Outputs 2003-2012
In the last ten years (2003-2012) the MedInUP members supervised 103 PhD Thesis, and published 380 full manuscripts, 14 books and 48 book chapters (appendix I). A list of published full manuscripts is provided in appendix II.
Appendix I -Outputs of MedInUP members
|
Outputs of MedInUP members |
||||||||||||
|
Description |
2003 |
2004 |
2005 |
2006 |
2007 |
2008 |
2009 |
2010 |
2011 |
2012 |
Total |
Average |
|
No. of researchers |
20 |
21 |
22 |
32 |
37 |
40 |
42 |
42 |
46 |
68 |
370 |
37 |
|
No. of integrated researchers |
17 |
17 |
19 |
20 |
27 |
29 |
33 |
33 |
34 |
33 |
262 |
26 |
|
No. of technicians and administrative staff |
9 |
9 |
9 |
9 |
9 |
9 |
8 |
10 |
9 |
8 |
89 |
9 |
|
PhD thesis under the supervision of integrated members |
4 |
7 |
6 |
10 |
9 |
14 |
10 |
15 |
15 |
13 |
103 |
10 |
|
Publications in international peer reviewed journals |
21 |
30 |
29 |
29 |
24 |
39 |
46 |
52 |
59 |
51 |
380 |
38 |
|
Books |
1 |
1 |
1 |
2 |
3 |
3 |
0 |
2 |
1 |
0 |
14 |
1 |
|
Book chapters |
0 |
0 |
0 |
30 |
4 |
2 |
3 |
4 |
3 |
2 |
48 |
5 |
|
Models |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
|
Patents |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
3 |
3 |
0 |
|
Prototypes |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
|
Industry research contracts |
0 |
0 |
0 |
1 |
0 |
0 |
0 |
0 |
0 |
1 |
2 |
0 |
|
Research contracts with government bodies |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
|
Other research outputs |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
Appendix II - scientific publications by MedInUP members (2003-2012)
ALMEIDA, L. & SOARES-DA-SILVA, P. (2003). Pharmacokinetics and pharmacodynamics of BIA 3-202, a novel COMT inhibitor, during first administration to humans. Drugs R D, 4 (4), 207-17.
ALMEIDA, L. & SOARES-DA-SILVA, P. (2003). Safety, tolerability and pharmacokinetic profile of BIA 2-093, a novel putative antiepileptic agent, during first administration to humans. Drugs R D, 4 (5), 269-84.
ALMEIDA, L. & SOARES-DA-SILVA, P. (2003). Pharmacokinetic and pharmacodynamic profiles of BIA 3-202, a novel catechol-O-methyltransferase (COMT) inhibitor, during multiple-dose administration to healthy subjects. J Clin Pharmacol, 43 (12), 1350-60.
BONIFACIO, M. J. & SOARES-DA-SILVA, P. (2003). Purification of membrane-bound catechol-O-methyltransferase. Methods Mol Biol, 228 231-8.
BONIFACIO, M. J., VIEIRA-COELHO, M. A. & SOARES-DA-SILVA, P. (2003). Kinetic inhibitory profile of BIA 3-202, a novel fast tight-binding, reversible and competitive catechol-O-methyltransferase inhibitor. Eur J Pharmacol, 460 (2-3), 163-70.
COSTA, M. C., MAGALHAES, P., FERREIRINHA, F., GUIMARAES, L., JANUARIO, C., GASPAR, I., LOUREIRO, L., VALE, J., GARRETT, C., REGATEIRO, F., MAGALHAES, M., SOUSA, A., MACIEL, P. & SEQUEIROS, J. (2003). Molecular diagnosis of Huntington disease in Portugal: implications for genetic counselling and clinical practice. Eur J Hum Genet, 11 (11), 872-8.
FARIA, M., OLIVEIRA, L., TIMOTEO, M. A., LOBO, M. G. & CORREIA-DE-SA, P. (2003). Blockade of neuronal facilitatory nicotinic receptors containing alpha 3 beta 2 subunits contribute to tetanic fade in the rat isolated diaphragm. Synapse, 49 (2), 77-88.
GOMES, P. & SOARES-DA-SILVA, P. (2003). Dopamine D2-like receptor-mediated opening of K+ channels in opossum kidney cells. Br J Pharmacol, 138 (5), 968-76.
GUIMARAES, J. T., VINDIS, C., SOARES-DA-SILVA, P. & PARINI, A. (2003). Differential substrate specificity of monoamine oxidase in the rat heart and renal cortex. Life Sci, 73 (8), 955-67.
GUIMARAES, S., MORATO, M., SOUSA, T. & ALBINO-TEIXEIRA, A. (2003). Hypertension due to blockade of adenosine receptors. Pharmacology & Toxicology, 92 (4), 160-162.
LAM, R. S., APP, E. M., NAHIRNEY, D., SZKOTAK, A. J., VIEIRA-COELHO, M. A., KING, M. & DUSZYK, M. (2003). Regulation of Cl- secretion by alpha2-adrenergic receptors in mouse colonic epithelium. J Physiol, 548 (Pt 2), 475-84.
MAGALHAES-CARDOSO, M. T., PEREIRA, M. F., OLIVEIRA, L., RIBEIRO, J. A., CUNHA, R. A. & CORREIA-DE-SA, P. (2003). Ecto-AMP deaminase blunts the ATP-derived adenosine A2A receptor facilitation of acetylcholine release at rat motor nerve endings. J Physiol, 549 (Pt 2), 399-408.
MORATO, M., SOUSA, T., GUIMARAES, S., MOURA, D. & ALBINO-TEIXEIRA, A. (2003). Losartan and atenolol on hypertension induced by adenosine receptor blockade. Auton Autacoid Pharmacol, 23 (2), 133-40.
PALMA, P. N., BONIFACIO, M. J., LOUREIRO, A. I., WRIGHT, L. C., LEARMONTH, D. A. & SOARES-DA-SILVA, P. (2003). Molecular modeling and metabolic studies of the interaction of catechol-O-methyltransferase and a new nitrocatechol inhibitor. Drug Metab Dispos, 31 (3), 250-8.
PARADA, A. & SOARES-DA-SILVA, P. (2003). BIA 3-202, a novel catechol-O-methyltransferase inhibitor, reduces the peripheral O-methylation of L-DOPA and enhances its availability to the brain. Pharmacology, 68 (1), 29-37.
PINHO, M. J., GOMES, P., SERRAO, M. P., BONIFACIO, M. J. & SOARES-DA-SILVA, P. (2003). Organ-specific overexpression of renal LAT2 and enhanced tubular L-DOPA uptake precede the onset of hypertension. Hypertension, 42 (4), 613-8.
REBOLA, N., COELHO, J. E., COSTENLA, A. R., LOPES, L. V., PARADA, A., OLIVEIRA, C. R., SOARES-DA-SILVA, P., DE MENDONCA, A. & CUNHA, R. A. (2003). Decrease of adenosine A1 receptor density and of adenosine neuromodulation in the hippocampus of kindled rats. Eur J Neurosci, 18 (4), 820-8.
SAMPAIO-MAIA, B., SERRAO, P., VIEIRA-COELHO, M. A. & PESTANA, M. (2003). Differences in the renal dopaminergic system activity between Wistar rats from two suppliers. Acta Physiologica Scandinavica, 178 (1), 83-89.
SILVEIRA, P., VAZ-DA-SILVA, M., ALMEIDA, L., MAIA, J., FALCAO, A., LOUREIRO, A., TORRAO, L., MACHADO, R., WRIGHT, L. & SOARES-DA-SILVA, P. (2003). Pharmacokinetic-pharmacodynamic interaction between BIA 3-202, a novel COMT inhibitor, and levodopa/benserazide. Eur J Clin Pharmacol, 59 (8-9), 603-9.
SOARES-DA-SILVA, P., VIEIRA-COELHO, M. A. & PARADA, A. (2003). Catechol-O-methyltransferase inhibition in erythrocytes and liver by BIA 3-202 (1-[3,4-dibydroxy-5-nitrophenyl]-2-phenyl-ethanone). Pharmacol Toxicol, 92 (6), 272-8.
TIMOTEO, M. A., FARIA, M. & CORREIA-DE-SA, P. (2003). Endogenous adenosine prevents post-tetanic release facilitation mediated by alpha3beta2 nicotinic autoreceptors. Eur J Pharmacol, 464 (2-3), 115-25.
ALMEIDA, L. & SOARES-DA-SILVA, P. (2004). Safety, tolerability, and pharmacokinetic profile of BIA 2-093, a novel putative antiepileptic, in a rising multiple-dose study in young healthy humans. J Clin Pharmacol, 44 (8), 906-18.
ALMEIDA, L., VAZ-DA-SILVA, M., SILVEIRA, P., FALCAO, A., MAIA, J., LOUREIRO, A., TORRAO, L., MACHADO, R., WRIGHT, L. & SOARES-DA-SILVA, P. (2004). Pharmacokinetic-pharmacodynamic interaction between BIA 3-202, a novel COMT inhibitor, and levodopa/carbidopa. Clin Neuropharmacol, 27 (1), 17-24.
ALVELOS, M., FERREIRA, A., BETTENCOURT, P., SERRAO, P., PESTANA, M., CERQUEIRA-GOMES, M. & SOARES-DA-SILVA, P. (2004). The effect of dietary sodium restriction on neurohumoral activity and renal dopaminergic response in patients with heart failure. Eur J Heart Fail, 6 (5), 593-9.
ARAUJO, I. M., AMBROSIO, A. F., LEAL, E. C., VERDASCA, M. J., MALVA, J. O., SOARES-DA-SILVA, P., CARVALHO, A. P. & CARVALHO, C. M. (2004). Neurotoxicity induced by antiepileptic drugs in cultured hippocampal neurons: a comparative study between carbamazepine, oxcarbazepine, and two new putative antiepileptic drugs, BIA 2-024 and BIA 2-093. Epilepsia, 45 (12), 1498-505.
DUARTE-ARAUJO, M., NASCIMENTO, C., ALEXANDRINA TIMOTEO, M., MAGALHAES-CARDOSO, T. & CORREIA-DE-SA, P. (2004). Dual effects of adenosine on acetylcholine release from myenteric motoneurons are mediated by junctional facilitatory A(2A) and extrajunctional inhibitory A(1) receptors. Br J Pharmacol, 141 (6), 925-34.
DUARTE-ARAUJO, M., TIMOTEO, M. A. & CORREIA-DE-SA, P. (2004). Adenosine activating A(2A)-receptors coupled to adenylate cyclase/cyclic AMP pathway downregulates nicotinic autoreceptor function at the rat myenteric nerve terminals. Neurochem Int, 45 (5), 641-51.
FERREIRINHA, F., QUATTRINI, A., PIROZZI, M., VALSECCHI, V., DINA, G., BROCCOLI, V., AURICCHIO, A., PIEMONTE, F., TOZZI, G., GAETA, L., CASARI, G., BALLABIO, A. & RUGARLI, E. I. (2004). Axonal degeneration in paraplegin-deficient mice is associated with abnormal mitochondria and impairment of axonal transport. J Clin Invest, 113 (2), 231-42.
FRAGA, S., JOSE, P. A. & SOARES-DA-SILVA, P. (2004). Involvement of G protein-coupled receptor kinase 4 and 6 in rapid desensitization of dopamine D1 receptor in rat IEC-6 intestinal epithelial cells. Am J Physiol Regul Integr Comp Physiol, 287 (4), R772-9.
FRESCO, P., DINIZ, C. & GONCALVES, J. (2004). Facilitation of noradrenaline release by activation of adenosine A(2A) receptors triggers both phospholipase C and adenylate cyclase pathways in rat tail artery. Cardiovasc Res, 63 (4), 739-46.
GOMES, P. & SOARES-DA-SILVA, P. (2004). Dopamine acutely decreases type 3 Na+/H+ exchanger activity in renal OK cells through the activation of protein kinases A and C signalling cascades. Eur J Pharmacol, 488 (1-3), 51-9.
GUIMARAES, S., CARNEIRO, C., BRANDAO, F., PINHEIRO, H., ALBINO-TEIXEIRA, A. & MOURA, D. (2004). A pharmacological differentiation between postjunctional (AT1A) and prejunctional (AT1B) angiotensin II receptors in the rabbit aorta. Naunyn Schmiedebergs Arch Pharmacol, 370 (4), 262-9.
LEARMONTH, D. A., PALMA, P. N., VIEIRA-COELHO, M. A. & SOARES-DA-SILVA, P. (2004). Synthesis, biological evaluation, and molecular modeling studies of a novel, peripherally selective inhibitor of catechol-O-methyltransferase. J Med Chem, 47 (25), 6207-17.
MAGRO, F., ARAUJO, F., PEREIRA, P., MEIRELES, E., DINIZ-RIBEIRO, M. & VELOSOM, F. T. (2004). Soluble selectins, sICAM, sVCAM, and angiogenic proteins in different activity groups of patients with inflammatory bowel disease. Dig Dis Sci, 49 (7-8), 1265-74.
MAGRO, F., FRAGA, S., RIBEIRO, T. & SOARES-DA-SILVA, P. (2004). Intestinal Na+-K+-ATPase activity and molecular events downstream of interferon-gamma receptor stimulation. Br J Pharmacol, 142 (8), 1281-92.
MAGRO, F., FRAGA, S., RIBEIRO, T. & SOARES-DA-SILVA, P. (2004). Decreased availability of intestinal dopamine in transmural colitis may relate to inhibitory effects of interferon-gamma upon L-DOPA uptake. Acta Physiol Scand, 180 (4), 379-86.
MARTEL, F., MONTEIRO, R., LEMOS, C. & VIEIRA-COELHO, M. A. (2004). In vitro and in vivo effect of fluoxetine on the permeability of 3H-serotonin across rat intestine. Can J Physiol Pharmacol, 82 (11), 940-50.
OLIVEIRA, L., TIMOTEO, M. A. & CORREIA-DE-SA, P. (2004). Tetanic depression is overcome by tonic adenosine A(2A) receptor facilitation of L-type Ca(2+) influx into rat motor nerve terminals. J Physiol, 560 (Pt 1), 157-68.
PEDROSA, R., GOMES, P., HOPFER, U., JOSE, P. A. & SOARES-DA-SILVA, P. (2004). Gialpha3 protein-coupled dopamine D3 receptor-mediated inhibition of renal NHE3 activity in SHR proximal tubular cells is a PLC-PKC-mediated event. Am J Physiol Renal Physiol, 287 (5), F1059-66.
PEDROSA, R., GOMES, P. & SOARES-DA-SILVA, P. (2004). Distinct signalling cascades downstream to Gsalpha coupled dopamine D1-like NHE3 inhibition in rat and opossum renal epithelial cells. Cell Physiol Biochem, 14 (1-2), 91-100.
PEDROSA, R., GOMES, P., ZENG, C., HOPFER, U., JOSE, P. A. & SOARES-DA-SILVA, P. (2004). Dopamine D3 receptor-mediated inhibition of Na+/H+ exchanger activity in normotensive and spontaneously hypertensive rat proximal tubular epithelial cells. Br J Pharmacol, 142 (8), 1343-53.
PEDROSA, R., JOSE, P. A. & SOARES-DA-SILVA, P. (2004). Defective D1-like receptor-mediated inhibition of the Cl-/HCO3- exchanger in immortalized SHR proximal tubular epithelial cells. Am J Physiol Renal Physiol, 286 (6), F1120-6.
PESTANA, M., SANTOS, J., SANTOS, A., COROAS, A., CORREIA, F., SERRAO, P., VALBUENA, C. & SOARES-DA-SILVA, P. (2004). Renal dopamine and salt sensitivity of blood pressure in IgA nephropathy. Kidney Blood Press Res, 27 (2), 78-87.
PINHO, D., BESSON, S., BRONDINO, C. D., DE CASTRO, B. & MOURA, I. (2004). Copper-containing nitrite reductase from Pseudomonas chlororaphis DSM 50135. Eur J Biochem, 271 (12), 2361-9.
PINHO, D., BESSON, S., BRONDINO, C. D., PEREIRA, E., DE CASTRO, B. & MOURA, I. (2004). Two azurins with unusual redox and spectroscopic properties isolated from the Pseudomonas chlororaphis strains DSM 50083T and DSM 50135. J Inorg Biochem, 98 (2), 276-86.
PINHO, M. J., SERRAO, M. P., GOMES, P., HOPFER, U., JOSE, P. A. & SOARES-DA-SILVA, P. (2004). Over-expression of renal LAT1 and LAT2 and enhanced L-DOPA uptake in SHR immortalized renal proximal tubular cells. Kidney Int, 66 (1), 216-26.
QUEIROZ, G., QUINTAS, C., TALAIA, C. & GONCALVES, J. (2004). Coupling to protein kinases A and C of adenosine A2B receptors involved in the facilitation of noradrenaline release in the prostatic portion of rat vas deferens. Neuropharmacology, 47 (2), 216-24.
SILVEIRA, P., VAZ-DA-SILVA, M., MAIA, J., ALMEIDA, L., GAMA, H. & SOARES-DA-SILVA, P. (2004). Effects of enalapril and imidapril in the capsaicin cough challange test and spirometry parameters in healthy volunteers. Therapy, 1 (2), 223-230.
SOARES-DA-SILVA, P. & SERRAO, M. P. (2004). High- and low-affinity transport of L-leucine and L-DOPA by the hetero amino acid exchangers LAT1 and LAT2 in LLC-PK1 renal cells. Am J Physiol Renal Physiol, 287 (2), F252-61.
SOARES-DA-SILVA, P., SERRAO, M. P., PINHO, M. J. & BONIFACIO, M. J. (2004). Cloning and gene silencing of LAT2, the L-3,4-dihydroxyphenylalanine (L-DOPA) transporter, in pig renal LLC-PK1 epithelial cells. Faseb J, 18 (13), 1489-98.
SOUSA, T., MORATO, M., FERNANDES, E., CARVALHO, F. & ALBINO-TEIXEIRA, A. (2004). Xanthine oxidase inhibition by 1,3-dipropyl-8-sulfophenylxanthine (DPSPX), an antagonist of adenosine receptors. J Enzyme Inhib Med Chem, 19 (1), 11-5.
ALMEIDA, L., FALCAO, A., MAIA, J., MAZUR, D., GELLERT, M. & SOARES-DA-SILVA, P. (2005). Single-dose and steady-state pharmacokinetics of eslicarbazepine acetate (BIA 2-093) in healthy elderly and young subjects. J Clin Pharmacol, 45 (9), 1062-6.
ALVELOS, M., FERREIRA, A., BETTENCOURT, P., PIMENTA, J., AZEVEDO, A., SERRAO, P., ROCHA-GONCALVES, F. & SOARES-DA-SILVA, P. (2005). Effect of saline load and metoclopramide on the renal dopaminergic system in patients with heart failure and healthy controls. J Cardiovasc Pharmacol, 45 (3), 197-203.
DIAS, A. G., LOPES, M. A., TRIGO CABRAL, A. T., SANTOS, J. D. & FERNANDES, M. H. (2005). In vitro studies of calcium phosphate glass ceramics with different solubility with the use of human bone marrow cells. J Biomed Mater Res A, 74 (3), 347-55.
FONTES-RIBEIRO, C., NUNES, T., FALCAO, A., NETA, C., LIMA, R., TAVARES, S., ALMEIDA, L., MACEDO, T. & SOARES-DA-SILVA, P. (2005). Eslicarbazepine acetate (BIA 2-093) : relative bioavailability and bioequivalence of 50 mg/mL oral suspension and 200mg and 800mg tablet formulations. Drugs R D, 6 (5), 253-60.
FRAGA, S., PINHO, M. J. & SOARES-DA-SILVA, P. (2005). Expression of LAT1 and LAT2 amino acid transporters in human and rat intestinal epithelial cells. Amino Acids, 29 (3), 229-33.
GOMES, P. & SOARES-DA-SILVA, P. (2005). Up-regulation of apical NHE3 in renal OK cells overexpressing the rodent {alpha}1- subunit of the Na+ pump. Am J Physiol Regul Integr Comp Physiol, 290 R1142-R1150.
GUIMARAES, S. & PINHEIRO, H. (2005). Functional evidence that in the cardiovascular system AT1 angiotensin II receptors are AT1B prejunctionally and AT1A postjunctionally. Cardiovasc Res, 67 (2), 208-15.
LEARMONTH, D. A., BONIFACIO, M. J. & SOARES-DA-SILVA, P. (2005). Synthesis and Biological Evaluation of a Novel Series of "Ortho-Nitrated" Inhibitors of Catechol-O-methyltransferase. J Med Chem, 48 (25), 8070-8.
MAGINA, S., SANTOS, J., COROAS, A., OLIVEIRA, J. G., SERRAO, P., SOARES-DA-SILVA, P., RESENDE, C. & PESTANA, M. (2005). Salt sensitivity of blood pressure in patients with psoriasis on ciclosporin therapy. Br J Dermatol, 152 (4), 773-6.
MAGRO, F., FRAGA, S., RIBEIRO, T. & SOARES-DA-SILVA, P. (2005). Regional intestinal adaptations in Na+,K+-ATPase in experimental colitis and the contrasting effects of interferon-gamma. Acta Physiol Scand, 183 (2), 191-9.
MAGRO, F., FRAGA, S. & SOARES-DA-SILVA, P. (2005). Interferon-gamma-induced STAT1-mediated membrane retention of NHE1 and associated proteins ezrin, radixin and moesin in HT-29 cells. Biochem Pharmacol, 70 (9), 1312-9.
MAGRO, F., FRAGA, S. & SOARES-DA-SILVA, P. (2005). Signaling of short- and long-term regulation of intestinal epithelial type 1 Na+/H+ exchanger by interferon-gamma. Br J Pharmacol, 145 (1), 93-103.
MAGRO, F., PEREIRA, P., CARNEIRO, F., LOPES, J., TEIXEIRA, A., SARMENTO, C., LIMA, J., SARAIVA, A., TEIXEIRA, A. & TAVARELA-VELOSO, F. (2005). Colon stenosis in a patient with ulcerative colitis as a manifestation of mixed mullerian tumor of the peritoneum. Scand J Gastroenterol, 40 (10), 1251-4.
MAGRO, F., PEREIRA, P., CARNEIRO, F. & VELOSO, F. T. (2005). Reactive hepatitis in a patient with Crohn's disease successfully treated with infliximab: does tumor necrosis factor alpha play a role in reactive hepatitis? Inflamm Bowel Dis, 11 (1), 88-90.
MAGRO, F., PEREIRA, P., VELOSO, F. T. & CARNEIRO, F. (2005). Unusual presentation of tuberculosis after infliximab therapy. Inflamm Bowel Dis, 11 (1), 82-4.
MAIA, J., VAZ-DA-SILVA, M., ALMEIDA, L., FALCAO, A., SILVEIRA, P., GUIMARAES, S., GRAZIELA, P. & SOARES-DA-SILVA, P. (2005). Effect of food on the pharmacokinetic profile of eslicarbazepine acetate (BIA 2-093). Drugs R D, 6 (4), 201-6.
MERGULHAO, P., MAGRO, F., PEREIRA, P., CORREIA, R., LOPES, J. M., MAGALHAES, J., DIAS, J. M., CARNEIRO, F. & TAVARELA-VELOSO, F. (2005). Gingival hyperplasia as a first manifestation of Crohn's disease. Dig Dis Sci, 50 (10), 1946-9.
MOURA, E., PINHO COSTA, P. M., MOURA, D., GUIMARAES, S. & VIEIRA-COELHO, M. A. (2005). Decreased tyrosine hydroxylase activity in the adrenals of spontaneously hypertensive rats. Life Sci, 76 (25), 2953-64.
OLIVEIRA, L. & CORREIA-DE-SA, P. (2005). Protein kinase A and Ca(v)1 (L-Type) channels are common targets to facilitatory adenosine A2A and muscarinic M1 receptors on rat motoneurons. Neurosignals, 14 (5), 262-72.
PINHO, D., BESSON, S., SILVA, P. J., DE CASTRO, B. & MOURA, I. (2005). Isolation and spectroscopic characterization of the membrane-bound nitrate reductase from Pseudomonas chlororaphis DSM 50135. Biochim Biophys Acta, 1723 (1-3), 151-62.
REBOLA, N., PORCIUNCULA, L. O., LOPES, L. V., OLIVEIRA, C. R., SOARES-DA-SILVA, P. & CUNHA, R. A. (2005). Long-term effect of convulsive behavior on the density of adenosine A1 and A 2A receptors in the rat cerebral cortex. Epilepsia, 46 Suppl 5 159-65.
RODRIGUES, M. L., BONIFACIO, M. J., SOARES-DA-SILVA, P., CARRONDO, M. A. & ARCHER, M. (2005). Crystallization and preliminary X-ray diffraction studies of a catechol-O-methyltransferase/inhibitor complex. Acta Crystallograph Sect F Struct Biol Cryst Commun, 61 (Pt 1), 118-120.
SAMPAIO-MAIA, B., MOREIRA-RODRIGUES, M., SERRAO, P. & PESTANA, M. (2005). Jejunal dopamine and Na,K+-ATPase activity in nephrotic syndrome. Am J Nephrol, 25 (4), 382-92.
SAMPAIO-MAIA, B., SERRAO, P., GUIMARAES, J. T., VIEIRA-COELHO, M. A. & PESTANA, M. (2005). Renal dopaminergic system activity in the rat remnant kidney. Nephron Exp Nephrol, 99 (2), e46-55.
SHIROSAKI, Y., TSURU, K., HAYAKAWA, S., OSAKA, A., LOPES, M. A., SANTOS, J. D. & FERNANDES, M. H. (2005). In vitro cytocompatibility of MG63 cells on chitosan-organosiloxane hybrid membranes. Biomaterials, 26 (5), 485-93.
SOARES-DA-SILVA, P. & SERRAO, M. P. (2005). Apical and basolateral 4F2hc and the amino acid exchange of L-DOPA in renal LLC-PK(1) cells. Amino Acids, 29 (3), 213-9.
SOARES-DA-SILVA, P., SERRAO, P., FRAGA, S. & PINHO, M. J. (2005). Expression and function of LAT1, a neutral amino acid exchanger, in renal porcine epithelial cell line LLC-PK. Acta Physiol Scand, 185 (1), 71-8.
SOUSA, T., FERNANDES, E., NUNES, C., LARANJINHA, J., CARVALHO, F., PINHO, D., MORATO, M. & ALBINO-TEIXEIRA, A. (2005). Scavenging of nitric oxide by an antagonist of adenosine receptors. J Pharm Pharmacol, 57 (3), 399-404.
VAZ-DA-SILVA, M., LOUREIRO, A. I., NUNES, T., MAIA, J., TAVARES, S., FALCAO, A., SILVEIRA, P., ALMEIDA, L. & SOARES-DA-SILVA, P. (2005). Bioavailability and bioequivalence of two enteric-coated formulations of omeprazole in fasting and fed conditions. Clin Drug Investig, 25 (6), 391-9.
ARAUJO, C. S., ALBUQUERQUE, R. R., JR., RODRIGUES, M. M., MAIA, B. S., MOREIRA, A. F. & PESTANA, M. (2006). Medullar expression of type-A natriuretic peptide receptor in an animal model of hypertension induced by renal mass ablation. Rev Port Cardiol, 25 (4), 419-27.
BEK, M. J., WANG, X., ASICO, L. D., JONES, J. E., ZHENG, S., LI, X., EISNER, G. M., GRANDY, D. K., CAREY, R. M., SOARES-DA-SILVA, P. & JOSE, P. A. (2006). Angiotensin-II type 1 receptor-mediated hypertension in D4 dopamine receptor-deficient mice. Hypertension, 47 (2), 288-95.
BELIAEV, A., LEARMONTH, D. A. & SOARES-DA-SILVA, P. (2006). Synthesis and biological evaluation of novel, peripherally selective chromanyl imidazolethione-based inhibitors of dopamine beta-hydroxylase. J Med Chem, 49 (3), 1191-1197.
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