. & ALBINO-TEIXEIRA, A. (2017). Longer duration of obesity is associated with a reduction in urinary angiotensinogen in prepubertal children. Pediatr Nephrol, 32 (8), 1411-1422. https://www.ncbi.nlm.nih.gov/pubmed/28337615

41.PEIXOTO, A., COELHO, R., MAIA, T., SARMENTO, A., MAGRO, F. & MACEDO, G. (2017). Chronic Granulomatous Disease Mimicking Colonic Crohn's Disease Successfully Treated with Infliximab. ACG Case Rep J, 4 e46. https://www.ncbi.nlm.nih.gov/pubmed/28377934

42.PORTELA, F., DIAS, C. C., CALDEIRA, P., CRAVO, M., DEUS, J., GONCALVES, R., LAGO, P., MORNA, H., PEIXE, P., RAMOS, J., SOUSA, H., TAVARES, L., VASCONCELOS, H., MAGRO, F. & MINISTRO, P. (2017). The who-when-why triangle of CAM use among Portuguese IBD patients. Dig Liver Dis, 49 (4), 388-396. https://www.ncbi.nlm.nih.gov/pubmed/28117198

43.ROCHA, J. F., SICARD, E., FAUCHOUX, N., FALCAO, A., SANTOS, A., LOUREIRO, A. I., PINTO, R., BONIFACIO, M. J., NUNES, T., ALMEIDA, L. & SOARES-DA-SILVA, P. (2017). Effect of opicapone multiple-dose regimens on levodopa pharmacokinetics. Br J Clin Pharmacol, 83 (3), 540-553. https://www.ncbi.nlm.nih.gov/pubmed/27763682

44.SILVA, I., COSTA, A. F., MOREIRA, S., FERREIRINHA, F., MAGALHAES-CARDOSO, M. T., CALEJO, I., SILVA-RAMOS, M. & CORREIA-DE-SA, P. (2017). Inhibition of cholinergic neurotransmission by beta3-adrenoceptors depends on adenosine release and A1-receptor activation in human and rat urinary bladders. Am J Physiol Renal Physiol, 313 (2), F388-F403. https://www.ncbi.nlm.nih.gov/pubmed/28446460

45.VIDE, J. & MAGINA, S. (2017). Moderate to severe psoriasis treatment challenges through the era of biological drugs. An Bras Dermatol, 92 (5), 668-674. https://www.ncbi.nlm.nih.gov/pubmed/29166504

46.VIDE, J., OSORIO, F., COSTA-SILVA, M., LOPES, S., AZEVEDO, F., DIAS, C. C., MAGINA, S. & MAGRO, F. (2017). Cutaneous morbidity among inflammatory bowel disease patients: a cohort study. J Crohns Colitis, in press https://www.ncbi.nlm.nih.gov/pubmed/29300856

47.VIEIRA, C., FERREIRINHA, F., MAGALHAES-CARDOSO, M. T., SILVA, I., MARQUES, P. & CORREIA-DE-SA, P. (2017). Post-inflammatory Ileitis Induces Non-neuronal Purinergic Signaling Adjustments of Cholinergic Neurotransmission in the Myenteric Plexus. Front Pharmacol, 8 811. https://www.ncbi.nlm.nih.gov/pubmed/29167643

48.VIEIRA-SOUSA, E., CAVALEIRO, J., MOURAO, A. F., RODRIGUES, A. M., ALBINO-TEIXEIRA, A., PIMENTEL-SANTOS, F. M., OLIVEIRA-RAMOS, F., CANHAO, H., POLIDO-PEREIRA, J., FONSECA, J. E., PEREIRA DA SILVA, J. A., ROMEU, J. C., MELO GOMES, J., COSTA, L., GRACA, L., LEANDRO, M. J., SANTOS, M. J., MACHADO, P. M. & RAMIRO, S. (2017). Acta Reumatologica Portuguesa: perspectives in 2017. Acta Reumatol Port, 42 (2), 110-111. https://www.ncbi.nlm.nih.gov/pubmed/28693032

2016 (articles in alphabetical order)

1. ABREU, C., ALMEIDA, F., FERRAZ, R., DIAS, C. C., SARMENTO, A. & MAGRO, F. (2016). The tuberculin skin test still matters for the screening of latent Tuberculosis infections among Inflammatory Bowel Disease patients. Dig Liver Dis, 48 (12), 1438-1443. https://www.ncbi.nlm.nih.gov/pubmed/27599804

2. ABREU, C., CARVALHO, T., SARMENTO, A. & MAGRO, F. (2016). Stool Isolation of Nocardia nova in Two Immunomodulated Patients With Inflammatory Bowel Diseases. J Clin Gastroenterol, 50 (1), 92. http://www.ncbi.nlm.nih.gov/pubmed/26325188

3. ABREU, C., SARMENTO, A. & MAGRO, F. (2016). Reintroduction of Anti-TNFalpha Therapy After (or even During) Anti-TNFalpha-associated Tuberculosis in Immune-mediated Diseases. J Crohns Colitis, 10 (1), 120-1. http://www.ncbi.nlm.nih.gov/pubmed/26417047

4. AFONSO, J., LOPES, S., GONCALVES, R., CALDEIRA, P., LAGO, P., TAVARES DE SOUSA, H., RAMOS, J., GONCALVES, A. R., MINISTRO, P., ROSA, I., VIEIRA, A. I., COELHO, R., TAVARES, P., SOARES, J., SOUSA, A. L., CARVALHO, D., SOUSA, P., DA SILVA, J. P., MEIRA, T., SILVA FERREIRA, F., DIAS, C. C., CHOWERS, Y., BEN-HORIN, S., MAGRO, F. & ON BEHALF PORTUGUESE, I. B. D. S. G. (2016). Detection of anti-infliximab antibodies is impacted by antibody titer, infliximab level and IgG4 antibodies: a systematic comparison of three different assays. Therap Adv Gastroenterol, 9 (6), 781-794. http://www.ncbi.nlm.nih.gov/pubmed/27803733

5. AFONSO, J., LOPES, S., GONCALVES, R., CALDEIRA, P., LAGO, P., TAVARES DE SOUSA, H., RAMOS, J., GONCALVES, A. R., MINISTRO, P., ROSA, I., VIEIRA, A. I., DIAS, C. C., MAGRO, F. & PORTUGUESE, I. B. D. S. G. (2016). Proactive therapeutic drug monitoring of infliximab: a comparative study of a new point-of-care quantitative test with two established ELISA assays. Aliment Pharmacol Ther, 44 (7), 684-92. http://www.ncbi.nlm.nih.gov/pubmed/27507790

6. AGRA, R. M., AL-DAGHRI, N. M., BADIMON, L., BODI, V., CARBONE, F., CHEN, M., CUBEDO, J., DULLAART, R. P., EIRAS, S., GARCIA-MONZON, C., GARY, T., GNONI, A., GONZALEZ-RODRIGUEZ, A., GREMMEL, T., HAFNER, F., HAKALA, T., HUANG, B., ICKMANS, K., IRACE, C., KHOLOVA, I., KIMER, N., KYTO, V., MARZ, W., MIAZGOWSKI, T., MOLLER, S., MONTECUCCO, F., NICCOLI, G., NIJS, J., OZBEN, S., OZBEN, T., PAPASSOTIRIOU, I., PAPASTAMATAKI, M., REINA-COUTO, M., RIOS-NAVARRO, C., RITSCH, A., SABICO, S., SEETHO, I. W., SEVERINO, A., SIPILA, J., SOUSA, T., TASZAREK, A., TAURINO, F., TIETGE, U. J., TRIPOLINO, C., VERLOOP, W., VOSKUIL, M. & WILDING, J. P. (2016). Research update for articles published in EJCI in 2014. Eur J Clin Invest, 46 (10), 880-94. http://www.ncbi.nlm.nih.gov/pubmed/27571922

7. ALMEIDA, J. C., WACHA, A., GOMES, P. S., ALVES, L. C., FERNANDES, M. H. V., SALVADO, I. M. M. & FERNANDES, M. H. R. (2016). A biocompatible hybrid material with simultaneous calcium and strontium release capability for bone tissue repair. Materials Science and Engineering C, 62 429-38.

8. ALMEIDA, J. C., WACHA, A., GOMES, P. S., FERNANDES, M. H. R., FERNANDES, M. H. V. & SALVADO, I. M. M. (2016). PDMS-SiO2-TiO2-CaO hybrid materials - Cytocompatibility and nanoscale surface features. Materials Science and Engineering C, 64 74-86. http://www.sciencedirect.com/science/article/pii/S0928493116302466

9. ALVES, E., LUKOYANOV, N., SERRAO, P., MOURA, D. & MOREIRA-RODRIGUES, M. (2016). Epinephrine increases contextual learning through activation of peripheral beta2-adrenoceptors. Psychopharmacology (Berl), 233 (11), 2099-108. http://www.ncbi.nlm.nih.gov/pubmed/26935825

10.AMORIM-BARBOSA, T., SERRAO, M. P., BRANDAO, I. & VIEIRA-COELHO, M. A. (2016). Catechol-O-methyltransferase activity in erythrocytes from patients with eating disorders. Eat Weight Disord, 21 (2), 221-7. http://www.ncbi.nlm.nih.gov/pubmed/26296436

11.ANDRADE, C., BEATO, J., MONTEIRO, A., COSTA, A., PENAS, S., GUIMARAES, J., REIS, F. F. & GARRETT, C. (2016). Reply to Letter: Spectral-domain optical coherence tomography as a potential biomarker in Huntington's disease. Mov Disord, 31 (11), 1762-1763. http://www.ncbi.nlm.nih.gov/pubmed/27548531

12.ANDRADE, C., BEATO, J., MONTEIRO, A., COSTA, A., PENAS, S., GUIMARAES, J., REIS, F. F. & GARRETT, C. (2016). Spectral-Domain Optical Coherence Tomography as a Potential Biomarker in Huntington's Disease. Mov Disord, 31 (3), 377-83. http://www.ncbi.nlm.nih.gov/pubmed/26853218

13.BARROS-BARBOSA, A. R., FERREIRINHA, F., OLIVEIRA, A., MENDES, M., LOBO, M. G., SANTOS, A., RANGEL, R., PELLETIER, J., SEVIGNY, J., CORDEIRO, J. M. & CORREIA-DE-SA, P. (2016). Adenosine A2A receptor and ecto-5'-nucleotidase/CD73 are upregulated in hippocampal astrocytes of human patients with mesial temporal lobe epilepsy (MTLE). Purinergic Signal, 12 (4), 719-734. https://www.ncbi.nlm.nih.gov/pubmed/27650530

14.BARROS-BARBOSA, A. R., FONSECA, A. L., GUERRA-GOMES, S., FERREIRINHA, F., SANTOS, A., RANGEL, R., LOBO, M. G., CORREIA-DE-SA, P. & CORDEIRO, J. M. (2016). Up-regulation of P2X7 receptor-mediated inhibition of GABA uptake by nerve terminals of the human epileptic neocortex. Epilepsia, 57 (1), 99-110. http://www.ncbi.nlm.nih.gov/pubmed/26714441

15.BELIAEV, A., FERREIRA, H. S., LEARMONTH, D. A., BONIFACIO, M. J., TORRAO, L., PIRES, N. M., SOARES-DA-SILVA, P. & KISS, L. E. (2016). Synthesis and structure-activity relationships of ionizable 1,3,4-oxadiazol-2(3H)-ones as peripherally selective FAAH inhibitors with improved aqueous solubility. Pure and Applied Chemistry, 88 (4), 341-347. <Go to ISI>://WOS:000377216400005

16.BICKER, J., ALVES, G., FORTUNA, A., SOARES-DA-SILVA, P. & FALCAO, A. (2016). A new PAMPA model using an in-house brain lipid extract for screening the blood-brain barrier permeability of drug candidates. Int J Pharm, 501 (1-2), 102-111. http://www.ncbi.nlm.nih.gov/pubmed/26836708

17.BRAGANCA, B., OLIVEIRA-MONTEIRO, N., FERREIRINHA, F., LIMA, P. A., FARIA, M., FONTES-SOUSA, A. P. & CORREIA-DE-SA, P. (2016). Ion Fluxes through KCa2 (SK) and Cav1 (L-type) Channels Contribute to Chronoselectivity of Adenosine A1 Receptor-Mediated Actions in Spontaneously Beating Rat Atria. Front Pharmacol, 7 45. http://www.ncbi.nlm.nih.gov/pubmed/27014060

18.CAMPOS, S., MONTEIRO, J., VALENZUELA, B., GONCALINHO, H., DE PINHO, P. G., FRESCO, P., FELIX, L. & ANTUNES, L. (2016). Evidence of Different Propofol Pharmacokinetics under Short and Prolonged Infusion Times in Rabbits. Basic Clin Pharmacol Toxicol, 118 (6), 421-31. http://www.ncbi.nlm.nih.gov/pubmed/26551921

19.CARNEIRO, L. S., FONSECA, A. M., SERRAO, P., MOTA, M. P., VASCONCELOS-RAPOSO, J. & VIEIRA-COELHO, M. A. (2016). Impact of physical exercise on catechol-O-methyltransferase activity in depressive patients: A preliminary communication. J Affect Disord, 193 117-122. http://www.ncbi.nlm.nih.gov/pubmed/26773917

20.CARNEIRO, L. S., MOTA, M. P., VIEIRA-COELHO, M. A., ALVES, R. C., FONSECA, A. M. & VASCONCELOS-RAPOSO, J. (2016). Monoamines and cortisol as potential mediators of the relationship between exercise and depressive symptoms. Eur Arch Psychiatry Clin Neurosci, in press http://www.ncbi.nlm.nih.gov/pubmed/27484978

21.CARNEIRO, L. S., MOTA, M. P., VIEIRA-COELHO, M. A., ROSENBAUM, S., FONSECA, A. M. & VASCONCELOS-RAPOSO, J. (2016). Exercise for adults with depressive symptoms: Beyond the weight loss paradigm. Psychiatry Res, 246 364-365. http://www.ncbi.nlm.nih.gov/pubmed/27776332

22.CARVALHO, A., PELAEZ-VARGAS, A., HANSFORD, D. J., FERNANDES, M. H. & MONTEIRO, F. J. (2016). Effects of Line and Pillar Array Microengineered SiO2 Thin Films on the Osteogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells. Langmuir, 32 (4), 1091-100. http://www.ncbi.nlm.nih.gov/pubmed/26771563

23.CÉSAR, A., CALISTRU, A., PARDAL, J., MAGINA, S., MOTA, A. & AZEVEDO, F. (2016). Cutaneous Richter Syndrome mimicking a lower limb cellulitis infection - a case report and review of the literature. Dermatology Online Journal, 22 (5), http://www.escholarship.org/uc/item/0r05j1cc

24.COELHO, R., MAGRO, F., SILVA, M. & MACEDO, G. (2016). Early surgery in Crohn's disease patients with entero-urinary fistulas: does it change the prognosis? Scand J Gastroenterol, 51 (6), 679-83. http://www.ncbi.nlm.nih.gov/pubmed/26679346

25.COELHO, R., PEIXOTO, A., AMIL-DIAS, J., TRINDADE, E., CAMPOS, M., MAGINA, S., CHARBIT-HENRION, F., LENOIR, C., LATOUR, S., MAGRO, F. & MACEDO, G. (2016). Refractory monogenic Crohn's disease due to X-linked inhibitor of apoptosis deficiency. Int J Colorectal Dis, 31 (6), 1235-6. http://www.ncbi.nlm.nih.gov/pubmed/26584814

26.COELHO, R., SILVA, M., GASPAR, R., SILVA, R., PAIVA, D., LOPES, J., LOPES, S., LOPES, J. M., MAGRO, F. & MACEDO, G. (2016). "A book should not be judged by its cover": two cases of intestinal adenocarcinoma as the first manifestation of Crohn's disease. Int J Colorectal Dis, 31 (5), 1061-2. http://www.ncbi.nlm.nih.gov/pubmed/26410262

27.CORREIA-COSTA, L., COSME, D., NOGUEIRA-SILVA, L., MORATO, M., SOUSA, T., MOURA, C., MOTA, C., GUERRA, A., ALBINO-TEIXEIRA, A., AREIAS, J. C., SCHAEFER, F., LOPES, C., AFONSO, A. C. & AZEVEDO, A. (2016). Gender and obesity modify the impact of salt intake on blood pressure in children. Pediatr Nephrol, 31 (2), 279-88. http://www.ncbi.nlm.nih.gov/pubmed/26420679

28.CORREIA-COSTA, L., MORATO, M., SOUSA, T., COSME, D., GUIMARAES, J. T., GUERRA, A., SCHAEFER, F., AFONSO, A. C., AZEVEDO, A. & ALBINO-TEIXEIRA, A. (2016). Urinary fibrogenic cytokines ET-1 and TGF-beta1 are associated with urinary angiotensinogen levels in obese children. Pediatr Nephrol, 31 (3), 455-64. http://www.ncbi.nlm.nih.gov/pubmed/26482255

29.CORREIA-COSTA, L., SOUSA, T., MORATO, M., COSME, D., AFONSO, J., AREIAS, J. C., SCHAEFER, F., GUERRA, A., AFONSO, A. C., AZEVEDO, A. & ALBINO-TEIXEIRA, A. (2016). Oxidative stress and nitric oxide are increased in obese children and correlate with cardiometabolic risk and renal function. Br J Nutr, 116 (5), 805-15. http://www.ncbi.nlm.nih.gov/pubmed/27480380

30.CORREIA-COSTA, L., SOUSA, T., MORATO, M., COSME, D., AFONSO, J., MOURA, C., MOTA, C., AREIAS, J. C., GUERRA, A., SCHAEFER, F., CALDAS AFONSO, A., BARROS, H., ALBINO-TEIXEIRA, A. & AZEVEDO, A. (2016). Association of myeloperoxidase levels with cardiometabolic factors and renal function in prepubertal children. Eur J Clin Invest, 46 (1), 50-9. http://www.ncbi.nlm.nih.gov/pubmed/26541603

31.COSTA, F., SOUSA GOMES, P. & FERNANDES, M. H. (2016). Osteogenic and Angiogenic Response to Calcium Silicate-based Endodontic Sealers. J Endod, 42 (1), 113-9. http://www.ncbi.nlm.nih.gov/pubmed/26577874

32.COSTA, S., REINA-COUTO, M., ALBINO-TEIXEIRA, A. & SOUSA, T. (2016). Statins and oxidative stress in chronic heart failure. Rev Port Cardiol, 35 (1), 41-57. http://www.ncbi.nlm.nih.gov/pubmed/26763895

33.COSTA-RODRIGUES, J., CARMO, S., PERPETUO, I. P., MONTEIRO, F. J. & FERNANDES, M. H. (2016). Osteoclastogenic differentiation of human precursor cells over micro- and nanostructured hydroxyapatite topography. Biochim Biophys Acta, 1860 (4), 825-35. http://www.ncbi.nlm.nih.gov/pubmed/26801877

34.COSTA-RODRIGUES, J., REIS, S., CASTRO, A. & FERNANDES, M. H. (2016). Bone Anabolic Effects of Soluble Si: In Vitro Studies with Human Mesenchymal Stem Cells and CD14+ Osteoclast Precursors. Stem Cells Int, 2016 5653275. http://www.ncbi.nlm.nih.gov/pubmed/26798359

35.DIAS SCHALCH, T., PORTA SANTOS FERNANDES, K., COSTA-RODRIGUES, J., PEREIRA GARCIA, M., AGNELLI MESQUITA-FERRARI, R., KALIL BUSSADORI, S. & FERNANDES, M. H. (2016). Photomodulation of the osteoclastogenic potential of oral squamous carcinoma cells. J Biophotonics, 9 (11-12), 1136-1147. https://www.ncbi.nlm.nih.gov/pubmed/27089455

36.FALCAO, A., ROCHA, J. F., SANTOS, A., NUNES, T. & SOARES-DA-SILVA, P. (2016). Opicapone pharmacokinetics and pharmacodynamics comparison between healthy Japanese and matched white subjects. Clin Pharmacol Drug Dev, 5 (2), 150-61. https://www.ncbi.nlm.nih.gov/pubmed/27138028

37.FERREIRA, J. J., LEES, A., ROCHA, J. F., POEWE, W., RASCOL, O. & SOARES-DA-SILVA, P. (2016). Opicapone as an adjunct to levodopa in patients with Parkinson’s disease and end-of-dose motor fluctuations: a randomised, double-blind, controlled trial. Lancet Neurol, 15 (2), 154-65. http://www.sciencedirect.com/science/article/pii/S1474442215003361

38.FIORINO, G., CORTES, P. N., ELLUL, P., FELICE, C., KARATZAS, P., SILVA, M., LAKATOS, P. L., BOSSA, F., UNGAR, B., SEBASTIAN, S., FURFARO, F., KARMIRIS, K., KATSANOS, K. H., MUSCAT, M., CHRISTODOULOU, D. K., MACONI, G., KOPYLOV, U., MAGRO, F., MANTZARIS, G. J., ARMUZZI, A., BOSCA-WATTS, M. M., BEN-HORIN, S., BONOVAS, S. & DANESE, S. (2016). Discontinuation of Infliximab in Patients With Ulcerative Colitis Is Associated With Increased Risk of Relapse: A Multinational Retrospective Cohort Study. Clin Gastroenterol Hepatol, 14 (10), 1426-1432 e1. http://www.ncbi.nlm.nih.gov/pubmed/27317850

39.GOMES, P. S., ZOMORODIAN, A., KWIATKOWSKI, L., LUTZE, R., BALKOWIEC, A., COLACO, B., PINHEIRO, V., FERNANDES, J. C., MONTEMOR, M. F. & FERNANDES, M. H. (2016). In vivo assessment of a new multifunctional coating architecture for improved Mg alloy biocompatibility. Biomed Mater, 11 (4), 045007. http://www.ncbi.nlm.nih.gov/pubmed/27508333

40.GONCALVES, E. M., OLIVEIRA, F. J., SILVA, R. F., NETO, M. A., FERNANDES, M. H., AMARAL, M., VALLET-REGI, M. & VILA, M. (2016). Three-dimensional printed PCL-hydroxyapatite scaffolds filled with CNTs for bone cell growth stimulation. J Biomed Mater Res B Appl Biomater, 104 (6), 1210-9. http://www.ncbi.nlm.nih.gov/pubmed/26089195

41.IGREJA, B., WRIGHT, L. C. & SOARES-DA-SILVA, P. (2016). Sustained high blood pressure reduction with etamicastat, a peripheral selective dopamine beta-hydroxylase inhibitor. J Am Soc Hypertens, 10 (3), 207-16. http://www.ncbi.nlm.nih.gov/pubmed/26803288

42.LEITAO, A. F., FARIA, M. A., FAUSTINO, A. M., MOREIRA, R., MELA, P., LOUREIRO, L., SILVA, I. & GAMA, M. (2016). A Novel Small-Caliber Bacterial Cellulose Vascular Prosthesis: Production, Characterization, and Preliminary In Vivo Testing. Macromol Biosci, 16 (1), 139-50. http://www.ncbi.nlm.nih.gov/pubmed/26388180

43.LOPES, S., ANDRADE, P., AFONSO, J., RODRIGUES-PINTO, E., DIAS, C. C., MACEDO, G. & MAGRO, F. (2016). Correlation Between Calprotectin and Modified Rutgeerts Score. Inflamm Bowel Dis, 22 (9), 2173-81. http://www.ncbi.nlm.nih.gov/pubmed/27482974

44.MAGALHAES, D., CABRAL, J. M., SOARES-DA-SILVA, P. & MAGRO, F. (2016). Role of epithelial ion transports in inflammatory bowel disease. Am J Physiol Gastrointest Liver Physiol, 310 (7), G460-76. http://www.ncbi.nlm.nih.gov/pubmed/26744474

45.MAGRO, F., COELHO, R., GUIMARAES, L. S., SILVA, M., PEIXOTO, A., LOPES, S. & MACEDO, G. (2016). Anti-TNF therapy and radiation exposure in Crohn's disease: chicken or egg? Scand J Gastroenterol, 51 (4), 511-2. http://www.ncbi.nlm.nih.gov/pubmed/26523855

46.MAGRO, F., LOPES, S. I., LOPES, J., PORTELA, F., COTTER, J., LOPES, S., MOREIRA, M. J., LAGO, P., PEIXE, P., ALBUQUERQUE, A., RODRIGUES, S., SILVA, M. R., MONTEIRO, P., LOPES, C., MONTEIRO, L., MACEDO, G., VELOSO, L., CAMILA, C., AFONSO, J., GEBOES, K., CARNEIRO, F. & PORTUGUESE, I. B. D. G. (2016). Histological Outcomes and Predictive Value of Faecal Markers in Moderately to Severely Active Ulcerative Colitis Patients Receiving Infliximab. J Crohns Colitis, 10 (12), 1407-1416. https://www.ncbi.nlm.nih.gov/pubmed/27226417

47.MAGRO, F., RAMOS, J., CORREIA, L., LAGO, P., PEIXE, P., GONCALVES, A. R., RODRIGUES, A., VIEIRA, C., FERREIRA, D., PEREIRA SILVA, J., TULIO, M. A., SALGUEIRO, P. & FERNANDES, S. (2016). [Portuguese Consensus on the Diagnosis, Prevention and Treatment of Anaemia in Inflammatory Bowel Disease]. Acta Med Port, 29 (2), 144-56. http://www.ncbi.nlm.nih.gov/pubmed/27234956

48.MANE, N., VIAIS, R., MARTINEZ-CUTILLAS, M., GALLEGO, D., CORREIA-DE-SA, P. & JIMENEZ, M. (2016). Inverse gradient of nitrergic and purinergic inhibitory cotransmission in the mouse colon. Acta Physiol (Oxf), 216 (1), 120-31. http://www.ncbi.nlm.nih.gov/pubmed/26347033

49.MASSANO, J., LEAO, M., GARRETT, C. & GRUPO DE NEUROGENETICA DO CENTRO HOSPITALAR SAO, J. (2016). [Investigation of Genetic Etiology in Neurodegenerative Dementias: Recommendations from the Centro Hospitalar Sao Joao Neurogenetics Group]. Acta Med Port, 29 (10), 675-679. http://www.ncbi.nlm.nih.gov/pubmed/28103467

50.MEIRELES, M., MOURA, E., VIEIRA-COELHO, M. A., SANTOS-BUELGA, C., GONZALEZ-MANZANO, S., DUENAS, M., MATEUS, N., FARIA, A. & CALHAU, C. (2016). Flavonoids as dopaminergic neuromodulators. Mol Nutr Food Res, 60 (3), 495-501. http://www.ncbi.nlm.nih.gov/pubmed/26582321

51.MEURICE, E., BOUCHART, F., HORNEZ, J. C., LERICHE, A., HAUTCOEUR, D., LARDOT, V., CAMBIER, F., FERNANDES, M. H. & MONTEIRO, F. (2016). Osteoblastic cells colonization inside beta-TCP macroporous structures obtained by ice-templating. Journal of the European Ceramic Society, 36 (12), 2895-2901. <Go to ISI>://WOS:000378362800006

52.NORONHA-MATOS, J. B. & CORREIA-DE-SA, P. (2016). Mesenchymal Stem Cells Ageing: Targeting the "Purinome" to Promote Osteogenic Differentiation and Bone Repair. J Cell Physiol, 231 (9), 1852-61. http://www.ncbi.nlm.nih.gov/pubmed/26754327

53.PEDROSA, A. F., MAGINA, S., AZEVEDO, F. & LISBOA, C. (2016). Re-emergence of syphilis in the biological era. Int J Dermatol, 55 (12), e626-e628. https://www.ncbi.nlm.nih.gov/pubmed/27496611

54.PEREIRA, C., COELHO, R., GRACIO, D., DIAS, C., SILVA, M., PEIXOTO, A., LOPES, P., COSTA, C., TEIXEIRA, J. P., MACEDO, G. & MAGRO, F. (2016). DNA Damage and Oxidative DNA Damage in Inflammatory Bowel Disease. J Crohns Colitis, 10 (11), 1316-1323. http://www.ncbi.nlm.nih.gov/pubmed/27095753

55.PORTELA, F., LAGO, P., COTTER, J., GONCALVES, R., VASCONCELOS, H., MINISTRO, P., LOPES, S., EUSEBIO, M., MORNA, H., CRAVO, M., PEIXE, P., CREMMERS, I., SOUSA, H., DEUS, J., DUARTE, M., MAGRO, F., INVESTIGATORS, C. & GEDII (2016). Anaemia in Patients with Inflammatory Bowel Disease - A Nationwide Cross-Sectional Study. Digestion, 93 (3), 214-220. http://www.ncbi.nlm.nih.gov/pubmed/27022722

56.REBELO, T. S., NORONHA, J. P., GALESIO, M., SANTOS, H., DINIZ, M., SALES, M. G., FERNANDES, M. H. & COSTA-RODRIGUES, J. (2016). Testing the variability of PSA expression by different human prostate cancer cell lines by means of a new potentiometric device employing molecularly antibody assembled on graphene surface. Mater Sci Eng C Mater Biol Appl, 59 1069-78. http://www.ncbi.nlm.nih.gov/pubmed/26652466

57.RIEDER, F., LATELLA, G., MAGRO, F., YUKSEL, E. S., HIGGINS, P. D., DI SABATINO, A., DE BRUYN, J. R., RIMOLA, J., BRITO, J., BETTENWORTH, D., VAN ASSCHE, G., BEMELMAN, W., D'HOORE, A., PELLINO, G. & DIGNASS, A. U. (2016). European Crohn's and Colitis Organisation Topical Review on Prediction, Diagnosis and Management of Fibrostenosing Crohn's Disease. J Crohns Colitis, 10 (8), 873-85. http://www.ncbi.nlm.nih.gov/pubmed/26928961

58.ROCHA, J. F., FERREIRA, J. J., FALCAO, A., SANTOS, A., PINTO, R., NUNES, T., ALMEIDA, L. & SOARES-DA-SILVA, P. (2016). Effect of 3 Single-Dose Regimens of Opicapone on Levodopa Pharmacokinetics, Catechol-O-Methyltransferase Activity and Motor Response in Patients With Parkinson Disease. Clin Pharmacol Drug Dev, 5 (3), 232-40. https://www.ncbi.nlm.nih.gov/pubmed/27163503

59.SALGADO, C. L., GRENHO, L., FERNANDES, M. H., COLACO, B. J. & MONTEIRO, F. J. (2016). Biodegradation, biocompatibility, and osteoconduction evaluation of collagen-nanohydroxyapatite cryogels for bone tissue regeneration. J Biomed Mater Res A, 104 (1), 57-70. http://www.ncbi.nlm.nih.gov/pubmed/26179958

60.SILVA-FERREIRA, F., AFONSO, J., PINTO-LOPES, P. & MAGRO, F. (2016). A Systematic Review on Infliximab and Adalimumab Drug Monitoring: Levels, Clinical Outcomes and Assays. Inflamm Bowel Dis, 22 (9), 2289-301. http://www.ncbi.nlm.nih.gov/pubmed/27508512

61.SILVA-RAMOS, M., SILVA, I., OLIVEIRA, J. C. & CORREIA-DE-SA, P. (2016). Increased Urinary Adenosine Triphosphate in Patients With Bladder Outlet Obstruction Due to Benign Prostate Hyperplasia. Prostate, 76 (15), 1353-63. http://www.ncbi.nlm.nih.gov/pubmed/27418113

62.SOARES-DA-SILVA, P., CABRAL, J. M., MAGALHAES, D., FRAGA, S. & MAGRO, F. (2016). Amine neurotransmitters, inflammation and epithelial sodium transport. Exp Physiol, 101 (4), 459-64. https://www.ncbi.nlm.nih.gov/pubmed/26548358

63.TORRES, T., FERREIRA, A., FERREIRA, P., HENRIQUES, M., LEITE, L., MAGINA, S., MARQUES-PINTO, G., OLIVEIRA, H., SOUSA-BASTO, A., BELLO, R. T., VARELA, P., MASSA, A., SELORES, M. & FILIPE, P. (2016). Portuguese Position Paper on the Use of Biosimilars in

64.Psoriasis. Acta Medica Portuguesa, 29 (9), 574-7. http://dx.doi.org/10.20344/amp.8118

65.VALENTE, T. A., SILVA, D. M., GOMES, P. S., FERNANDES, M. H., SANTOS, J. D. & SENCADAS, V. (2016). Effect of Sterilization Methods on Electrospun Poly(lactic acid) (PLA) Fiber Alignment for Biomedical Applications. ACS Appl Mater Interfaces, 8 (5), 3241-9. http://www.ncbi.nlm.nih.gov/pubmed/26756809

66.VIDE, J., MOREIRA, C., CUNHA, A. P., BALDAIA, H., MAGINA, S. & AZEVEDO, F. (2016). Generalized bullous fixed drug eruption due to bromhexine. Dermatology Online Journal, 22 (7), http://escholarship.org/uc/item/7nt074w4#page-1

2015 (articles in alphabetical order)

1. ABREU, C., ROCHA-PEREIRA, N., SARMENTO, A. & MAGRO, F. (2015). Nocardia infections among immunomodulated inflammatory bowel disease patients: A review. World J Gastroenterol, 21 (21), 6491-6498. http://www.ncbi.nlm.nih.gov/pubmed/26074688

2. ABREU, C., SANTOS, L. & MAGRO, F. (2015). Varicella Complicated by Severe Pneumonia and Shock in an Immunosuppressed Crohn's Disease Patient Under Azathioprine and Anti-Tumour Necrosis Factor Alpha. J Crohns Colitis, 9 (12), 1176-8. http://www.ncbi.nlm.nih.gov/pubmed/26351378

3. AMORIM-BARBOSA, T., SERRAO, M. P., BRANDAO, I. & VIEIRA-COELHO, M. A. (2015). Catechol-O-methyltransferase activity in erythrocytes from patients with eating disorders. Eat Weight Disord, in press http://www.ncbi.nlm.nih.gov/pubmed/26296436

4. ANDRADE, C., BARROS, P., CAMACHO, O., GARRETT, C. & GUIMARAES, J. (2015). Radiation-induced neurotoxicity: clinical and radiological improvement after hyperbaric oxygen therapy. Neurol Sci, 36 (6), 1057-9. http://www.ncbi.nlm.nih.gov/pubmed/25630455

5. ANDRADE, C., FARIA, O. & GUIMARAES, J. (2015). [Bilateral Optic Disc Edema Secondary to Amiodarone: Manifestation of an Iatrogenic Optic Neuropathy]. Acta Med Port, 28 (2), 256-9. http://www.ncbi.nlm.nih.gov/pubmed/26061517

6. BARROS, J., GRENHO, L., FERNANDES, M. H., MANUEL, C. M., MELO, L. F., NUNES, O. C., MONTEIRO, F. J. & FERRAZ, M. P. (2015). Anti-sessile bacterial and cytocompatibility properties of CHX-loaded nanohydroxyapatite. Colloids Surf B Biointerfaces, 130 305-14. http://www.ncbi.nlm.nih.gov/pubmed/25936560

7. BARROS-BARBOSA, A. R., LOBO, M. G., FERREIRINHA, F., CORREIA-DE-SA, P. & CORDEIRO, J. M. (2015). P2X7 receptor activation downmodulates Na-dependent high-affinity GABA and glutamate transport into rat brain cortex synaptosomes. Neuroscience, 306 74-90. http://www.ncbi.nlm.nih.gov/pubmed/26299340

8. BERTORELLO, A. M., PIRES, N., IGREJA, B., PINHO, M. J., VORKAPIC, E., WAGSATER, D., WIKSTROM, J., BEHRENDT, M., HAMSTEN, A., ERIKSSON, P., SOARES-DA-SILVA, P. & BRION, L. (2015). Increased Arterial Blood Pressure and Vascular Remodeling in Mice Lacking Salt-Inducible Kinase 1 (SIK1). Circ Res, 116 (4), 642-52. http://www.ncbi.nlm.nih.gov/pubmed/25556206

9. BONIFACIO, M. J., SOUSA, F., NEVES, M., PALMA, N., IGREJA, B., PIRES, N. M., WRIGHT, L. C. & SOARES-DA-SILVA, P. (2015). Characterization of the interaction of the novel antihypertensive etamicastat with human dopamine-beta-hydroxylase: Comparison with nepicastat. Eur J Pharmacol, 751C 50-58. http://www.ncbi.nlm.nih.gov/pubmed/25641750

10. BONIFACIO, M. J., TORRAO, L., LOUREIRO, A. I., PALMA, P. N., WRIGHT, L. C. & SOARES-DA-SILVA, P. (2015). Pharmacological profile of opicapone, a third-generation nitrocatechol catechol-O-methyl transferase inhibitor, in the rat. Br J Pharmacol, 172 (7), 1739-52. http://www.ncbi.nlm.nih.gov/pubmed/25409768

11. BOOKER, S. A., PIRES, N., COBB, S., SOARES-DA-SILVA, P. & VIDA, I. (2015). Carbamazepine and oxcarbazepine, but not eslicarbazepine, enhance excitatory synaptic transmission onto hippocampal CA1 pyramidal cells through an antagonist action at adenosine A1 receptors. Neuropharmacology, 93C 103-115. http://www.ncbi.nlm.nih.gov/pubmed/25656478

12. BURISCH, J., VARDI, H., PEDERSEN, N., BRINAR, M., CUKOVIC-CAVKA, S., KAIMAKLIOTIS, I., DURICOVA, D., BORTLIK, M., SHONOVA, O., VIND, I., AVNSTROM, S., THORSGAARD, N., KRABBE, S., ANDERSEN, V., DAHLERUP, J. F., KJELDSEN, J., SALUPERE, R., OLSEN, J., NIELSEN, K. R., MANNINEN, P., COLLIN, P., KATSANOS, K. H., TSIANOS, E. V., LADEFOGED, K., LAKATOS, L., BAILEY, Y., O'MORAIN, C., SCHWARTZ, D., LUPINACCI, G., DE PADOVA, A., JONAITIS, L., KUPCINSKAS, L., TURCAN, S., BARROS, L., MAGRO, F., LAZAR, D., GOLDIS, A., NIKULINA, I., BELOUSOVA, E., FERNANDEZ, A., PINEDA, J. R., ALMER, S., HALFVARSON, J., TSAI, H. H., SEBASTIAN, S., FRIGER, M., GREENBERG, D., LAKATOS, P. L., LANGHOLZ, E., ODES, S., MUNKHOLM, P. & EPICOM, G. (2015). Costs and resource utilization for diagnosis and treatment during the initial year in a European inflammatory bowel disease inception cohort: an ECCO-EpiCom Study. Inflamm Bowel Dis, 21 (1), 121-31. http://www.ncbi.nlm.nih.gov/pubmed/25437816

13. CABRAL, J. M., GRACIO, D., SOARES-DA-SILVA, P. & MAGRO, F. (2015). Short- and long-term regulation of intestinal Na+/H+ exchange by Toll-like receptors TLR4 and TLR5. Am J Physiol Gastrointest Liver Physiol, 309 (8), G703-15. http://www.ncbi.nlm.nih.gov/pubmed/26294670

14. CALVO, A. M., SANTOS, G. M., DIONISIO, T. J., MARQUES, M. P., BROZOSKI, D. T., LANCHOTE, V. L., FERNANDES, M. H., FARIA, F. A. & SANTOS, C. F. (2015). Quantification of piroxicam and 5'-hydroxypiroxicam in human plasma and saliva using liquid chromatography-tandem mass spectrometry following oral administration. J Pharm Biomed Anal, 120 212-220. http://www.ncbi.nlm.nih.gov/pubmed/26760238

15. CARDOSO, A. M., SCHETINGER, M. R., CORREIA-DE-SA, P. & SEVIGNY, J. (2015). Impact of ectonucleotidases in autonomic nervous functions. Auton Neurosci, 191 25-38. http://www.ncbi.nlm.nih.gov/pubmed/26008223

16. CARNEIRO, L. S., FONSECA, A. M., VIEIRA-COELHO, M. A., MOTA, M. P. & VASCONCELOS-RAPOSO, J. (2015). Effects of structured exercise and pharmacotherapy vs. pharmacotherapy for adults with depressive symptoms: A randomized clinical trial. J Psychiatr Res, 71 48-55. http://www.ncbi.nlm.nih.gov/pubmed/26522871

17. CERTAL, M., VINHAS, A., PINHEIRO, A. R., FERREIRINHA, F., BARROS-BARBOSA, A. R., SILVA, I., COSTA, M. A. & CORREIA-DE-SA, P. (2015). Calcium signaling and the novel anti-proliferative effect of the UTP-sensitive P2Y receptor in rat cardiac myofibroblasts. Cell Calcium, 58 (5), 518-33. http://www.ncbi.nlm.nih.gov/pubmed/26324417

18. COELHO, R., MAGRO, F., SILVA, M. & MACEDO, G. (2015). Early surgery in Crohn's disease patients with entero-urinary fistulas: does it change the prognosis? Scand J Gastroenterol, in press http://www.ncbi.nlm.nih.gov/pubmed/26679346

19. COELHO, R., PEIXOTO, A., AMIL-DIAS, J., TRINDADE, E., CAMPOS, M., MAGINA, S., CHARBIT-HENRION, F., LENOIR, C., LATOUR, S., MAGRO, F. & MACEDO, G. (2015). Refractory monogenic Crohn's disease due to X-linked inhibitor of apoptosis deficiency. Int J Colorectal Dis, in press http://www.ncbi.nlm.nih.gov/pubmed/26584814

20. CORREIA-COSTA, L., MORATO, M., SOUSA, T., COSME, D., GUIMARAES, J. T., GUERRA, A., SCHAEFER, F., AFONSO, A. C., AZEVEDO, A. & ALBINO-TEIXEIRA, A. (2015). Urinary fibrogenic cytokines ET-1 and TGF-beta1 are associated with urinary angiotensinogen levels in obese children. Pediatr Nephrol, in press http://www.ncbi.nlm.nih.gov/pubmed/26482255

21. CORREIA-COSTA, L., SOUSA, T., MORATO, M., COSME, D., AFONSO, J., MOURA, C., MOTA, C., AREIAS, J. C., GUERRA, A., SCHAEFER, F., AFONSO, A. C., BARROS, H., ALBINO-TEIXEIRA, A. & AZEVEDO, A. (2015). Association of myeloperoxidase levels with cardiometabolic factors and renal function in prepubertal children. Eur J Clin Invest, in press http://www.ncbi.nlm.nih.gov/pubmed/26541603

22. COSTA, F., SOUSA GOMES, P. & FERNANDES, M. H. (2015). Osteogenic and Angiogenic Response to Calcium Silicate-based Endodontic Sealers. J Endod, 42 (1), 113-9. http://www.ncbi.nlm.nih.gov/pubmed/26577874

23. DIAS, C. C., RODRIGUES, P. P., DA COSTA-PEREIRA, A. & MAGRO, F. (2015). Clinical predictors of colectomy in patients with ulcerative colitis: systematic review and meta-analysis of cohort studies. J Crohns Colitis, 9 (2), 156-63. http://www.ncbi.nlm.nih.gov/pubmed/25518058

24. DIGNASS, A. U., GASCHE, C., BETTENWORTH, D., BIRGEGARD, G., DANESE, S., GISBERT, J. P., GOMOLLON, F., IQBAL, T., KATSANOS, K., KOUTROUBAKIS, I., MAGRO, F., SAVOYE, G., STEIN, J., VAVRICKA, S., EUROPEAN, C. S. & COLITIS, O. (2015). European consensus on the diagnosis and management of iron deficiency and anaemia in inflammatory bowel diseases. J Crohns Colitis, 9 (3), 211-22. http://www.ncbi.nlm.nih.gov/pubmed/25518052

25. DOESER, A., DICKHOF, G., REITZE, M., UEBACHS, M., SCHAUB, C., PIRES, N. M., BONIFACIO, M. J., SOARES-DA-SILVA, P. & BECK, H. (2015). Targeting pharmacoresistant epilepsy and epileptogenesis with a dual-purpose antiepileptic drug. Brain, 138 (Pt 2), 371-87. http://www.ncbi.nlm.nih.gov/pubmed/25472797

26. FALCÃO, A., ROCHA, J. F., SANTOS, A., NUNES, T. & SOARES-DA-SILVA, P. (2015). Opicapone Pharmacokinetics andPharmacodynamics ComparisonBetween Healthy Japanese andMatched White Subjects. Clinical Pharmacologyin Drug Development, in press http://onlinelibrary.wiley.com/doi/10.1002/cpdd.213/epdf

27. FERRAZ, R., COSTA-RODRIGUES, J., FERNANDES, M. H., SANTOS, M. M., MARRUCHO, I. M., REBELO, L. P., PRUDENCIO, C., NORONHA, J. P., PETROVSKI, Z. & BRANCO, L. C. (2015). Antitumor Activity of Ionic Liquids Based on Ampicillin. ChemMedChem, 10 (9), 1480-3. http://www.ncbi.nlm.nih.gov/pubmed/26190053

28. FERREIRA, J. J., ROCHA, J. F., FALCAO, A., SANTOS, A., PINTO, R., NUNES, T. & SOARES-DA-SILVA, P. (2015). Effect of opicapone on levodopa pharmacokinetics, catechol-O-methyltransferase activity and motor fluctuations in patients with Parkinson's disease. Eur J Neurol, 22 (5), 815-e56. http://www.ncbi.nlm.nih.gov/pubmed/25649051

29. GONCALVES, A. P., CORDEIRO, J. M., MONTEIRO, J., LUCCHI, C., CORREIA-DE-SA, P. & VIDEIRA, A. (2015). Involvement of mitochondrial proteins in calcium signaling and cell death induced by staurosporine in Neurospora crassa. Biochim Biophys Acta, 1847 (10), 1064-1074. http://www.ncbi.nlm.nih.gov/pubmed/26004627

30. GONCALVES, D., ALVES, G., FORTUNA, A., SOARES-DA-SILVA, P. & FALCAO, A. (2015). Development of a liquid chromatography assay for the determination of opicapone and BIA 9-1079 in rat matrices. Biomed Chromatogr, 30 (3), 312-22. http://www.ncbi.nlm.nih.gov/pubmed/26147707

31. GONCALVES, P., MAGRO, F. & MARTEL, F. (2015). Metabolic inflammation in inflammatory bowel disease: crosstalk between adipose tissue and bowel. Inflamm Bowel Dis, 21 (2), 453-67. http://www.ncbi.nlm.nih.gov/pubmed/25248003

32. HINDRYCKX, P., BAERT, F., HART, A., MAGRO, F., ARMUZZI, A., PEYRIN-BIROULET, L., CLINICAL TRIAL COMMITTEE CLINCOM OF THE EUROPEAN, C. S. & COLITIS, O. (2015). Clinical trials in ulcerative colitis: a historical perspective. J Crohns Colitis, 9 (7), 580-8. http://www.ncbi.nlm.nih.gov/pubmed/25913641

33. IGREJA, B., PIRES, N. M., BONIFACIO, M. J., LOUREIRO, A. I., FERNANDES-LOPES, C., WRIGHT, L. C. & SOARES-DA-SILVA, P. (2015). Blood pressure-decreasing effect of etamicastat alone and in combination with antihypertensive drugs in the spontaneously hypertensive rat. Hypertens Res, 38 (1), 30-8. http://www.ncbi.nlm.nih.gov/pubmed/25298210

34. IGREJA, B., WRIGHT, L. C. & SOARES-DA-SILVA, P. (2015). Sustained high blood pressure reduction with etamicastat, a peripheral selective dopamine beta-hydroxylase inhibitor. J Am Soc Hypertens, in press http://www.ncbi.nlm.nih.gov/pubmed/26803288

35. LAM, W. Y. & FRESCO, P. (2015). Medication Adherence Measures: An Overview. Biomed Res Int, 2015 217047. http://www.ncbi.nlm.nih.gov/pubmed/26539470

36. LEAO, M., SOARES, J., GOMES, S., RAIMUNDO, L., RAMOS, H., BESSA, C., QUEIROZ, G., DOMINGOS, S., PINTO, M., INGA, A., CIDADE, H. & SARAIVA, L. (2015). Enhanced cytotoxicity of prenylated chalcone against tumour cells via disruption of the p53-MDM2 interaction. Life Sci, 142 60-65. http://www.ncbi.nlm.nih.gov/pubmed/26475964

37. LOUREIRO, A. I., BONIFACIO, M. J., FERNANDES-LOPES, C., PIRES, N., IGREJA, B., WRIGHT, L. C. & SOARES-DA-SILVA, P. (2015). Role of P-glycoprotein and permeability upon the brain distribution and pharmacodynamics of etamicastat: a comparison with nepicastat. Xenobiotica, 45 (9), 828-39. http://www.ncbi.nlm.nih.gov/pubmed/25915108

38. LOUREIRO, A. I. & SOARES-DA-SILVA, P. (2015). Distribution and pharmacokinetics of etamicastat and its N-acetylated metabolite (BIA 5-961) in dog and monkey. Xenobiotica, 45 (10), 903-11. http://www.ncbi.nlm.nih.gov/pubmed/25869244

39. MACONI, G. & MAGRO, F. (2015). Comparing techniques to achieve high accuracy and low cost: how should we first diagnose Crohn's disease? J Comp Eff Res, 4 (2), 75-8. http://www.ncbi.nlm.nih.gov/pubmed/25825838

40. MAGRO, F., COELHO, R., GUIMARAES, L. S., SILVA, M., PEIXOTO, A., LOPES, S. & MACEDO, G. (2015). Ionizing radiation exposure is still increasing in Crohn's disease: Who should be blamed? Scand J Gastroenterol, 50 (10), 1214-25. http://www.ncbi.nlm.nih.gov/pubmed/25881793

41. MAGRO, F., COELHO, R., GUIMARAES, L. S., SILVA, M., PEIXOTO, A., LOPES, S. & MACEDO, G. (2015). Anti-TNF therapy and radiation exposure in Crohn's disease: chicken or egg? Scand J Gastroenterol, 51 (4), 511-2. http://www.ncbi.nlm.nih.gov/pubmed/26523855

42. MAGRO, F., RODRIGUES-PINTO, E., COELHO, R., ANDRADE, P., SANTOS-ANTUNES, J., LOPES, S., CAMILA-DIAS, C. & MACEDO, G. (2015). Response to Targownik. Am J Gastroenterol, 110 (2), 349-51. http://www.ncbi.nlm.nih.gov/pubmed/25646916

43. MAGRO, F., RODRIGUES-PINTO, E., COELHO, R., ANDRADE, P., SANTOS-ANTUNES, J., LOPES, S., CAMILA-DIAS, C. & MACEDO, G. (2015). Response to Irwin et al. Am J Gastroenterol, 110 (6), 933-5. http://www.ncbi.nlm.nih.gov/pubmed/26052772

44. MARCOS, R., BRAGANCA, B. & FONTES-SOUSA, A. P. (2015). Image Analysis or Stereology: Which to Choose for Quantifying Fibrosis? J Histochem Cytochem, 63 (9), 734-6. http://www.ncbi.nlm.nih.gov/pubmed/26033333

45. MARQUES, C., AMORIM, M. M., PEREIRA, J. O., GUARDAO, L., MARTINS, M. J., PINTADO, M. E., MOURA, D., CALHAU, C. & PINHEIRO, H. (2015). In vitro ACE-inhibitory peptide KGYGGVSLPEW facilitates noradrenaline release from sympathetic nerve terminals: Relationship with the lack of antihypertensive effect on spontaneous hypertensive rats. Peptides, 71 72-76. http://www.ncbi.nlm.nih.gov/pubmed/26116781

46. MEIRELES, M., MOURA, E., VIEIRA-COELHO, M. A., SANTOS-BUELGA, C., GONZALEZ-MANZANO, S., DUENAS, M., MATEUS, N., FARIA, A. & CALHAU, C. (2015). Flavonoids as dopaminergic neuromodulators. Mol Nutr Food Res, in press http://www.ncbi.nlm.nih.gov/pubmed/26582321

47. MENDES, C. E., PALOMBIT, K., VIEIRA, C., SILVA, I., CORREIA-DE-SA, P. & CASTELUCCI, P. (2015). The Effect of Ischemia and Reperfusion on Enteric Glial Cells and Contractile Activity in the Ileum. Dig Dis Sci, 60 (9), 2677-89. http://www.ncbi.nlm.nih.gov/pubmed/25917048

48. MORAIS, D. S., COELHO, J., LOPES, M. A., FERRAZ, M. P., GOMES, P., FERNANDES, M. H., SANTOS, J. D. & SOORAJ HUSSAIN, N. (2015). Microanalysis of Bioactive Samarium Doped Glass-Reinforced Hydroxyapatite. Microsc Microanal, 21 ( Suppl 5), 31-2. http://www.ncbi.nlm.nih.gov/pubmed/26227696

49. NAZARETH, N., MAGRO, F., APPELBERG, R., SILVA, J., GRACIO, D., COELHO, R., CABRAL, J. M., ABREU, C., MACEDO, G., BULL, T. J. & SARMENTO, A. (2015). Increased viability but decreased culturability of Mycobacterium avium subsp. paratuberculosis in macrophages from inflammatory bowel disease patients under Infliximab treatment. Med Microbiol Immunol, 204 (6), 647-56. http://www.ncbi.nlm.nih.gov/pubmed/25702170

50. NAZARETH, N., MAGRO, F., MACHADO, E., RIBEIRO, T. G., MARTINHO, A., RODRIGUES, P., ALVES, R., MACEDO, G. N., GRACIO, D., COELHO, R., ABREU, C., APPELBERG, R., DIAS, C., MACEDO, G., BULL, T. & SARMENTO, A. (2015). Prevalence of Mycobacterium avium subsp. paratuberculosis and Escherichia coli in blood samples from patients with inflammatory bowel disease. Med Microbiol Immunol, 204 (6), 681-92. http://www.ncbi.nlm.nih.gov/pubmed/25994082

51. ORESLAND, T., BEMELMAN, W. A., SAMPIETRO, G. M., SPINELLI, A., WINDSOR, A., FERRANTE, M., MARTEAU, P., ZMORA, O., KOTZE, P. G., ESPIN-BASANY, E., TIRET, E., SICA, G., PANIS, Y., FAERDEN, A. E., BIANCONE, L., ANGRIMAN, I., SERCLOVA, Z., DE BUCK VAN OVERSTRAETEN, A., GIONCHETTI, P., STASSEN, L., WARUSAVITARNE, J., ADAMINA, M., DIGNASS, A., ELIAKIM, R., MAGRO, F., D'HOORE, A., EUROPEAN, C. S. & COLITIS, O. (2015). European evidence based consensus on surgery for ulcerative colitis. J Crohns Colitis, 9 (1), 4-25. http://www.ncbi.nlm.nih.gov/pubmed/25304060

52. PEREIRA, C., GRACIO, D., TEIXEIRA, J. P. & MAGRO, F. (2015). Oxidative Stress and DNA Damage: Implications in Inflammatory Bowel Disease. Inflamm Bowel Dis, 21 (10), 2403-17. http://www.ncbi.nlm.nih.gov/pubmed/26193347

53. PINTO, R., L’HOSTIS, P., PATAT, A., HOMERY, M. C., FALCÃO, A., NUNES, T., ROCHA, J. F. & SOARES-DA-SILVA, P. (2015). Evaluation of Opicapone on CardiacRepolarization in a ThoroughQT/QTc Study. Clinical Pharmacologyin Drug Development, 4 (6), 454-52. http://onlinelibrary.wiley.com/doi/10.1002/cpdd.188/abstract

54. PIRES, N., BONIFACIO, M. J. & SOARES-DA-SILVA, P. (2015). Carbamazepine aggravates absence seizures in two dedicated mouse models. Pharmacological Reports, 67 (5), 986-995. http://www.sciencedirect.com/science/article/pii/S1734114015000468

55. PIRES, N. M., IGREJA, B., MOURA, E., WRIGHT, L. C., SERRAO, M. P. & SOARES-DA-SILVA, P. (2015). Blood pressure decrease in spontaneously hypertensive rats folowing renal denervation or dopamine beta-hydroxylase inhibition with etamicastat. Hypertens Res, 38 (9), 605-12. http://www.ncbi.nlm.nih.gov/pubmed/25854989

56. PIRES, N. M., LOUREIRO, A. I., IGREJA, B., LACROIX, P. & SOARES-DA-SILVA, P. (2015). Cardiovascular safety pharmacology profile of etamicastat, a novel peripheral selective dopamine-ss-hydroxylase inhibitor. Eur J Pharmacol, 750C 98-107. http://www.ncbi.nlm.nih.gov/pubmed/25641747

57. QUELHAS-SANTOS, J., SAMPAIO-MAIA, B., REMIÃO, F., SERRÃO, P., SOARES-SILVA, I., DESIR, G. V. & PESTANA, M. (2015). Assessment of renalase activity on catecholamines degradation. Open Hypertension Journal, 7 (1), 14-18. http://benthamopen.com/ABSTRACT/TOHYPERJ-7-14

58. QUELHAS-SANTOS, J., SERRÃO, M. P., SOARES-SILVA, I., FERNANDES-CERQUEIRA, C., SIMÕES-SILVA, L., PINHO, M. J., REMIÃO, F., SAMPAIO-MAIA, B., DESIR, G. V. & PESTANA, M. (2015). Renalase regulates peripheral and central dopaminergic activities. American Journal of Physiology - Renal Physiology, 308 (2), F84-F91. http://www.scopus.com/inward/record.url?eid=2-s2.0-84920992145&partnerID=40&md5=c76d0c483befdec1a85a233ddc7f9c84

59. RIBEIRO, M., DE MORAES, M. A., BEPPU, M. M., GARCIA, M. P., FERNANDES, M. H., MONTEIRO, F. J. & FERRAZ, M. P. (2015). Development of silk fibroin/nanohydroxyapatite composite hydrogels for bone tissue engineering. European Polymer Journal, 67 (0), 66-77. http://www.sciencedirect.com/science/article/pii/S0014305715001913

60. ROCHA, J. F., FERREIRA, J. J., FALCÃO, A., SANTOS, A., PINTO, R., NUNES, T., ALMEIDA, L. & SOARES-DA-SILVA, P. (2015). Effect of 3 Single-Dose Regimens of Opicapone on Levodopa Pharmacokinetics, Catechol-O-Methyltransferase Activity and Motor Response in Patients With Parkinson Disease. Clinical Pharmacology in Drug Development, in press http://onlinelibrary.wiley.com/doi/10.1002/cpdd.217/epdf

61. RODRIGUES, S., LOPES, S., MAGRO, F., CARDOSO, H., HORTA, E. V. A. M., MARQUES, M., MARIZ, E., BERNARDES, M., LOPES, J., CARNEIRO, F. & MACEDO, G. (2015). Autoimmune hepatitis and anti-tumor necrosis factor alpha therapy: A single center report of 8 cases. World J Gastroenterol, 21 (24), 7584-8. http://www.ncbi.nlm.nih.gov/pubmed/26140007

62. RUNA, M. J., MATHEW, M. T., FERNANDES, M. H. & ROCHA, L. A. (2015). First insight on the impact of an osteoblastic layer on the bio-tribocorrosion performance of Ti6Al4V hip implants. Acta Biomater, 12 341-51. http://www.ncbi.nlm.nih.gov/pubmed/25448346

63. SILVA, C., RAMALHO, C., LUZ, I., MONTEIRO, J. & FRESCO, P. (2015). Drug-related problems in institutionalized, polymedicated elderly patients: opportunities for pharmacist intervention. Int J Clin Pharm, 37 (2), 327-34. http://www.ncbi.nlm.nih.gov/pubmed/25637404

64. SILVA, I., FERREIRINHA, F., MAGALHAES-CARDOSO, M. T., SILVA-RAMOS, M. & CORREIA-DE-SA, P. (2015). Activation of P2Y6 Receptors Facilitates Nonneuronal Adenosine Triphosphate and Acetylcholine Release from Urothelium with the Lamina Propria of Men with Bladder Outlet Obstruction. J Urol, 194 (4), 1146-54. http://www.ncbi.nlm.nih.gov/pubmed/26004864

65. SILVA, J. C., SAMPAIO, P., FERNANDES, M. H. & GOMES, P. S. (2015). The Osteogenic Priming of Mesenchymal Stem Cells is Impaired in Experimental Diabetes. J Cell Biochem, 116 (8), 1658-67. http://www.ncbi.nlm.nih.gov/pubmed/25704854

66. SILVA-RAMOS, M., SILVA, I., FARIA, M., MAGALHAES-CARDOSO, M. T., CORREIA, J., FERREIRINHA, F. & CORREIA-DE-SA, P. (2015). Impairment of ATP hydrolysis decreases adenosine A1 receptor tonus favoring cholinergic nerve hyperactivity in the obstructed human urinary bladder. Purinergic Signal, 11 (4), 595-606. http://www.ncbi.nlm.nih.gov/pubmed/26521170

67. SOARES, A. S., COSTA, V. M., DINIZ, C. & FRESCO, P. (2015). Inosine Strongly Enhances Proliferation of Human C32 Melanoma Cells through PLC-PKC-MEK1/2-ERK1/2 and PI3K Pathways. Basic Clin Pharmacol Toxicol, 116 (1), 25-36. http://www.ncbi.nlm.nih.gov/pubmed/24909096

68. SOARES, J. B., MARINHO, A. S., FERNANDES, D., MOREIRA GONCALVES, B., CAMILA-DIAS, C., GONCALVES, R., MAGRO, F., ASSOCIATION OF PORTUGUESE PATIENTS WITH, I. B. D. & PORTUGUESE STUDY GROUP OF, I. B. D. (2015). Assessing overall patient satisfaction in inflammatory bowel disease using structural equation modeling. Eur J Gastroenterol Hepatol, 27 (8), 941-50. http://www.ncbi.nlm.nih.gov/pubmed/25966672

69. SOARES-DA-SILVA, P., CABRAL, J. M., MAGALHAES, D., FRAGA, S. & MAGRO, F. (2015). Amine neurotransmitters, inflammation and epithelial sodium transport. Exp Physiol, in press http://www.ncbi.nlm.nih.gov/pubmed/26548358

70. SOUSA, J. B., VIEIRA-ROCHA, M. S., ARRIBAS, S. M., GONZALEZ, M. C., FRESCO, P. & DINIZ, C. (2015). Endothelial and Neuronal Nitric Oxide Activate Distinct Pathways on Sympathetic Neurotransmission in Rat Tail and Mesenteric Arteries. PLoS One, 10 (6), e0129224. http://www.ncbi.nlm.nih.gov/pubmed/26075386

71. SPERLING, M. R., ABOU-KHALIL, B., HARVEY, J., ROGIN, J. B., BIRABEN, A., GALIMBERTI, C. A., KOWACS, P. A., HONG, S. B., CHENG, H., BLUM, D., NUNES, T., SOARES-DA-SILVA, P. & STUDY, T. (2015). Eslicarbazepine acetate as adjunctive therapy in patients with uncontrolled partial-onset seizures: Results of a phase III, double-blind, randomized, placebo-controlled trial. Epilepsia, 56 (2), 244-53. http://www.ncbi.nlm.nih.gov/pubmed/25528898

72. VAN DER WOUDE, C. J., ARDIZZONE, S., BENGTSON, M. B., FIORINO, G., FRASER, G., KATSANOS, K., KOLACEK, S., JUILLERAT, P., MULDERS, A. G., PEDERSEN, N., SELINGER, C., SEBASTIAN, S., STURM, A., ZELINKOVA, Z., MAGRO, F., EUROPEAN, C. S. & COLITIS, O. (2015). The second European evidenced-based consensus on reproduction and pregnancy in inflammatory bowel disease. J Crohns Colitis, 9 (2), 107-24. http://www.ncbi.nlm.nih.gov/pubmed/25602023

73. VAZ-DA-SILVA, M., ROCHA, J. F., LACROIX, P., FALCAO, A., ALMEIDA, L. & SOARES-DA-SILVA, P. (2015). Cardiac safety profile of etamicastat, a novel peripheral selective dopamine-β-hydroxylase inhibitor in non-human primates, human young and elderly healthy volunteers and hypertensive patients. IJC Metabolic & Endocrine, 7 10-24. http://www.sciencedirect.com/science/article/pii/S2214762415000134

74. VEGH, Z., BURISCH, J., PEDERSEN, N., KAIMAKLIOTIS, I., DURICOVA, D., BORTLIK, M., VINDING, K. K., AVNSTROM, S., OLSEN, J., NIELSEN, K. R., KATSANOS, K. H., TSIANOS, E. V., LAKATOS, L., SCHWARTZ, D., ODES, S., D'INCA, R., BELTRAMI, M., KIUDELIS, G., KUPCINSKAP, L., JUCOV, A., TURCAN, S., BARROS, L. F., MAGRO, F., LAZAR, D., GOLDIS, A., DE CASTRO, L., HERNANDEZ, V., NIEWIADOMSKI, O., BELL, S., LANGHOLZ, E., MUNKHOLM, P., LAKATOS, P. L. & EPICOM, G. (2015). Treatment Steps, Surgery, and Hospitalization Rates During the First Year of Follow-up in Patients with Inflammatory Bowel Diseases from the 2011 ECCO-Epicom Inception Cohort. J Crohns Colitis, 9 (9), 747-53. http://www.ncbi.nlm.nih.gov/pubmed/26055976

75. VIEIRA, L., SILVESTRE-FERREIRA, A. C., FONTES-SOUSA, A. P., BALREIRA, A. C., MORCHON, R., CARRETON, E., VILHENA, H., SIMON, F. & MONTOYA-ALONSO, J. A. (2015). Seroprevalence of heartworm (Dirofilaria immitis) in feline and canine hosts from central and northern Portugal. J Helminthol, 89 (5), 625-9. http://www.ncbi.nlm.nih.gov/pubmed/24824176

2014 (articles in alphabetical order)

1. AZEVEDO, A. R., DE SOUSA, H. M., MONTEIRO, J. A. & LIMA, A. R. (2014). Future perspectives of Smartphone applications for rheumatic diseases self-management. Rheumatol Int, 35 419-31. http://www.ncbi.nlm.nih.gov/pubmed/25168866

2. BARROS, J., COSTA-RODRIGUES, J., LOPES, M. A., PINA-VAZ, I. & FERNANDES, M. H. (2014). Response of Human Osteoblastic and Osteoclastic Cells to AH Plus and Pulp Canal Sealer Containing Quaternary Ammonium Polyethylenimine Nanoparticles. J Endod, 40 (8), 1149-55. http://www.ncbi.nlm.nih.gov/pubmed/25069923

3. BONIFACIO, M. J., SUTCLIFFE, J. S., TORRAO, L., WRIGHT, L. C. & SOARES-DA-SILVA, P. (2014). Brain and peripheral pharmacokinetics of levodopa in the cynomolgus monkey following administration of opicapone, a third generation nitrocatechol COMT inhibitor. Neuropharmacology, 77 334-41. http://www.ncbi.nlm.nih.gov/pubmed/24148813

4. BURISCH, J., PEDERSEN, N., CUKOVI, X. C. S., BRINAR, M., KAIMAKLIOTIS, I., DURICOVA, D., SHONOVA, O., VIND, I., AVNSTROM, S., THORSGAARD, N., ANDERSEN, V., KRABBE, S., DAHLERUP, J. F., SALUPERE, R., NIELSEN, K. R., OLSEN, J., MANNINEN, P., COLLIN, P., TSIANOS, E. V., KATSANOS, K. H., LADEFOGED, K., LAKATOS, L., BJORNSSON, E., RAGNARSSON, G., BAILEY, Y., ODES, S., SCHWARTZ, D., MARTINATO, M., LUPINACCI, G., MILLA, M., DE PADOVA, A., D'INCA, R., BELTRAMI, M., KUPCINSKAS, L., KIUDELIS, G., TURCAN, S., TIGHINEANU, O., MIHU, I., MAGRO, F., BARROS, L. F., GOLDIS, A., LAZAR, D., BELOUSOVA, E., NIKULINA, I., HERNANDEZ, V., MARTINEZ-ARES, D., ALMER, S., ZHULINA, Y., HALFVARSON, J., AREBI, N., SEBASTIAN, S., LAKATOS, P. L., LANGHOLZ, E., MUNKHOLM, P. & FOR THE, E.-G. (2014). East-West gradient in the incidence of inflammatory bowel disease in Europe: the ECCO-EpiCom inception cohort. Gut, 63 (4), 588-597. http://www.ncbi.nlm.nih.gov/pubmed/23604131

5. BURISCH, J., PEDERSEN, N., CUKOVIC-CAVKA, S., TURK, N., KAIMAKLIOTIS, I., DURICOVA, D., BORTLIK, M., SHONOVA, O., VIND, I., AVNSTROM, S., THORSGAARD, N., KRABBE, S., ANDERSEN, V., DAHLERUP, J. F., KJELDSEN, J., SALUPERE, R., OLSEN, J., NIELSEN, K. R., MANNINEN, P., COLLIN, P., KATSANOS, K. H., TSIANOS, E. V., LADEFOGED, K., LAKATOS, L., RAGNARSSON, G., BJORNSSON, E., BAILEY, Y., O'MORAIN, C., SCHWARTZ, D., ODES, S., GIANNOTTA, M., GIRARDIN, G., KIUDELIS, G., KUPCINSKAS, L., TURCAN, S., BARROS, L., MAGRO, F., LAZAR, D., GOLDIS, A., NIKULINA, I., BELOUSOVA, E., MARTINEZ-ARES, D., HERNANDEZ, V., ALMER, S., ZHULINA, Y., HALFVARSON, J., AREBI, N., TSAI, H. H., SEBASTIAN, S., LAKATOS, P. L., LANGHOLZ, E., MUNKHOLM, P. & EPICOM, G. (2014). Environmental factors in a population-based inception cohort of inflammatory bowel disease patients in Europe - An ECCO-EpiCom study. J Crohns Colitis, 8 (7), 607-16. http://www.ncbi.nlm.nih.gov/pubmed/24315795

6. BURISCH, J., PEDERSEN, N., CUKOVIC-CAVKA, S., TURK, N., KAIMAKLIOTIS, I., DURICOVA, D., SHONOVA, O., VIND, I., AVNSTROM, S., THORSGAARD, N., KRABBE, S., ANDERSEN, V., DAHLERUP JENS, F., KJELDSEN, J., SALUPERE, R., OLSEN, J., NIELSEN, K. R., MANNINEN, P., COLLIN, P., KATSANOS, K. H., TSIANOS, E. V., LADEFOGED, K., LAKATOS, L., BAILEY, Y., O'MORAIN, C., SCHWARTZ, D., ODES, S., MARTINATO, M., LOMBARDINI, S., JONAITIS, L., KUPCINSKAS, L., TURCAN, S., BARROS, L., MAGRO, F., LAZAR, D., GOLDIS, A., NIKULINA, I., BELOUSOVA, E., FERNANDEZ, A., HERNANDEZ, V., ALMER, S., ZHULINA, Y., HALFVARSON, J., TSAI, H. H., SEBASTIAN, S., LAKATOS, P. L., LANGHOLZ, E., MUNKHOLM, P. & EPICOM, G. (2014). Initial disease course and treatment in an inflammatory bowel disease inception cohort in Europe: the ECCO-EpiCom cohort. Inflamm Bowel Dis, 20 (1), 36-46. http://www.ncbi.nlm.nih.gov/pubmed/24252978

7. BURISCH, J., VEGH, Z., PEDERSEN, N., CUKOVIC-CAVKA, S., TURK, N., KAIMAKLIOTIS, I., DURICOVA, D., BORTLIK, M., SHONOVA, O., THORSGAARD, N., KRABBE, S., ANDERSEN, V., DAHLERUP, J. F., KJELDSEN, J., SALUPERE, R., OLSEN, J., NIELSEN, K. R., MANNINEN, P., COLLIN, P., KATSANOS, K. H., TSIANOS, E. V., LADEFOGED, K., RAGNARSSON, G., BJORNSSON, E., BAILEY, Y., O'MORAIN, C., SCHWARTZ, D., ODES, S., POLITI, P., SANTINI, A., KIUDELIS, G., KUPCINSKAS, L., TURCAN, S., MAGRO, F., BARROS, L., LAZAR, D., GOLDIS, A., NIKULINA, I., BELOUSOVA, E., SANROMAN, L., MARTINEZ-ARES, D., ALMER, S., ZHULINA, Y., HALFVARSON, J., AREBI, N., HOUSTON, Y., SEBASTIAN, S., LANGHOLZ, E., LAKATOS, P. L., MUNKHOLM, P. & EPICOM, G. (2014). Health care and patients' education in a European inflammatory bowel disease inception cohort: An ECCO-EpiCom study. J Crohns Colitis, 8 (8), 811-8. http://www.ncbi.nlm.nih.gov/pubmed/24439390

8. BURISCH, J., WEIMERS, P., PEDERSEN, N., CUKOVIC-CAVKA, S., VUCELIC, B., KAIMAKLIOTIS, I., DURICOVA, D., BORTLIK, M., SHONOVA, O., VIND, I., AVNSTROM, S., THORSGAARD, N., KRABBE, S., ANDERSEN, V., DAHLERUP, J. F., KJELDSEN, J., SALUPERE, R., OLSEN, J., NIELSEN, K. R., MANNINEN, P., COLLIN, P., KATSANOS, K. H., TSIANOS, E. V., LADEFOGED, K., LAKATOS, L., RAGNARSSON, G., BJORNSSON, E., BAILEY, Y., O'MORAIN, C., SCHWARTZ, D., ODES, S., VALPIANI, D., BONI, M. C., JONAITIS, L., KUPCINSKAS, L., TURCAN, S., BARROS, L., MAGRO, F., LAZAR, D., GOLDIS, A., NIKULINA, I., BELOUSOVA, E., FERNANDEZ, A., SANROMAN, L., ALMER, S., ZHULINA, Y., HALFVARSON, J., AREBI, N., DIGGORY, T., SEBASTIAN, S., LAKATOS, P. L., LANGHOLZ, E., MUNKHOLM, P. & EPICOM, G. (2014). Health-related quality of life improves during one year of medical and surgical treatment in a European population-based inception cohort of patients with Inflammatory Bowel Disease - An ECCO-EpiCom study. J Crohns Colitis, 8 (9), 1030-42. http://www.ncbi.nlm.nih.gov/pubmed/24560877

9. CARNEIRO, I., TIMOTEO, M. A., SILVA, I., VIEIRA, C., BALDAIA, C., FERREIRINHA, F., SILVA-RAMOS, M. & CORREIA-DE-SA, P. (2014). Activation of P2Y6 receptors increases the voiding frequency in anaesthetized rats by releasing ATP from the bladder urothelium. Br J Pharmacol, 171 (14), 3404-19. http://www.ncbi.nlm.nih.gov/pubmed/24697602

10. CORREIA-SA, I., SERRAO, P., MARQUES, M. & VIEIRA-COELHO, M. A. (2014). Vitamin D and Inflammatory Biomarkers during Wound-Healing. Plast Reconstr Surg, 134 (4 Suppl 1), 68-9. http://www.ncbi.nlm.nih.gov/pubmed/25254772

11. COSTA, M., GARCIA, M., COSTA-RODRIGUES, J., COSTA, M. S., RIBEIRO, M. J., FERNANDES, M. H., BARROS, P., BARREIRO, A., VASCONCELOS, V. & MARTINS, R. (2014). Exploring bioactive properties of marine cyanobacteria isolated from the Portuguese coast: high potential as a source of anticancer compounds. Mar Drugs, 12 (1), 98-114. http://www.ncbi.nlm.nih.gov/pubmed/24384871

12. DE PAULA RAMOS, E., ANTONIO, M. B., AMBIEL, C. R., CORREIA-DE-SA, P. & ALVES-DO-PRADO, W. (2014). Paradoxical neostigmine-induced TOFfade: On the role of presynaptic cholinergic and adenosine receptors. Eur J Pharmacol, 723 389-96. http://www.ncbi.nlm.nih.gov/pubmed/24247035

13. DIGNASS, A., ELIAKIM, R., MAGRO, F., MAASER, C., CHOWERS, Y., GEBOES, K., MANTZARIS, G., REINISCH, W., COLOMBEL, J., VERMEIRE, S., TRAVIS, S., LINDSAY, J. O. & VAN ASSCHE, G. (2014). Second European evidence-based Consensus on the diagnosis and management of ulcerative colitis Part 1: Definitions and diagnosis (Spanish version). Rev Gastroenterol Mex, 79 (4), 263-289. http://www.ncbi.nlm.nih.gov/pubmed/25487134

14. DOESER, A., SOARES-DA-SILVA, P., BECK, H. & UEBACHS, M. (2014). The effects of eslicarbazepine on persistent Na(+) current and the role of the Na(+) channel beta subunits. Epilepsy Res, 108 (2), 202-11. http://www.ncbi.nlm.nih.gov/pubmed/24368131

15. DUNANT, Y. & CORDEIRO, J. M. (2014). Presynaptic k(+) channels, vesicular ca(2+)/h (+) antiport-synaptotagmin, and acetylcholinesterase, three mechanisms cutting short the cholinergic signal at neuromuscular and nerve-electroplaque junctions. J Mol Neurosci, 53 (3), 377-86. http://www.ncbi.nlm.nih.gov/pubmed/24390960

16. DURAO, S. F., GOMES, P. S., COLACO, B. J., SILVA, J. C., FONSECA, H. M., DUARTE, J. R., FELINO, A. C. & FERNANDES, M. H. (2014). The biomaterial-mediated healing of critical size bone defects in the ovariectomized rat. Osteoporos Int, 25 (5), 1535-45. http://www.ncbi.nlm.nih.gov/pubmed/24573401

17. ELIAKIM, R. & MAGRO, F. (2014). Imaging techniques in IBD and their role in follow-up and surveillance. Nat Rev Gastroenterol Hepatol, 11 (12), 722-36. http://www.ncbi.nlm.nih.gov/pubmed/25157623

18. FREITAS, E. & GUIMARAES, J. (2014). Neuromyelitis optica spectrum disorders associated with other autoimmune diseases. Rheumatol Int, 35 (2), 243-53. http://www.ncbi.nlm.nih.gov/pubmed/24952418

19. GONCALVES, A. P., CORDEIRO, J. M., MONTEIRO, J., MUNOZ, A., CORREIA-DE-SA, P., READ, N. D. & VIDEIRA, A. (2014). Activation of a TRP-like channel and intracellular Ca2+ dynamics during phospholipase-C-mediated cell death. J Cell Sci, 127 (Pt 17), 3817-3829. http://www.ncbi.nlm.nih.gov/pubmed/25037570

20. GRUNZE, H., KOTLIK, E., COSTA, R., NUNES, T., FALCAO, A., ALMEIDA, L. & SOARES-DA-SILVA, P. (2014). Assessment of the efficacy and safety of eslicarbazepine acetate in acute mania and prevention of recurrence: Experience from multicentre, double-blind, randomised phase II clinical studies in patients with bipolar disorder I. J Affect Disord, 174C 70-82. http://www.ncbi.nlm.nih.gov/pubmed/25484179

21. GUIMARAES, J., VIEIRA-COELHO, M. A., MOURA, E., AFONSO, J., ROSAS, M. J., VAZ, R. & GARRETT, C. (2014). Urinary profile of catecholamines and metabolites in Parkinson patients with deep brain stimulation. Eur J Neurol, 21 (2), 353-6. http://www.ncbi.nlm.nih.gov/pubmed/23679894

22. KISS, L. E. & SOARES-DA-SILVA, P. (2014). Medicinal chemistry of catechol O-methyltransferase (COMT) inhibitors and their therapeutic utility. J Med Chem, 57 (21), 8692-717. http://www.ncbi.nlm.nih.gov/pubmed/25080080

23. LANGNER, C., MAGRO, F., DRIESSEN, A., ENSARI, A., MANTZARIS, G. J., VILLANACCI, V., BECHEANU, G., BORRALHO NUNES, P., CATHOMAS, G., FRIES, W., JOURET-MOURIN, A., MESCOLI, C., DE PETRIS, G., RUBIO, C. A., SHEPHERD, N. A., VIETH, M., ELIAKIM, R. & GEBOES, K. (2014). The histopathological approach to inflammatory bowel disease: a practice guide. Virchows Arch, 464 (5), 511-27. http://www.ncbi.nlm.nih.gov/pubmed/24487791

24. LARANJEIRA, M. S., CARVALHO, A., PELAEZ-VARGAS, A., FERNANDES, M. H., HANSFORD, D. & MONTEIRO, F. J. (2014). Modulation of human dermal microvascular endothelial cells (HDMEC) and human gingival fibroblast (HGF) behaviors by micropatterned silica coating surfaces for zirconia dental implants applications. Sci. Technol. Adv. Mater., 15 (2), 025001 (11pp). http://iopscience.iop.org/1468-6996/15/2/025001/

25. LIMA, A., SOUSA, H., MONTEIRO, J., AZEVEDO, R., MEDEIROS, R. & SEABRA, V. (2014). Genetic polymorphisms in low-dose methotrexate transporters: current relevance as methotrexate therapeutic outcome biomarkers. Pharmacogenomics, 15 (12), 1611-35. http://www.ncbi.nlm.nih.gov/pubmed/25340735

26. LOUREIRO, A. I., JOAO BONIFACIO, M., FERNANDES-LOPES, C., IGREJA, B., WRIGHT, L. C. & SOARES-DA-SILVA, P. (2014). Etamicastat, a new dopamine-ss-hydroxylase inhibitor, pharmacodynamics and metabolism in rat. Eur J Pharmacol, 740 285-94. http://www.ncbi.nlm.nih.gov/pubmed/25058908

27. LOUREIRO, A. I., ROCHA, J. F., FERNANDES-LOPES, C., NUNES, T., WRIGHT, L. C., ALMEIDA, L. & SOARES-DA-SILVA, P. (2014). Human disposition, metabolism and excretion of etamicastat, a reversible, peripherally selective dopamine beta-hydroxylase inhibitor. Br J Clin Pharmacol, 77 (6), 1017-26. http://www.ncbi.nlm.nih.gov/pubmed/24168152

28. MAGINA, S., VIEIRA-COELHO, M. A., MOURA, E., SERRAO, M. P., PISCITELLI, F., MOURA, D. & DI MARZO, V. (2014). Effect of narrowband ultraviolet B treatment on endocannabinoid plasma levels in patients with psoriasis. Br J Dermatol, 171 (1), 198-201. http://www.ncbi.nlm.nih.gov/pubmed/24641781

29. MAGRO, F. & ABREU, C. (2014). Immunisations in Crohn’s disease: Who? Why? What? When? Best Practice & Research Clinical Gastroenterology, 28 (3), 485-96. http://www.sciencedirect.com/science/article/pii/S1521691814000511#

30. MAGRO, F. & ELIAKIM, R. (2014). Are we on our way to change our mode of thinking and treating inflammatory bowel disease patients? Ann Gastroenterol, 27 (4), 424-426. http://www.ncbi.nlm.nih.gov/pubmed/25330804

31. MAGRO, F., PEYRIN-BIROULET, L., SOKOL, H., ALDEGER, X., COSTA, A., HIGGINS, P. D., JOYCE, J. C., KATSANOS, K. H., LOPEZ, A., DE XAXARS, T. M., TOADER, E. & BEAUGERIE, L. (2014). Extra-intestinal malignancies in inflammatory bowel disease: results of the 3rd ECCO Pathogenesis Scientific Workshop (III). J Crohns Colitis, 8 (1), 31-44. http://www.ncbi.nlm.nih.gov/pubmed/23721759

32. MAGRO, F., RODRIGUES-PINTO, E., COELHO, R., ANDRADE, P., SANTOS-ANTUNES, J., LOPES, S., CAMILA-DIAS, C. & MACEDO, G. (2014). Is it Possible to Change Phenotype Progression in Crohn's Disease in the Era of Immunomodulators? Predictive Factors of Phenotype Progression. Am J Gastroenterol, 109 (7), 1026-36. http://www.ncbi.nlm.nih.gov/pubmed/24796767

33. MAGRO, F., RODRIGUES-PINTO, E., LOPES, S. & MACEDO, G. (2014). Earlier need of infliximabintensification in Ulcerative Colitisthan in Crohn's disease. J Crohns Colitis, 8 (10), 1331-2. http://www.ncbi.nlm.nih.gov/pubmed/24690137

34. MAGRO, F., RODRIGUES-PINTO, E., SANTOS-ANTUNES, J., VILAS-BOAS, F., LOPES, S., NUNES, A., CAMILA-DIAS, C. & MACEDO, G. (2014). High C-reactive protein in Crohn's disease patients predicts nonresponse to infliximab treatment. J Crohns Colitis, 8 (2), 129-36. http://www.ncbi.nlm.nih.gov/pubmed/23932786

35. MAGRO, F., SANTOS-ANTUNES, J., VILAS-BOAS, F., RODRIGUES-PINTO, E., COELHO, R., RIBEIRO, O. S., LOPES, S. & MACEDO, G. (2014). Crohn's disease outcome in patients under azathioprine: A tertiary referral center experience. J Crohns Colitis, 8 (7), 617-25. http://www.ncbi.nlm.nih.gov/pubmed/24332869

36. MAGRO, F., SOARES, J. B. & FERNANDES, D. (2014). Venous thrombosis and prothrombotic factors in inflammatory bowel disease. World J Gastroenterol, 20 (7), 4857-72. http://www.wjgnet.com/1007-9327/current.htm

37. MAGRO, F., SOUSA, P. & MINISTRO, P. (2014). C-reactive protein in Crohn's disease: how informative is it? Expert Rev Gastroenterol Hepatol, 8 (4), 393-408. http://www.ncbi.nlm.nih.gov/pubmed/24635486

38. MATA, D., OLIVEIRA, F. J., FERREIRA, N. M., ARAUJO, R. F., FERNANDES, A. J., LOPES, M. A., GOMES, P. S., FERNANDES, M. H. & SILVA, R. F. (2014). Processing strategies for smart electroconductive carbon nanotube-based bioceramic bone grafts. Nanotechnology, 25 (14), 145602. http://www.ncbi.nlm.nih.gov/pubmed/24622290

39. MATA, D., OLIVEIRA, F. J., FERRO, M., GOMES, P. S., FERNANDES, M. H., LOPES, M. A. & SILVA, R. F. (2014). Multifunctional Carbon Nanotube/Bioceramics Modulate the Directional Growth and Activity of Osteoblastic Cells. Journal of Biomedical Nanotechnology, 10 (5), 725-43. http://www.ingentaconnect.com/content/asp/jbn/2014/00000010/00000005/art00001

40. MOREIRA-RODRIGUES, M., GRACA, A. L., FERREIRA, M., AFONSO, J., SERRAO, P., MORATO, M., FERREIRINHA, F., CORREIA-DE-SA, P., EBERT, S. N. & MOURA, D. (2014). Attenuated Aortic Vasodilation and Sympathetic Prejunctional Facilitation in Epinephrine-Deficient Mice: Selective Impairment of beta2-Adrenoceptor Responses. J Pharmacol Exp Ther, 351 (2), 243-9. http://www.ncbi.nlm.nih.gov/pubmed/25161169

41. NAZARETH, N., MAGRO, F., SILVA, J., DURO, M., GRACIO, D., COELHO, R., APPELBERG, R., MACEDO, G. & SARMENTO, A. (2014). Infliximab therapy increases the frequency of circulating CD16+ monocytes and modifies macrophage cytokine response to bacterial infection. Clin Exp Immunol, 177 (3), 703-11. http://www.ncbi.nlm.nih.gov/pubmed/24816497

42. NORONHA-MATOS, J. B., COIMBRA, J., SA, E. S. A., ROCHA, R., MARINHAS, J., FREITAS, R., GUERRA-GOMES, S., FERREIRINHA, F., COSTA, M. A. & CORREIA-DE-SA, P. (2014). P2X7-induced zeiosis promotes osteogenic differentiation and mineralization of postmenopausal bone marrow-derived mesenchymal stem cells. FASEB J, 28 (12), 5208-22. http://www.ncbi.nlm.nih.gov/pubmed/25169056

43. OLIVEIRA, A., PINHO, D., ALBINO-TEIXEIRA, A., MEDEIROS, R., DINIS-OLIVEIRA, R. J. & CARVALHO, F. (2014). Morphine glucuronidation increases its analgesic effect in guinea pigs. Life Sci, 109 (2), 104-10. http://www.ncbi.nlm.nih.gov/pubmed/24968302

44. OLIVEIRA, L., COSTA, A. C., NORONHA-MATOS, J. B., SILVA, I., CAVALCANTE, W. L., TIMOTEO, M. A., CORRADO, A. P., DAL BELO, C. A., AMBIEL, C. R., ALVES-DO-PRADO, W. & CORREIA-DE-SA, P. (2014). Amplification of neuromuscular transmission by methylprednisolone involves activation of presynaptic facilitatory adenosine A receptors and redistribution of synaptic vesicles. Neuropharmacology, 89C 64-76. http://www.ncbi.nlm.nih.gov/pubmed/25220030

45. OSORIO, F., PEDROSA, A., AZEVEDO, F., FIGUEIREDO, P. & MAGINA, S. (2014). Cat-scratch disease during anti-tumor necrosis factor-alpha therapy: case report and review of the literature. Int J Dermatol, 53 (3), e182-3. http://www.ncbi.nlm.nih.gov/pubmed/23557494

46. PALMAS, R. A., MONTEIRO, J. & FRESCO, P. (2014). Analytical methods fortaxanes quantification in diluted formulations and biological samples and their applications in clinical practice. International Journal of Pharmacy and Pharmaceutical Sciences, 6 (6), 17-23. http://www.ijppsjournal.com/Vol6Issue6/8298.pdf

47. PEREIRA, C., LOPES-RODRIGUES, V., COUTINHO, I., NEVES, M. P., LIMA, R. T., PINTO, M., CIDADE, H., VASCONCELOS, M. H. & SARAIVA, L. (2014). Potential small-molecule activators of caspase-7 identified using yeast-based caspase-3 and -7 screening assays. Eur J Pharm Sci, 54 8-16. http://www.ncbi.nlm.nih.gov/pubmed/24398107

48. PEREIRA, C., MIGUEL MARTINS, L. & SARAIVA, L. (2014). LRRK2, but not pathogenic mutants, protects against HO stress depending on mitochondrial function and endocytosis in a yeast model. Biochim Biophys Acta, 1840 (6), 2025-2031. http://www.ncbi.nlm.nih.gov/pubmed/24576675

49. POPOV, S., TAKEMORI, H., TOKUDOME, T., MAO, Y., OTANI, K., MOCHIZUKI, PIRES, N., PINHO, M. J., FRANCO-CERECEDA, A., TORIELLI, L., FERRANDI, M., HAMSTEN, A., SOARES-DA-SILVA, P., ERIKSSON, P., BERTORELLO, A. M. & BRION, L. (2014). Lack of salt-inducible kinase 2 (SIK2) prevents the development of cardiac hypertrophy in response to chronic high-salt intake. PLoS ONE, 9 (4), e95771. http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0095771

50. POTSCHKA, H., SOERENSEN, J., PEKCEC, A., LOUREIRO, A. & SOARES-DA-SILVA, P. (2014). Effect of eslicarbazepine acetate in the corneal kindling progression and the amygdala kindling model of temporal lobe epilepsy. Epilepsy Res, 108 (2), 212-22. http://www.ncbi.nlm.nih.gov/pubmed/24345645

51. QUINTAS, C., PINHO, D., PEREIRA, C., SARAIVA, L., GONCALVES, J. & QUEIROZ, G. (2014). Microglia P2Y6 receptors mediate nitric oxide release and astrocyte apoptosis. J Neuroinflammation, 11 (1), 141. http://www.ncbi.nlm.nih.gov/pubmed/25178395

52. RAHIER, J. F., MAGRO, F., ABREU, C., ARMUZZI, A., BEN-HORIN, S., CHOWERS, Y., COTTONE, M., DE RIDDER, L., DOHERTY, G., EHEHALT, R., ESTEVE, M., KATSANOS, K., LEES, C. W., MACMAHON, E., MOREELS, T., REINISCH, W., TILG, H., TREMBLAY, L., VEEREMAN-WAUTERS, G., VIGET, N., YAZDANPANAH, Y., ELIAKIM, R., COLOMBEL, J. F., ON BEHALF OF THE EUROPEAN, C. S. & COLITIS, O. (2014). Second European evidence-based consensus on the prevention, diagnosis and management of opportunistic infections in inflammatory bowel disease. J Crohns Colitis, 8 (6), 443-68. http://www.ncbi.nlm.nih.gov/pubmed/24613021

53. REBELO, T., COSTA-RODRIGUES, J., SANTOS, C., FERNANDES, M. H., NORONHA, J. & SALES, G. (2014). Novel Prostate Specific Antigen plastic antibody designed with charged binding sites for an improved protein binding and its application in a biosensor of potentiometric transduction. Electrochimica Acta, 132 142-150. http://ac.els-cdn.com/S0013468614006215/1-s2.0-S0013468614006215-main.pdf?_tid=3ca3244a-ca02-11e3-b28a-00000aab0f27&acdnat=1398159850_10c548418770fc09d1635d426e16a45a

54. REBELO, T. S. C. R., PEREIRA, C. M., SALES, M. F., NORONHA, J. P., COSTA-RODRIGUES, J., SILVA, F. & FERNANDES, M. H. (2014). Sarcosine oxidase composite screen-printed electrode for sarcosine determination in biological samples. Analytica Chimica Acta, 850 26-32. http://www.sciencedirect.com/science/article/pii/S0003267014009520

55. REINA-COUTO, M., CARVALHO, J., VALENTE, M. J., VALE, L., AFONSO, J., CARVALHO, F., BETTENCOURT, P., SOUSA, T. & ALBINO-TEIXEIRA, A. (2014). Impaired resolution of inflammation in human chronic heart failure. Eur J Clin Invest, 44 (6), 527-38. http://www.ncbi.nlm.nih.gov/pubmed/24673112

56. RIBEIRO, V., GARCIA, M., OLIVEIRA, R., GOMES, P. S., COLACO, B. & FERNANDES, M. H. (2014). Bisphosphonates induce the osteogenic gene expression in co-cultured human endothelial and mesenchymal stem cells. J Cell Mol Med, 18 (1), 27-37. http://www.ncbi.nlm.nih.gov/pubmed/24373581

57. RIEDER, F., DE BRUYN, J. R., PHAM, B. T., KATSANOS, K., ANNESE, V., HIGGINS, P. D., MAGRO, F. & DOTAN, I. (2014). Results of the 4th Scientific Workshop of the ECCO (Group II): Markers of intestinal fibrosis in inflammatory bowel disease. J Crohns Colitis, 8 (10), 1166-1178. http://www.ncbi.nlm.nih.gov/pubmed/24726695

58. ROCHA, J. F., FALCAO, A., SANTOS, A., PINTO, R., LOPES, N., NUNES, T., WRIGHT, L. C., VAZ-DA-SILVA, M. & SOARES-DA-SILVA, P. (2014). Effect of opicapone and entacapone upon levodopa pharmacokinetics during three daily levodopa administrations. Eur J Clin Pharmacol, 70 (9), 1059-71. http://www.ncbi.nlm.nih.gov/pubmed/24925090

59. ROCHA, J. F., SANTOS, A., FALCAO, A., LOPES, N., NUNES, T., PINTO, R. & SOARES-DA-SILVA, P. (2014). Effect of moderate liver impairment on the pharmacokinetics of opicapone. Eur J Clin Pharmacol, 70 (3), 279-86. http://www.ncbi.nlm.nih.gov/pubmed/24271646

60. RODRIGUES, C., COSTA-RODRIGUES, J., CAPELAS, J. A. & FERNANDES, M. H. (2014). Behaviour of co-cultured human osteoclastic and osteoblastic cells exposed to endodontic sealers' extracts. Clin Oral Investig, 18 (2), 479-88. http://www.ncbi.nlm.nih.gov/pubmed/23604699

61. RODRIGUES, L. R., DE LARANJEIRA, M. S., FERNANDES, M. H., MONTEIRO, F. J. & DE CARVALHO ZAVAGLIA, C. A. (2014). HA/TCP scaffolds obtained by sucrose crystal leaching method: Preliminary in vitro evaluation. Materials Research, 17 (4), 811-16. http://www.scielo.br/scielo.php?pid=S1516-14392014000400003&script=sci_arttext

62. RODRIGUES-PINTO, E., MAGRO, F., PIMENTA, S., GUIMARAES, J. & MACEDO, G. (2014). Mimicry between intestinal Behcet's disease and inflammatory bowel disease. J Crohns Colitis, 8 (7), 714-5. http://www.ncbi.nlm.nih.gov/pubmed/24389388

63. SANTOS, J. M., BENITE-RIBEIRO, S. A., QUEIROZ, G. & DUARTE, J. A. (2014). The interrelation between aPKC and glucose uptake in the skeletal muscle during contraction and insulin stimulation. Cell Biochem Funct, 32 (8), 621-4. http://www.ncbi.nlm.nih.gov/pubmed/25529429

64. SANTOS-ANTUNES, J., ABREU, C., MAGRO, F., COELHO, R., VILAS-BOAS, F., ANDRADE, P., LOPES, S. & MACEDO, G. (2014). Disseminated cutaneous herpes simplex infection in a patient with Crohn's disease under azathioprine and steroids: First case report and literature review. J Crohns Colitis, 8 (4), 326-30. http://www.ncbi.nlm.nih.gov/pubmed/24257435

65. SANTOS-ANTUNES, J., MAGRO, F. & MACEDO, G. (2014). Listeria monocytogenes bacteremia and CMV colitis in a patient with Ulcerative Colitis. J Crohns Colitis, 8 (3), 254-5. http://www.ncbi.nlm.nih.gov/pubmed/24183232

66. SANTOS-MORAIS, D., COELHO, J., FERRAZ, M. P., GOMES, P. S., FERNANDES, M. H., HUSSAIN, N. S., SANTOSA, J. D. & LOPESA, M. A. (2014). Samarium doped glass-reinforced hydroxyapatite with enhanced osteoblastic performance and antibacterial properties for bone tissue regeneration. Journal of Materials Chemistry B, 2 5872-81. http://pubs.rsc.org/en/Content/ArticleLanding/2014/TB/C4TB00484A#!divAbstract

67. SOARES, A. S., COSTA, V. M., DINIZ, C. & FRESCO, P. (2014). Combination of Cl-IB-MECA with paclitaxel is a highly effective cytotoxic therapy causing mTOR-dependent autophagy and mitotic catastrophe on human melanoma cells. J Cancer Res Clin Oncol, 140 (6), 921-935. http://www.ncbi.nlm.nih.gov/pubmed/24659394

68. SOARES, A. S., COSTA, V. M., DINIZ, C. & FRESCO, P. (2014). The combination of Cl-IB-MECA with paclitaxel: a new anti-metastatic therapeutic strategy for melanoma. Cancer Chemother Pharmacol, 74 (4), 847-60. http://www.ncbi.nlm.nih.gov/pubmed/25119183

69. SOARES, J., PEREIRA, N. A., MONTEIRO, A., LEAO, M., BESSA, C., DOS SANTOS, D. J., RAIMUNDO, L., QUEIROZ, G., BISIO, A., INGA, A., PEREIRA, C., SANTOS, M. M. & SARAIVA, L. (2014). Oxazoloisoindolinones with in vitro antitumor activity selectively activate a p53-pathway through potential inhibition of the p53-MDM2 interaction. Eur J Pharm Sci, 66 138-47. http://www.ncbi.nlm.nih.gov/pubmed/25312347

70. SOUSA, J. B., FRESCO, P. & DINIZ, C. (2014). Endothelial dysfunction impairs vascular neurotransmission in tail arteries. Neurochem Int, 80C 7-13. http://www.ncbi.nlm.nih.gov/pubmed/25447765

71. SOUSA, J. B., VIEIRA-ROCHA, M. S., SA, C., FERREIRINHA, F., CORREIA-DE-SA, P., FRESCO, P. & DINIZ, C. (2014). Lack of endogenous adenosine tonus on sympathetic neurotransmission in spontaneously hypertensive rat mesenteric artery. PLoS One, 9 (8), e105540. http://www.ncbi.nlm.nih.gov/pubmed/25158061

72. TIMOTEO, M. A., CARNEIRO, I., SILVA, I., NORONHA-MATOS, J. B., FERREIRINHA, F., SILVA-RAMOS, M. & CORREIA-DE-SA, P. (2014). ATP released via pannexin-1 hemichannels mediates bladder overactivity triggered by urothelial P2Y6 receptors. Biochem Pharmacol, 87 (2), 371-9. http://www.ncbi.nlm.nih.gov/pubmed/24269631

73. VEGH, Z., BURISCH, J., PEDERSEN, N., KAIMAKLIOTIS, I., DURICOVA, D., BORTLIK, M., AVNSTROM, S., VINDING, K. K., OLSEN, J., NIELSEN, K. R., KATSANOS, K. H., TSIANOS, E. V., LAKATOS, L., SCHWARTZ, D., ODES, S., LUPINACCI, G., DE PADOVA, A., JONAITIS, L., KUPCINSKAS, L., TURCAN, S., TIGHINEANU, O., MIHU, I., BARROS, L. F., MAGRO, F., LAZAR, D., GOLDIS, A., FERNANDEZ, A., HERNANDEZ, V., NIEWIADOMSKI, O., BELL, S., LANGHOLZ, E., MUNKHOLM, P., LAKATOS, P. L. & EPICOM, G. (2014). Incidence and initial disease course of inflammatory bowel diseases in 2011 in Europe and Australia: results of the 2011 ECCO-EpiCom inception cohort. J Crohns Colitis, 8 (11), 1506-15. http://www.ncbi.nlm.nih.gov/pubmed/24998983

74. VIDAL, H., GONÇALINHO, H., MONTEIRO, J., DAS NEVES, J., SARMENTO, B., DINIZ, C. & FRESCO, P. (2014). Development and validation of a rapid and simple reversed-phase HPLC method for the determination of gemcitabine in human plasma. International Journal of Pharmacy and Pharmaceutical Sciences, 6 (9), 59-65. http://innovareacademics.in/journals/index.php/ijpps/article/view/8447

75. VIEIRA, C., MAGALHÃES-CARDOSO, M. T., FERREIRINHA, F., SILVA, I., DIAS, A. S., PELLETIER, J., SÉVIGNY, J. & CORREIA-DE-SÁ, P. (2014). Feed-Forward Inhibition of CD73 and Upregulation of Adenosine Deaminase Contribute to the Loss of Adenosine Neuromodulation in Postinflammatory Ileitis. Mediators of Inflammation, 2014 (2014), Article ID 254640, 19 pages. http://www.hindawi.com/journals/mi/2014/254640/

76. VIEIRA, L., SILVESTRE-FERREIRA, A. C., FONTES-SOUSA, A. P., BALREIRA, A. C., MORCHON, R., CARRETON, E., VILHENA, H., SIMON, F. & MONTOYA-ALONSO, J. A. (2014). Seroprevalence of heartworm (Dirofilaria immitis) in feline and canine hosts from central and northern Portugal. J Helminthol, 89 (5), 625-9. http://www.ncbi.nlm.nih.gov/pubmed/24824176

2013 (articles in alphabetical order)

1. ABREU, C., MAGRO, F., SANTOS-ANTUNES, J., PILAO, A., RODRIGUES-PINTO, E., BERNARDES, J., BERNARDO, A., MAGINA, S., VILAS-BOAS, F., LOPES, S., MACEDO, G. & SARMENTO, A. (2013). Tuberculosis in anti-TNF-alpha treated patients remains a problem in countries with an intermediate incidence: analysis of 25 patients matched with a control population. J Crohns Colitis, 7 (10), e486-92. http://www.ncbi.nlm.nih.gov/pubmed/23583099

2. ABREU, C., MAGRO, F., VILAS-BOAS, F., LOPES, S., MACEDO, G. & SARMENTO, A. (2013). Listeria infection in patients on anti-TNF treatment: report of two cases and review of the literature. J Crohns Colitis, 7 (2), 175-82. http://www.ncbi.nlm.nih.gov/pubmed/22626505

3. AFONSO, J., PASSOS, C. P., COIMBRA, M. A., SILVA, C. M. & SOARES-DA-SILVA, P. (2013). Inhibitory effect of phenolic compounds from grape seeds (Vitis vinifera L.) on the activity of angiotensin I converting enzyme. Lwt-Food Science and Technology, 54 (1), 265-270. <Go to ISI>://000321991200039

4. ALMEIDA, L., NUNES, T., COSTA, R., ROCHA, J. F., VAZ-DA-SILVA, M. & SOARES-DA-SILVA, P. (2013). Etamicastat, a novel dopamine beta-hydroxylase inhibitor: tolerability, pharmacokinetics, and pharmacodynamics in patients with hypertension. Clin Ther, 35 (12), 1983-96. http://www.ncbi.nlm.nih.gov/pubmed/24296323

5. ALMEIDA, L., ROCHA, J. F., FALCAO, A., PALMA, P. N., LOUREIRO, A. I., PINTO, R., BONIFACIO, M. J., WRIGHT, L. C., NUNES, T. & SOARES-DA-SILVA, P. (2013). Pharmacokinetics, pharmacodynamics and tolerability of opicapone, a novel catechol-O-methyltransferase inhibitor, in healthy subjects: prediction of slow enzyme-inhibitor complex dissociation of a short-living and very long-acting inhibitor. Clinical pharmacokinetics, 52 (2), 139-51. http://www.ncbi.nlm.nih.gov/pubmed/23248072

6. ARAUJO, J. R., CORREIA-BRANCO, A., PEREIRA, A. C., PINHO, M. J., KEATING, E. & MARTEL, F. (2013). Oxidative stress decreases uptake of neutral amino acids in a human placental cell line (BeWo cells). Reprod Toxicol, 40 76-81. http://www.ncbi.nlm.nih.gov/pubmed/23806338

7. ARAUJO, J. R., CORREIA-BRANCO, A., RAMALHO, C., GONCALVES, P., PINHO, M. J., KEATING, E. & MARTEL, F. (2013). L-methionine placental uptake: characterization and modulation in gestational diabetes mellitus. Reprod Sci, 20 (12), 1492-507. http://www.ncbi.nlm.nih.gov/pubmed/23653387

8. BESSA, C., PEREIRA, C., LEAO, M., MACIEL, C., GOMES, S., GONCALVES, J., CORTE-REAL, M., COSTA, V. & SARAIVA, L. (2013). Using yeast to uncover the regulation of protein kinase Cdelta by ceramide. FEMS Yeast Res, 13 (7), 700-5. http://www.ncbi.nlm.nih.gov/pubmed/23937324

9. BURISCH, J., PEDERSEN, N., CUKOVIC-CAVKA, S., BRINAR, M., KAIMAKLIOTIS, I., DURICOVA, D., SHONOVA, O., VIND, I., AVNSTROM, S., THORSGAARD, N., ANDERSEN, V., KRABBE, S., DAHLERUP, J. F., SALUPERE, R., NIELSEN, K. R., OLSEN, J., MANNINEN, P., COLLIN, P., TSIANOS, E. V., KATSANOS, K. H., LADEFOGED, K., LAKATOS, L., BJORNSSON, E., RAGNARSSON, G., BAILEY, Y., ODES, S., SCHWARTZ, D., MARTINATO, M., LUPINACCI, G., MILLA, M., DE PADOVA, A., D'INCA, R., BELTRAMI, M., KUPCINSKAS, L., KIUDELIS, G., TURCAN, S., TIGHINEANU, O., MIHU, I., MAGRO, F., BARROS, L. F., GOLDIS, A., LAZAR, D., BELOUSOVA, E., NIKULINA, I., HERNANDEZ, V., MARTINEZ-ARES, D., ALMER, S., ZHULINA, Y., HALFVARSON, J., AREBI, N., SEBASTIAN, S., LAKATOS, P. L., LANGHOLZ, E., MUNKHOLM, P. & FOR THE, E.-G. (2013). East-West gradient in the incidence of inflammatory bowel disease in Europe: the ECCO-EpiCom inception cohort. Gut, http://www.ncbi.nlm.nih.gov/pubmed/23604131

10. BURISCH, J., PEDERSEN, N., CUKOVIC-CAVKA, S., TURK, N., KAIMAKLIOTIS, I., DURICOVA, D., BORTLIK, M., SHONOVA, O., VIND, I., AVNSTROM, S., THORSGAARD, N., KRABBE, S., ANDERSEN, V., DAHLERUP, J. F., KJELDSEN, J., SALUPERE, R., OLSEN, J., NIELSEN, K. R., MANNINEN, P., COLLIN, P., KATSANOS, K. H., TSIANOS, E. V., LADEFOGED, K., LAKATOS, L., RAGNARSSON, G., BJORNSSON, E., BAILEY, Y., O'MORAIN, C., SCHWARTZ, D., ODES, S., GIANNOTTA, M., GIRARDIN, G., KIUDELIS, G., KUPCINSKAS, L., TURCAN, S., BARROS, L., MAGRO, F., LAZAR, D., GOLDIS, A., NIKULINA, I., BELOUSOVA, E., MARTINEZ-ARES, D., HERNANDEZ, V., ALMER, S., ZHULINA, Y., HALFVARSON, J., AREBI, N., TSAI, H. H., SEBASTIAN, S., LAKATOS, P. L., LANGHOLZ, E., MUNKHOLM, P. & FOR THE, E.-G. (2013). Environmental factors in a population-based inception cohort of inflammatory bowel disease patients in Europe - An ECCO-EpiCom study. J Crohns Colitis, http://www.ncbi.nlm.nih.gov/pubmed/24315795

11. CABRAL, J. M., SOARES-DA-SILVA, P. & MAGRO, F. (2013). Short- and long-term regulation of intestinal Na+/H+ exchange activity associated with TLR2 receptor activation is independent of nuclear factor-kappaB signaling. J Pharmacol Exp Ther, 346 (3), 453-64. http://www.ncbi.nlm.nih.gov/pubmed/23845891

12. CORDEIRO, J. M., BODA, B., GONCALVES, P. P. & DUNANT, Y. (2013). Synaptotagmin 1 is required for vesicular Ca(2)(+)/H(+)-antiport activity. J Neurochem, 126 (1), 37-46. http://www.ncbi.nlm.nih.gov/pubmed/23607712

13. CORREIA-DE-SA, P., NORONHA-MATOS, J. B., TIMOTEO, M. A., FERREIRINHA, F., MARQUES, P., SOARES, A. M., CARVALHO, C., CAVALCANTE, W. L. & GALLACCI, M. (2013). Bothropstoxin-I reduces evoked acetylcholine release from rat motor nerve terminals: radiochemical and real-time video-microscopy studies. Toxicon, 61 16-25. http://www.ncbi.nlm.nih.gov/pubmed/23142504

14. CORREIA-SA, I., DE-SOUSA-LOPES, H., MARTINS, M. J., AZEVEDO, I., MOURA, E. & VIEIRA-COELHO, M. A. (2013). Effects of raftilose on serum biochemistry and liver morphology in rats fed with normal or high-fat diet. Mol Nutr Food Res, 57 (8), 1468-72. http://www.ncbi.nlm.nih.gov/pubmed/23653231

15. COSTA, J., MAGRO, F., CALDEIRA, D., ALARCAO, J., SOUSA, R. & VAZ-CARNEIRO, A. (2013). Infliximab reduces hospitalizations and surgery interventions in patients with inflammatory bowel disease: a systematic review and meta-analysis. Inflamm Bowel Dis, 19 (10), 2098-110. http://www.ncbi.nlm.nih.gov/pubmed/23860567

16. COSTA-RODRIGUES, J., REIS, S., TEIXEIRA, S., LOPES, S. & FERNANDES, M. H. (2013). Dose-dependent inhibitory effects of proton pump inhibitors on human osteoclastic and osteoblastic cell activity. FEBS J, 280 (20), 5052-64. http://www.ncbi.nlm.nih.gov/pubmed/23937530

17. DIAS, C. C., RODRIGUES, P. P., DA COSTA-PEREIRA, A. & MAGRO, F. (2013). Clinical prognostic factors for disabling Crohn's disease: a systematic review and meta-analysis. World J Gastroenterol, 19 (24), 3866-71. http://www.ncbi.nlm.nih.gov/pubmed/23840127

18. DURAES, C., MACHADO, J. C., PORTELA, F., RODRIGUES, S., LAGO, P., CRAVO, M., MINISTRO, P., MARQUES, M., CREMERS, I., FREITAS, J., COTTER, J., TAVARES, L., MATOS, L., MEDEIROS, I., SOUSA, R., RAMOS, J., DEUS, J., CALDEIRA, P., CHAGAS, C., DUARTE, M. A., GONCALVES, R., LOUREIRO, R., BARROS, L., BASTOS, I., CANCELA, E., MORAES, M. C., MOREIRA, M. J., VIEIRA, A. I. & MAGRO, F. (2013). Phenotype-genotype profiles in Crohn's disease predicted by genetic markers in autophagy-related genes (GOIA study II). Inflamm Bowel Dis, 19 (2), 230-9. http://www.ncbi.nlm.nih.gov/pubmed/22573572

19. ELGER, C., BIALER, M., FALCAO, A., VAZ-DA-SILVA, M., NUNES, T., ALMEIDA, L. & SOARES-DA-SILVA, P. (2013). Pharmacokinetics and tolerability of eslicarbazepine acetate and oxcarbazepine at steady state in healthy volunteers. Epilepsia, 54 (8), 1453-61. http://www.ncbi.nlm.nih.gov/pubmed/23758485

20. EUSEBIO, N., PINHEIRO, T., AMORIM, A. A., GAMBOA, F., SARAIVA, L., GUSMAO, L., AMORIM, A. & ARAUJO, R. (2013). SNaPaer: a practical single nucleotide polymorphism multiplex assay for genotyping of Pseudomonas aeruginosa. PLoS One, 8 (6), e66083. http://www.ncbi.nlm.nih.gov/pubmed/23776608

21. FALCAO, A., LIMA, R., SOUSA, R., NUNES, T. & SOARES-DA-SILVA, P. (2013). Bioequivalence of eslicarbazepine acetate from two different sources of its active product ingredient in healthy subjects. Drugs in R&D, 13 (2), 137-43. http://www.ncbi.nlm.nih.gov/pubmed/23677811

22. FALCAO, A., PINTO, R., NUNES, T. & SOARES-DA-SILVA, P. (2013). Effect of repeated administration of eslicarbazepine acetate on the pharmacokinetics of simvastatin in healthy subjects. Epilepsy research, 106 (1-2), 244-9. http://www.ncbi.nlm.nih.gov/pubmed/23726291

23. FALCAO, A., VAZ-DA-SILVA, M., GAMA, H., NUNES, T., ALMEIDA, L. & SOARES-DA-SILVA, P. (2013). Effect of eslicarbazepine acetate on the pharmacokinetics of a combined ethinylestradiol/levonorgestrel oral contraceptive in healthy women. Epilepsy Res, 105 (3), 368-76. http://www.ncbi.nlm.nih.gov/pubmed/23570863

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