Funding of MedInUP members

Description

2003

2004

2005

2006

2007

2008

2009

2010

2011

2012

Total

Pluriannual Programme/Strategic project

78.50

54.69

130.93

64.73

164.77

149.78

101.92

108.55

63.53

101.59

1019.04

FCT-funded projects

270.30

115.95

296.38

384.15

166.28

298.36

315.07

376.44

446.49

392.41

3061.87

European Commission-funded projects

0.00

0.00

0.00

0.00

0.00

0.00

0.00

0.00

0.00

0.00

0.00

Other international projects

0.00

0.00

0.00

0.00

3.00

0.00

0.00

3.50

0.00

0.00

6.50

Other national projects

12.50

3.15

6.25

25.22

27.00

23.08

32.73

27.98

18.73

35.00

207.66

National industry projects

0.00

0.00

0.00

0.00

0.00

0.00

0.00

0.00

0.00

20.00

20.00

International industry projects

0.00

0.00

0.00

0.00

0.00

0.00

0.00

0.00

0.00

0.00

0.00

TOTAL

361.30

173.79

433.56

474.11

361.06

471.23

449.73

516.48

528.76

549.01

4315.09

Research Projects of MedInUP members

Principal Investigator

Title

Reference

Ana Patrícia Fontes Sousa

On the role of adenosine signalling in the progression of pulmonary hypertension to heart failure

PTDC/DTP-FTO/0802/2012

António Albino Teixeira

Hypoalgesia associated with hypertension: mechanisms and role of renin-angiotensin system activation

POCTI/NSE/45409/2002

António Albino Teixeira

Hypertension-associated hypoalgesia

PP-IJUP2005

António Albino Teixeira

Effect of angiotensin II administration on caudal ventrolateral medulla upon pain perception and blood pressure

ECVS2006

António Albino Teixeira

Acute effects of vasoconstrictor and vasodilator drugs on the blood pressure of rats

ECVS2008-15

António Albino Teixeira

Effect of angiotensin II administration on caudal ventrolateral medulla upon pain perception and blood pressure

ECVS2008-16

António Albino Teixeira

Influence of caffeine intake on the blood pressure and renal function of hypertensive rats

ECVS2008-17

António Albino Teixeira

An experimental model of diabetes

ECVS2008-18

António Albino Teixeira

Influence of caffeine on the blood pressure and renal function of hypertensive rats

ECVS2009-8

António Albino Teixeira

Diabetes, arterial hypertension and neuropathic pain

ECVS2009-12

António Albino Teixeira

Study of the renal function in an experimental model of diabetic nephropathy

ECVS2009-13

António Albino Teixeira

Effect of arterial hypertension in the renal antioxidant defenses in Rat

ECVS2009-16

António Albino Teixeira

Arterial hypertension, kidney and antioxidant defenses

ECVS2010-13

António Albino Teixeira

Influence of caffeine on the blood pressure and renal function of hypertensive rats

ECVS2010-14

António Albino Teixeira

Painful diabetic neuropathy: studies in na animal model of diabetes

ECVS2010-15

António Albino Teixeira

Relationship between cardiovascular and pain control systems: genetic manipulation of NMDA receptors in central nervous system

ECVS2010-16

António Albino Teixeira

Childhood obesity-related inflammation and vascular injury - Impact on the kidney

PTDC/DTP-PIC/0239/2012

Carmen Diniz

Caracterização imuno-histoquímica e funcional da distribuição de receptores de adenosina no sistema cardiovascular em ratos normais e hipertensos

Reitoria da UP e Fundação Ilídio Pinho

Carmen Diniz

Rational development of new A3 receptor ligands as new therapeutic approaches in cancer

 Projetos Pluridisciplinares apoiados pela CGD e UP

Carmen Diniz

Characterization of adenosine receptors in mesenteric artery in their putative role in hypertensionProtective role of adenosine in inflammatory processes: devolpmente of new therapeutic strategies

E-73/10   - Fundação das Universidades Portuguesas – Acções Integradas Luso-Espanholas

Daniel Moura

Crosstalk between bradykinin and an unknown agent (angiotensin II?)  on the endothelial  control of heart function and arterial vasomotricity

POCTI/SAU/14294/2001

Daniel Moura

Development of a fibre-optic biosensor for catecholamine assay (CATSENSOR)

PTDC/QUI/70970/2006

Daniel Moura

Receptor cross-activation by rosiglitazone and angiotensin II receptor ligands in preadipocytes and sympathetic nerve endings of the rat heart

PP-IJUP2007

Daniel Moura

Characterization of atypical angiotensin II receptors in the Neuro-2A cell line

PP-IJUP2006

Daniel Moura

Cross activation of PPAR-gamma and AT-1 receptores in preadipocytes and sympathetice nerves

PP-IJUP2008

Dora Pinho

Hypertension and painful diabetic neuropathy. Role of angiotensin II and oxidative stress in central nervous system

PTDC/SAU-NEU/101090/2008

Dora Pinho

Painful diabetic neuropathy under hypertensive conditions in Rat: role of the spinal oxidative stress

PP-IJUP2009-99

Dora Pinho

Reactive oxygen species in painful diabetic neuropathy

ECVS2011-3

Dora Pinho

Reactive oxygen species in painful diabetic neuropathy

ECVS2012-13

Fátima Ferreirinha

Sinalização purinérgica numa nova sinapse mioentérica tripartda: relevância funcional

Universidade do Porto / Banco Santander Totta - Programa de Investigação Científica na Pré-Graduação

Fernando Magro

Regulatory effects of pattern recognition receptors (PRRs) in electrolyte transport and m em brane potential in intestinal epithelial cells

PTDC/SAU-TOX/117664/2010

FFUP-REQUIMTE Participant Institution

GALENO - Modelação e controlo para administração personalizada de fármacos

PTDC/SAU-BEB/103367/2008

FMDUP, Participant Institution

Desenvolvimento de uma plataforma em nanoescala para o enriquecimento de proteases

EXPL/BBB-BEP/0317/2012

FMDUP, Participant Institution

Silicon nitride ceramic components coated with nanocrystalline CVD diamond for total hip replacement” (FMDUP, Participant Institution)

PTDC/EME-PME/112910/2009

FMDUP, Participant Institution

Influence of physical activity on bone tissue quality of female Wistar rats with estrogen deficiency

PTDC/DES/103047/2008

FMDUP, Participant Institution

Bone response to nanostructured and micropatterned surface modified Zirconia dental implants

PTDC/CTM/100120/2008

FMDUP, Participant Institution

Antibacterial and osteogenic behaviour of modified calcium phosphate (MCP): in vitro and in vivo evaluation

PTDC/SAU-BEB/103034/2008

FMDUP, Participant Institution

Marine cyanobacteria isolated from the portuguese coast as a source of bioactive compounds: cytotoxicity against human tumour cells and normal human cells

PTDC/MAR/102638/2008

FMDUP, Participant Institution

Termoterapia altamente focalizada de tumores sólidos usando um cimento ferrimagnético injectável

PTDC/SAU-BEB/69497/2006

FMDUP, Participant Institution

Nova geração de biomateriais bioactivos e biorreabsorvíveis para cirurgia regenerativa do tecido ósseo utilizando biomodelização 3-D

POCI/CTM/59091/2004

Glória Queiroz

Papel dos recetores P2 na comunicação neuronal e neurónio-astrócito

POCTI/SAU-FCF/60714/2004

Glória Queiroz 

Modulação purinérgica da comunicação astrócito-micróglia na astrogliose

PTDC/SAU-TOX/115597/2009

Glória Queiroz 

Purinergic regulation of noradrenaline level in cortical synapses

 Projetos Pluridisciplinares apoiados pelo Banco Santander Totta e UP

Glória Queiroz 

Regulation by microglia of nucleotide induced astrgliosis: mechanisms involved

 Projetos Pluridisciplinares apoiados pelo Banco Santander Totta e UP

Ines Sá

The endocannabinoid system in pathogenesis of dermal fibrosis

Prémio Fundação Amélia de Mello

João Miguel Cordeiro

A adenosina na modulação do transporte de GABA e de glutamato em doentes com MTLE

Universidade do Porto / Banco Santander Totta - Programa de Investigação Científica na Pré-Graduação

Laura Oliveira

Is there a place for adenosine mediating impairment of both neuromuscular and immunological synapses in myasthenics?

PTDC/SAU-FCF/108462/2008

Lucília Saraiva

Functional, molecular and pharmacological studies of p53 family proteins: from yeast to human cells

PTDC/SAU-FAR/110848/2009

Lucília Saraiva

FUNCTIONAL AND PHARMACOLOGICAL STUDIES OF P53 FAMILY PROTEINS: SCREENING FOR SELECTIVE SMALL-MOLECULE MODULATORS

 Projetos Pluridisciplinares apoiados pelo Banco Santander Totta e UP

Lúcilia Saraiva

SEARCHING FOR SMALL-MOLECULE MODULATORS OF CASPASE FAMILY MEMBERS USING YEAST CELL-BASED APPROACHES

 Projetos Pluridisciplinares apoiados pelo Banco Santander Totta e UP

Lúcilia Saraiva

MODELING AND MANAGING FUNGAL COLONIZATION AND INFLAMMATORY PROGRESSION ON CYSTIC FIBROSIS PATIENTS

 Projetos Pluridisciplinares apoiados pelo Banco Santander Totta e UP

Lúcilia Saraiva

Using yeast-based functional assays for the study of p53 signalling pathway, pharmacological screening and molecular characterization of small-molecules targeting p53 function

 Projetos Pluridisciplinares apoiados pela CGD e UP

Manuela Morato

Interplay between adenosine and angiotensin II and glomerular injury in Diabetes with associated Hypertension: a putative new therapeutic target?

PTDC/SAU-FCF/67764/2006

Manuela Morato

Does adenosine modulate the effect of enalapril on the proliferation and extacellular matrix production of rat glomerular mesangial cells?

 Projetos Pluridisciplinares apoiados pelo Banco Santander Totta e UP

Manuela Morato

Effect of adenosine on cell proliferation and production of extracellular matrix and angiotensin II in rat glomerular mesangial cells exposed to high-glucose

 Projetos Pluridisciplinares apoiados pelo Banco Santander Totta e UP

Maria Augusta Vieira Coelho

Adrenergic modulation in Intestinal Transport of Electrolytes in Hypertension

POCTI/FCB/40832/2001

Maria Augusta Vieira Coelho

alpha2C adrenoceptors in the adrenal medulla and cardiovascular profile

PTDC/SAL-FCF/66502/2006

Maria Augusta Vieira Coelho

Characterization of alph2a-adrenoceptor subtype  involved in adrenal  control release of catecholamines in knock-out mice for each adrenoceptor subtype

PP-IJUP2006

Maria Augusta Vieira Coelho

Influence of prebiotics in the diet and alkaline phosphatase activity in liver morphology

PP-IJUP2006

Maria Augusta Vieira Coelho

Synthesis and metabolism of catecholamines in the brain of mice knock out for the alpha 2C adrenoceptor

ECVS2006

Maria Helena Fernandes

A new generation of biodegradable implants obtained from magnesium alloys functionalized by means of advanced surface treatment

ERA-MNT/0002/2009

Maria Helena Fernandes

Osteoporosis influence in the biomaterial-mediated bone regeneration process – in vitro and in vivo studies

 Universidade do Porto/Caixa Geral de Depósitos

Maria Helena Fernandes

Modelos in vitro para avaliação do potencial de angiogénese de substitutos ósseos

 Universidade do Porto/Caixa Geral de Depósitos

Maria Helena Fernandes

Estudo experimental e modelagem matemática e computacional do mecanismo de remodelação óssea

Project 249/09, Program CAPES/FCT

Maria Helena Fernandes

New generation of biomimetic and customized implants for bone engineering

COST Action MP 1301; 2013-2016

Maria João Pinho

Regulation of Dopamine D3 Receptor Expression and Function in the Pathogenesis of Hypertension

PP-IJUP2011-42

Mónica Rodrigues

Role of adrenaline on the maturation of the different beta-adrenoceptor subtypes

PP-IJUP2012-

Mónica Rodrigues

"PNMT knockout and knockdown to identify the role of adrenaline on the maturation of β-adrenoceptors in neonates"

Prémio Prof. Ernesto Morais

Patrício Soares da Silva

Oxidative stress and genetic markers of cardiovascular risk in hypertension

PIC/IC/83204/2007

Patrício Soares da Silva

Antinatriuretic agents and the renal bicarbonate handling in hypertension

POCI/SAU-FCF/59207/2004

Patrício Soares da Silva

Genomic and non-genomic regulation of LAT2 in genetic models of hypertension

POCI/SAU-OBS/57916/2004

Patrício Soares da Silva

Study of renal dopaminergic system in heart failure

POCTI/CBO/42788/2001

Patrício Soares da Silva

Renal tubular vectorial sodium transport and regulatory mechanisms

POCTI/CBO/45767/2002

Patrício Soares da Silva

Dopamine and sodium handling in immortalised renal tubular epithelial cells from Spontaneous Hypertensive Rats (SHR) and Wistar Kyoto (WKY) rats

POCTI/FCB/35747/2000

Patrício Soares da Silva

Role of dopamine and 5-hidroxytryptamine on water and electrolyte metabolism in human and rat inflamatory bowel disease

POCTI/SAU/14010/2001

Paula Fresco

The protective role of adenosine in vascular inflammation: molecular mechanisms and clinical implications

POCI/SAU-FCF/60782/2004

Paula Fresco

Desenvolvimento e validação de um modelo farmacocinético/farmacodinâmico para a individualização das doses de carboplatina e gemcitabina a administrar em doentes idosos com carcinoma do pulmão de não pequenas células avançado

PTDC/SAU-FCF/104448/2008

Paula Fresco

Protective role of adenosine in inflammatory processes: devolopment of new therapeutic strategies

E-44/07 - Fundação das Universidades Portuguesas – Acções Integradas Luso-Espanholas

Paulo Jorge Silva Correia Sá

Role of adenosine in neurotransmitter release and synaptic activity from myoneural, vascular and hippocampal synapses: Influence of calcium and of the stimulation paradigm

POCTI/36545/FCB/2000

Paulo Jorge Silva Correia Sá

Neuronal release of nucleotidases and their role in purinergic modulation of synaptic transmission

POCTI/FCB/45549/2002

Paulo Jorge Silva Correia Sá

Amplification of neuromuscular transmission by adenosine in mammals: New insight for treating myasthenic syndromes

POCTI/CVT/43368/2001

Paulo Jorge Silva Correia Sá

Purinergic modulation of cavernosal tissue from man with erectile dysfunction

Universidade do Porto / Fundação Ilídio Pinho - Programa de Investigação Científica na Pré-Graduação

Paulo Jorge Silva Correia Sá

HPLC analysis of the adenine nucleotides catabolism into adenosine regulating the release of neurotransmitters: Functional role of secreted nucleotidases

CONC-REEQ/1168/2001

Paulo Jorge Silva Correia Sá

Applications of confocal laser scanning microscopy to morphofunctional cell dynamics

CONC-REEQ/1264/2001

Paulo Jorge Silva Correia Sá

Papel das purinas extracelulares nos movimentos de Ca2+ e na proliferação de osteoblastos humanos em cultura

Universidade do Porto / Caixa Geral de Depósitos - Programa de Investigação Científica na Pré-Graduação.

Paulo Jorge Silva Correia Sá

Sinalização purinérgica em bexigas humanas com hiperactividade do detrusor por obstrução infravesical

Associação Portuguesa de Urologia

Paulo Jorge Silva Correia Sá

Papel das purinas no controlo mecano-sensitivo do detrusor humano como alvo pata o tratamento da bexiga hiperactiva

Associação Portuguesa de Urologia

Paulo Jorge Silva Correia Sá

Purinergic mechanosensory control as a new target for therapeutic intervention of overactive human bladder

Universidade do Porto / Caixa Geral de Depósitos - Programa de Investigação Científica na Pré-Graduação (IPG28/2007)

Paulo Jorge Silva Correia Sá

Purinergic characterization of human Sertoli Cells

Universidade do Porto / Caixa Geral de Depósitos - Programa de Investigação Científica na Pré-Graduação (IPG132/2007)

Paulo Jorge Silva Correia Sá

Origin and fate of extacellular purines regulating human bone formation

PTDC/SAU-OSM/73576/2006

Paulo Jorge Silva Correia Sá

Enteric purines as potential therapeutic targets for inflammatory bowel diseases

PTDC/CVT/74462/2006

Paulo Jorge Silva Correia Sá

Papel dos receptores da adenosina no crescimento e remodelação dos vasos cavernosos humanos: repercussão na fisiopatologia da disfunção eréctil vasculogénica

Sociedade Portuguesa de Andrologia / Bayer

Paulo Jorge Silva Correia Sá

Sinalização purinérgica no corpo cavernoso humano como alvo de intervenção farmacológica na disfunção eréctil de origem vasculogénica

Sociedade Portuguesa de Andrologia / Lilly

Paulo Jorge Silva Correia Sá

Papel dos receptors da adenosina no crescimento e remodelação dos vasos cavernosos humanos: Repercussão na fisiopatologia da disfunção eréctil vasculogénica

Universidade do Porto / Banco Santander Totta - Programa de Investigação Científica na Pré-Graduação

Paulo Jorge Silva Correia Sá

Pathophysiological role of purines (ATP and adenosine) in the human bladder hyperactivity

PTDC/SAU-OSM/104369/2008

Paulo Jorge Silva Correia Sá

Fibroblasts as mechano-sensory signalling intermediates between epithelia and primary afferent neurons: Role of extracellular ATP, purinoceptors and [Ca2+]i waves

PTDC/SAU-FCF/108263/2008

Paulo Jorge Silva Correia Sá

Toxin-induced myasthenia gravis and in vitro assays to characterize neuromuscular impairment: crosstalk between presynaptic adenosine and cholinergic receptors

Universidade do Porto / Banco Santander Totta - Programa de Investigação Científica na Pré-Graduação

Paulo Jorge Silva Correia Sá (PI: Berta Silva, UMIB/ICBAS)

Importância do HHV-6B na epilepsia do lobo temporal mesial (MTLE) com esclerose do hipocampo (HS): implicações na prevenção e tratamento

PIC/IC/83297/2007

Paulo Jorge Silva Correia Sá (PI: Carlos Melo Pereira, FCUP)

Biosensores para catecolaminas endógenas: Efeito de cristais líquidos na sensibilidade e selectividade

PTDC/QUI/69685/2006

Paulo Jorge Silva Correia Sá (PI: Madalena Pinto, FFUP)

Chiral xanthone derivatives: Synthesis, structural elucidation and biological activities

Universidade do Porto / Caixa Geral de Depósitos - Programa de Investigação Científica na Pré-Graduação (IPG11/2007)

Paulo Jorge Silva Correia Sá (PI: Rui Rangel, UMIB/ICBAS)

Actividade da ADK, ADA e NTPDases sobre os níveis de adenosina endógena no hipocampo e córtex temporal de doentes com MTLE

Liga Portuguesa contra a Epilepsia

Sofia Magina

The effect of ultraviolet phototherapy on endocannabinoids levels in patients with psoriasis

Prémio Pfizer

Teresa Sousa

Interaction of aspirin with antihypertensive drugs - impact on renal oxidative stress, inflammation, local renin-angiotensin system activation and blood pressure control

PTDC/SAU-TOX/114166/2009

Teresa Sousa

Evaluation of intra-renal renin-angiotensin system activation and oxidative stress in chronic heart failure

PP-IJUP2009-119

Teresa Sousa

Evaluation of an antioxidant treatment (catalase) in the expression of blood pressure regulatory enzymes

ECVS2011-4

Teresa Sousa

Evaluation of an antioxidant treatment (catalase) in the expression of blood pressure regulatory enzymes

ECVS2012-14

Teresa Sousa

Role of the activation of the renin-angiotensin system in vascular redox dysfunction

Prémio de Estímulo à Investigação - Fundação Calouste Gulbenkian

Teresa Sousa

Hydrogen peroxide (H2O2) production in two models of arterial hypertension with increased levels of angiotensin II

Prémio Jovem Investigador - Sociedade Portuguesa de Hipertensão